PubHawk
Exp Clin Psychopharmacol February 2015 PMID 25643025

A brief history of the development of antidepressant drugs: from monoamines to glutamate.

Todd M Hillhouse, Joseph H Porter

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Mentions

67
Peak: 7 in Oct 2025
across 6 sources since Apr 2021

Extended reach

187,481
potential audience

Total likes

17,598

Video views

186,852

Mentions per month

Apr 2021 – Dec 2025

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AI synopsis

What people are saying

The posts primarily reference the technical aspects of database security and vulnerabilities, with words like 'vulnerabilities', 'breach', and 'scanner' indicating a focus on cybersecurity rather than mental health research, which results in low agreement, interest, and engagement related to the article's content on antidepressants.

AgreementStrong disagreement

The discussion only briefly mentions the development of the tool in relation to database security, showing little interest in the article about antidepressant history.

InterestLow interest

The focus on technical details of database vulnerabilities does not reflect interest in neuropharmacology or antidepressant research.

EngagementLow engagement

The comments are superficial, emphasizing general security topics rather than engaging deeply with the scientific content of the publication.

ImpactNeutral impact

The post's impact on the broader understanding of antidepressant development is minimal as it pertains mainly to cybersecurity, not psychiatric pharmacology.

Abstract in brief

  • The development of antidepressant drugs has largely focused on monoamines, but their effectiveness is limited, prompting research into other systems like glutamate.
  • Since the discovery of the first antidepressant treatment over 50 years ago, drugs targeting the glutamatergic system, especially the NMDA receptor, like ketamine, have shown rapid and sustained antidepressant effects.
  • These promising findings suggest that exploring glutamatergic mechanisms could lead to new, more effective treatments for major depressive disorder, beyond traditional monoamine-based medications.]
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Pete Finnigan
@petefinnigan.bsky.social · Bluesky

PFCLScan can be used to look for vulnerabilities in an Oracle database. I have written a brief history of the development of this tool as someone asked me about it recently - www.petefinnigan.com/weblog/archi... - #oracle #security #pfclscan #vulnerability #scanner #breach #databreach #datasecurity

May 15, 2025 · 2 likes View post →
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Real Python
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Jun 30, 2025 · 1 like View post →
Pete Finnigan
@petefinnigan.bsky.social · Bluesky

PFCLScan can be used to look for vulnerabilities in an Oracle database. I have written a brief history of the development of this tool as someone asked me about it recently - www.petefinnigan.com/weblog/archi... - #oracle #security #pfclscan #vulnerability #scanner #breach #databreach #datasecurity

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