PubHawk
March 2015 PMID 25639270

Added fructose: a principal driver of type 2 diabetes mellitus and its consequences.

James J DiNicolantonio, James H O'Keefe, Sean C Lucan

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Mentions

155
Peak: 34 in Jul 2019
across 7 sources since Apr 2018

Extended reach

918,728
potential audience

Total likes

213

Video views

4,884

Mentions per month

Apr 2018 – Sep 2025

Where it's discussed

  • Facebook54 posts
  • News45 articles
  • X / Twitter39 posts
  • Blogs12 articles
  • YouTube2 videos
  • Reddit2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The social discussions reveal skepticism about the connection between sugar, especially fructose, and diabetes, exemplified by posts denying causality and referencing past dietary guidelines. The tone is often dismissive or questioning, which demonstrates limited agreement or impactful change, despite some participants expressing moderate interest in reducing sugar intake.

AgreementLow agreement

Most discussions seem skeptical or dismissive, questioning the link between sugar and diabetes rather than fully supporting it.

InterestModerate interest

Posts show moderate interest, with some calling for reduction or questioning sugar's role but few engaging deeply with the scientific content.

EngagementModerate engagement

Many participants express opinions with limited detailed analysis, indicating a surface level of engagement rather than extensive discussion.

ImpactLow impact

The discussions reflect some disagreement and skepticism, suggesting the article has limited influence on changing opinions or behaviors.

Abstract in brief

  • Added sugars like sucrose and high-fructose corn syrup are linked to the development of type 2 diabetes and increase cardiovascular risk, especially when they contain high levels of fructose.
  • Whole foods such as fruits and vegetables containing fructose are not harmful and may even help prevent diabetes and heart problems, unlike added sugars.
  • Reducing added sugar intake to around 5% of total calories, as recommended by the World Health Organization, can improve glucose tolerance and lower the risk of diabetes and related health issues.
Read the full abstract

Top posts

Most liked on X and Bluesky
James DiNicolantonio
@drjamesdinic · X

The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical trial in 1981 showing that higher sugar intakes more than doubled the rates of prediabetes/diabetes https://t.co/xLqXr74093 https://t.co/G6o7j19sNT

Jul 1, 2019 · 137 likes · 41 shares · 208,289 followers View post →
James DiNicolantonio
@drjamesdinic · X

@El_Duderino_788 Unfortunately even when controlling for calories sugar is worse https://t.co/xpiDsMu2we

Apr 25, 2022 · 2 likes · 208,289 followers View post →
Alperen
@Naverma21 · X

@PrecieuxO @JarretNoDegree @spectatorindex https://t.co/o4xtChEifG Aside from this study, dispropriate ratio of fructose to glucose are why Americans are more prone to fructose malabsorption. HFCS, while making things sweeter with less calories, will prevent you from digesting fructose. Sugar is sugar is not sugar. https://t.co/kwEHyK3FCL

Jun 29, 2023 · 2 likes · 36 followers View post →
Danni Friedland
@DanniFriedland · X

@Nst24Shem @ZuckermanRoy @ariyederi @bezalelsm יש דווקא כמה הוכחות מדעיות. היה בהתחלה בלבול בין כל סוכר - שבאמת לא הוכח. יש קונסנזוס שסוכר במשקאות ספציפית הוא בקשר ישיר לסכרת סוג 2. https://t.co/ciLS2h2EyM https://t.co/M3uKrvFTzc כמובן שיש קושי מהותי לחקור תזונה בקנה מידה כזה. אבל להגיד שמעולם לא הוכח זה ממש לא נכון

Dec 18, 2023 · 1 like · 717 followers View post →
James DiNicolantonio
@drjamesdinic · X

@BhusriHeart https://t.co/XVaLTdOx8j and https://t.co/xpiDsMu2we

Jul 2, 2021 · 208,289 followers View post →
Tim Noakes
@ProfTimNoakes · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 158,227 followers View post →

All mentions

Dirty Devotee
@dirtydevotee.bsky.social · Bluesky

No, type-2 #diabetes is not caused by a parasite. Please stop letting scammers kill you. #SpotTheScam pubmed.ncbi.nlm.nih.gov/25639270/

Sep 19, 2025 View post →
Danni Friedland
@DanniFriedland · X

@Nst24Shem @ZuckermanRoy @ariyederi @bezalelsm יש דווקא כמה הוכחות מדעיות. היה בהתחלה בלבול בין כל סוכר - שבאמת לא הוכח. יש קונסנזוס שסוכר במשקאות ספציפית הוא בקשר ישיר לסכרת סוג 2. https://t.co/ciLS2h2EyM https://t.co/M3uKrvFTzc כמובן שיש קושי מהותי לחקור תזונה בקנה מידה כזה. אבל להגיד שמעולם לא הוכח זה ממש לא נכון

