This collection of discussions demonstrates a strong collective interest and agreement regarding the importance of the systematic review on SSRI withdrawal, with posters referencing specific sections like long-lasting symptoms, delayed effects, and the need for better terminology. The tone ranges from professional critique to advocacy for increased awareness, emphasizing the potential impact of recognizing withdrawal symptoms on clinical practices and patient safety.
AgreementStrong agreement
Most discussions acknowledge the significance of the systematic review by Fava et al., emphasizing the need to recognize withdrawal symptoms and criticize underreporting or trivialization in clinical practice.
InterestHigh interest
Participants show high interest by referencing specific research findings and emphasizing the long-term effects and recognition of withdrawal symptoms that have often been overlooked.
EngagementModerate engagement
Posts reflect active engagement through citations of the paper, debates over clinical responses, and mentions of various health organizations, indicating meaningful discussion rather than superficial mentioning.
ImpactHigh impact
The discussions suggest this publication could influence clinical practice and public awareness about long-term effects of SSRIs, as many argue it highlights critical issues in medication management and patient well-being.
Abstract in brief
The systematic review highlights that SSRIs, commonly used antidepressants, can cause withdrawal symptoms when discontinued, with symptoms often appearing within days and lasting several weeks, sometimes with delayed onset or persistence.
The prevalence of withdrawal symptoms varies across studies and is frequently underreported due to challenges in identifying these symptoms, which can be mistaken for relapse of the original condition.
The authors suggest that the terminology should shift from "discontinuation syndrome" to "withdrawal syndrome" to better emphasize the potential vulnerabilities caused by SSRIs and advise clinicians to be aware of this risk when stopping these medications.]
The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was first released to the public in 1987.
https://t.co/0iNjqYKCo9
Mar 3, 2023 · 59 likes · 16 shares · 1,143 followersView post →
@Louthewarrior @DrHannahBelcher @functionalnurse Fava et al published this paper in 2015 concerning antidepressant withdrawal.
"Many variations are possible, including late onset and/or longer persistence of disturbances."
https://t.co/WkWLpRfuvY
Oct 11, 2025 · 4 likes · 2 shares · 1,924 followersView post →
This video shares personal experiences with the American mental healthcare system and the lasting damage caused by systemic failures. It emphasizes the need for reform and highlights the importance of informed consent…
Stopping Zoloft suddenly can cause withdrawal symptoms like brain zaps, dizziness, and mood swings. This video explains how Zoloft works, what happens during abrupt discontinuation, and the importance of proper tapering…
RT @DuthieAlyne: @Louthewarrior @DrHannahBelcher @functionalnurse Fava et al published this paper in 2015 concerning antidepressant withdra…
Oct 11, 2025 · 2 shares · 1,854 followersView post →
AD
Alyne Duthie
@DuthieAlyne · X
@Louthewarrior @DrHannahBelcher @functionalnurse Fava et al published this paper in 2015 concerning antidepressant withdrawal.
"Many variations are possible, including late onset and/or longer persistence of disturbances."
https://t.co/WkWLpRfuvY
Oct 11, 2025 · 4 likes · 2 shares · 1,924 followersView post →
@depressionsliga Dazu kommen Entzugssymptome, die nicht dadurch besser werden, dass sie verharmlosend „Absetzsyndrom“ genannt werden. Sie bestehen bei über der Hälfte der Behandelten länger als zwei Wochen, darunter Stimmungsschwankungen, Ängste und vieles mehr. 12/n
https://t.co/3memgfPNBU
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 6, 2023 · 16 shares · 294 followersView post →
AB
Andy O Barnes
@AndreaB63735256 · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 5, 2023 · 16 shares · 1,244 followersView post →
PW
PSSD WARRIOR
@PssdWarrior · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 1,434 followersView post →
S
sic
@kimvie · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 2,526 followersView post →
WF
WJW Mental Health Legal Fund
@wjwmhlf · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 1,303 followersView post →
JD
Jackie Welton DiPillo
@JaxDiP · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 670 followersView post →
LV
La Double Vie
@Onbodyandsoul · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 1,094 followersView post →
D
Davison
@DavisonVideo · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 6,864 followersView post →
IM
Informed Consent Matters
@stopharmingus · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 1,819 followersView post →
KC
Kim Climer
@RhetoricalGirl0 · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 3,422 followersView post →
RR
recovery&renewal
@recover2renew · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 4, 2023 · 16 shares · 4,162 followersView post →
JJ
Julias Jones
@JsJones994 · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 3, 2023 · 16 shares · 159 followersView post →
EL
Eddy Lang
@EddyLang1 · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 3, 2023 · 16 shares · 3,849 followersView post →
C
cheesyredrocket
@cheesyredrocket · X
RT @BrookeSiem: The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was fi…
Mar 3, 2023 · 16 shares · 3,094 followersView post →
BS
Brooke Siem — Subscribe to my Substack
@BrookeSiem · X
The first systematic review of antidepressant withdrawal did not even exist until 2015, a full 28 years after Prozac was first released to the public in 1987.
