Cardiovasc Diabetol February 2015 PMID 25645749

Treatment-dependent and treatment-independent risk factors associated with the risk of diabetes-related events: a retrospective analysis based on 229,042 patients with type 2 diabetes mellitus.

Thomas Wilke, Sabrina Mueller, Antje Groth, Andreas Fuchs, Lisa Seitz, Joachim Kienhöfer, Ulf Maywald, Rainer Lundershausen, Martin Wehling

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Mentions

16
Peak: 10 in Jun 2023
across 2 sources since Jun 2023

Extended reach

881,221
potential audience

Total likes

20,246

Video views

712,757

Mentions per month

Jun 2023 – May 2025

Where it's discussed

  • X / Twitter14 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate high interest by analyzing data nuances, such as pointing out that unadjusted data can mislead conclusions about diabetes risk factors. Words like 'illusion,' 'stupid,' and critiques of simplistic health advice highlight a tone of analytical skepticism and urgency, emphasizing the importance of rigorous data interpretation and its significance for health decisions.

AgreementModerate agreement

Most contributions support the article's findings, emphasizing the importance of data adjustment and challenging common assumptions about cholesterol and blood pressure levels.

InterestHigh interest

Discussions are highly engaging, with posters actively analyzing and critiquing the research methodology and implications.

EngagementHigh engagement

Participants delve into detailed critiques, referencing specific data points like optimal blood sugar levels and mortality, demonstrating deep engagement.

ImpactHigh impact

The conversations have potential to influence perceptions about health management and highlight misconceptions spread through social discussions.

Abstract in brief

  • This study analyzed a large group of over 229,000 patients with type 2 diabetes to identify factors that predict the risk of serious health events like hospitalizations and death, focusing on both treatment-related and non-treatment-related risks.
  • Key factors increasing the risk included older age, male gender, higher comorbidity scores, previous health events, and the number of medications, while optimal blood pressure and blood sugar levels (HbA1C around 6.5% and systolic BP 130-140 mmHg) were associated with the lowest risk, highlighting the importance of proper management.
  • The findings emphasize that both over- and undertreatment can be harmful, especially in older, sicker patients, suggesting that personalized treatment targets for blood pressure and HbA1C are crucial to reducing the risk of severe diabetes-related complications.

Top posts

Most liked on X and Bluesky
Gil Carvalho MD PhD
@NutritionMadeS3 · X

Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortality next time a TikTok guru advises high cholesterol bc of mortality associations, ask if prediabetes and hypertension are also ideal https://t.co/9Wecbho7md https://t.co/42PC9P5vYK

Jun 11, 2023 · 58 likes · 8 shares · 28,172 followers View post →
riggers
@deportriggers · X

@RHd1983 @EstebanDL @lipo_fan @LDLSkeptic @Marion436842126 @realDaveFeldman 2/ and here is the paper that graph is drawn from https://t.co/ra802M5o5N Notice their low quality data methodology is exactly what you think evidence should be. This is why you can't develop a correct worldview.

Mar 9, 2025 · 1 like · 112 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 99,334 followers View post →
Summer M
@SummerMinvest · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 12,339 followers View post →
Michael Joseph
@Nutradvance · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 11,778 followers View post →
htw
@heniek_htw · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 11,358 followers View post →

All mentions

anonemus349832
@anonemus349832 · X

@mellexnano @LigmaTSPro @nicknorwitz I've done none of the above. All I did was point out that fair comparisons have to be made otherwise it would appear diabetes is healthy, as the unadjusted data clearly shows. https://t.co/KrGee7FHWR

May 17, 2025 · 74 followers View post →
riggers
@deportriggers · X

@RHd1983 @EstebanDL @lipo_fan @LDLSkeptic @Marion436842126 @realDaveFeldman 2/ and here is the paper that graph is drawn from https://t.co/ra802M5o5N Notice their low quality data methodology is exactly what you think evidence should be. This is why you can't develop a correct worldview.

Mar 9, 2025 · 1 like · 112 followers View post →
riggers
@deportriggers · X

@PomHauz @DrGaryMcGowan No it's raw unadjusted data for mortality/a1c. You'll notice its the same graph as cholesterol and blood pressure. When people say high cholesterol lives longer, they actually mean diabetics live longer, they don't know it is a statistical illusion. https://t.co/ra802M5o5N

Dec 9, 2024 · 112 followers View post →
riggers
@deportriggers · X

@BrettJohn17 @CaryKelly11 @DrEenfeldt Notice optimal blood sugar had the highest all cause mortality, and diabetics had the lowest. https://t.co/ra802M5o5N

Nov 29, 2024 · 112 followers View post →
riggers
@deportriggers · X

@ThelastStyleb16 @1975Hotsauce @drscottyk 2/ Lowest risk of death in elderly are diabetics https://t.co/ra802M5o5N So whoever told you that high cholesterol was good for old people, this is the level of stupid you're looking at. They don't have any idea what they are talking about. https://t.co/90iqRLTpIO

Nov 19, 2024 · 112 followers View post →
Biomass Bob
@SentientBlobBob · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 836 followers View post →
muffmuff
@muffmuff5 · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 3,190 followers View post →
Michael Joseph
@Nutradvance · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 11,778 followers View post →
htw
@heniek_htw · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 11,358 followers View post →
Summer M
@SummerMinvest · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 12,339 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 99,334 followers View post →
leroyvanderberg
@physiquecheck · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 10 followers View post →
Simon Brežan MD
@BrezanSimonMD · X

RT @NutritionMadeS3: Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortalit…

Jun 11, 2023 · 8 shares · 782 followers View post →
Gil Carvalho MD PhD
@NutritionMadeS3 · X

Another study shows U-curve for blood pressure and HbA1c 140-150mmHg and 6-6.5% HbA1c associated with lowest mortality next time a TikTok guru advises high cholesterol bc of mortality associations, ask if prediabetes and hypertension are also ideal https://t.co/9Wecbho7md https://t.co/42PC9P5vYK

Jun 11, 2023 · 58 likes · 8 shares · 28,172 followers View post →