Dec 18, 2023 · 1 like · 717 followers View post →
Alperen
@Naverma21 · X

@PrecieuxO @JarretNoDegree @spectatorindex https://t.co/o4xtChEifG Aside from this study, dispropriate ratio of fructose to glucose are why Americans are more prone to fructose malabsorption. HFCS, while making things sweeter with less calories, will prevent you from digesting fructose. Sugar is sugar is not sugar. https://t.co/kwEHyK3FCL

Jun 29, 2023 · 2 likes · 36 followers View post →
James DiNicolantonio
@drjamesdinic · X

@El_Duderino_788 Unfortunately even when controlling for calories sugar is worse https://t.co/xpiDsMu2we

Apr 25, 2022 · 2 likes · 208,289 followers View post →
Luca Nicora
@Lucanicora · X

5. Reduce sugar I want candyyyy Sugar (https://t.co/KeYEvO5prO) contains fructose, which is linked to many chronic diseases (https://t.co/CCykgUhhJJ) when consumed excessively. So not only bad for your belly (https://t.co/C31l9A3tyc)....

Jan 11, 2022 · 502 followers View post →
James DiNicolantonio
@drjamesdinic · X

@BhusriHeart https://t.co/XVaLTdOx8j and https://t.co/xpiDsMu2we

Jul 2, 2021 · 208,289 followers View post →
Lesley Johnson
@LesleyLelly88 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 10, 2019 · 41 shares · 738 followers View post →
Marika Sboros - Journalist, editor, author.
@MarikaSboros · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 10, 2019 · 41 shares · 15,963 followers View post →
Graham Sinclair
@esgarchitect · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 6, 2019 · 41 shares · 6,600 followers View post →
Vet Goed
@VetGoed · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 3, 2019 · 41 shares · 386 followers View post →
Ian Partridge
@ianpartridgecom · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 3, 2019 · 41 shares · 1,156 followers View post →
Brooke Miller M D
@Brookemillermd · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 3,791 followers View post →
Leo Monterosso
@LittleOlMe97 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 2,470 followers View post →
BroughtyBoy
@brotyboy · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 2,036 followers View post →
Nutricionista Jônatas Galasso
@Jojolowcarb · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 618 followers View post →
Frank Stewart
@fstew7 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 65 followers View post →
Dr Lisa McGrath
@conorandlisa · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 681 followers View post →
Ahmad Zahar
@Kuahmd · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 782 followers View post →
Martin Sip
@martinsipx · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 2, 2019 · 41 shares · 1,097 followers View post →
KT Carnivore
@kt_szymanski · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 68 followers View post →
Jason Loera
@fastreps · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 1,177 followers View post →
A
@a_muniz5 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 32 followers View post →
Al Soto
@AlSoto9 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 693 followers View post →
Kanjoos
@astingymiser · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 15 followers View post →
Jorge Riquelme
@RiquelmeJorge · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 841 followers View post →
The Taoss
@thetaoss · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 81 followers View post →
DiegoNS
@DiegoNSalman · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 7,965 followers View post →
Guillermo Rodríguez Navarrete
@Nutrillermo · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 41,839 followers View post →
Ana Cláudia
@Anawsantos · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 363 followers View post →
Neowolf
@Neowolf2 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 102 followers View post →
Tim Noakes
@ProfTimNoakes · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 158,227 followers View post →
Penelophe
@PCK0512 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 115 followers View post →
Rafael Galarraga
@hormesistrain · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 167 followers View post →
DiscoStew
@DiscoStew66 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 10,789 followers View post →
Agnes Ayton
@AgnesAyton · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 7,428 followers View post →
Mad
@MadPharmacist1 · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 6,496 followers View post →
Eric Rodgers
@DrEricRodgers · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 3,725 followers View post →
Larry Diamond
@natureboyrr · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 5,626 followers View post →
Rick
@RickCartwright · X

RT @drjamesdinic: The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical tria…

Jul 1, 2019 · 41 shares · 2,803 followers View post →
James DiNicolantonio
@drjamesdinic · X

The US 1985 Dietary Guidelines specifically said consuming too much sugar does NOT cause diabetes despite a clinical trial in 1981 showing that higher sugar intakes more than doubled the rates of prediabetes/diabetes https://t.co/xLqXr74093 https://t.co/G6o7j19sNT

Jul 1, 2019 · 137 likes · 41 shares · 208,289 followers View post →