https://t.co/0iNjqYKCo9
Mar 3, 2023 · 59 likes · 16 shares · 1,143 followersView post →
CL
capsula lunar
@capsulalunar · X
Ustedes acudirían a una psiquiatra que ningunea a la más minima crítica?
Es hasta un riesgo
Si los medicamentos no tuvieran efectos a largo plazo (que los tienen), para qué los recetan?
https://t.co/iJD2qvZW9O
https://t.co/7gO9wZrubG https://t.co/qvJBerulAT https://t.co/KPace3VrXg
RT @DuthieAlyne: @recover2renew You would need to check that your patient wasn't going through withdrawal. Fava et al, 'Withdrawal Symptoms…
Feb 15, 2022 · 1 share · 4,162 followersView post →
AD
Alyne Duthie
@DuthieAlyne · X
@recover2renew You would need to check that your patient wasn't going through withdrawal. Fava et al, 'Withdrawal Symptoms after Selective Serotonin Reuptake Inhibitor Discontinuation: A Systematic Review', Psychother Psychsom 2015; 84:72-98. Under Signs and Symptoms: General > tachycardia.
Feb 7, 2022 · 1 like · 1 share · 1,924 followersView post →
RR
recovery&renewal
@recover2renew · X
RT @recover2renew: per thread.
This is happening - to too many people
Refs for infographic:
1) AD Withdrawal - Fava et al 2015 https://t.c…
Oct 1, 2021 · 1 share · 4,162 followersView post →
RR
recovery&renewal
@recover2renew · X
per thread.
This is happening - to too many people
Refs for infographic:
1) AD Withdrawal - Fava et al 2015 https://t.co/Rk87hmxsIg
2) #MUS JCMPH Guidance RCPsych
https://t.co/nVbQR5pOdb https://t.co/J7J4P4oXfs
Oct 1, 2021 · 1 share · 4,162 followersView post →
Feb 16, 2021 · 1 like · 3,754 followersView post →
RR
recovery&renewal
@recover2renew · X
RT @recover2renew: Rediscovering this paper … so much important stuff in here: Withdrawal Symptoms after Selective Serotonin Reuptake Inhib…
May 18, 2020 · 1 share · 4,162 followersView post →
RR
recovery&renewal
@recover2renew · X
Rediscovering this paper … so much important stuff in here: Withdrawal Symptoms after Selective Serotonin Reuptake Inhibitor Discontinuation: A Systematic Review https://t.co/OuF8q38CBG
May 18, 2020 · 1 like · 1 share · 4,162 followersView post →
KD
Kindly #deprescribe -- taper psychiatric drugs
@Altostrata · X
@ferguskane Your source being Fava, G.A., Gatti, A., Belaise, C., Guidi, J., Offidani, E., 2015. Withdrawal Symptoms after Selective Serotonin Reuptake Inhibitor Discontinuation: A Systematic Review. PPS 84, 72–81. https://t.co/ZAWn4DViSO -- correct? https://t.co/2zafyRQ8iw https://t.co/DuG2Td1I1P
Escitalopram- Drug Information | PDF | Selective Serotonin ...
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Psychother Psychosom. 2015;84(2):72-81. doi:10.1159/000370338 [PubMed 25721705] 93. Fava M. Prospective studies of adverse events related to antidepressant ...
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Psychotherapy and Psychosomatics, 84, 72–81. http://dx.doi.org/10.1159/000370338 Gavin, N. I., Gaynes, B. N., Lohr, K. N., Meltzer- Brody, S., Gartlehner, G ...
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... doi:10.1159/000370338. Last updated 12 February 2021 16:58. Citation: The Pharmaceutical Journal, New classification system to diagnose SSRI withdrawal ...
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https://doi.org/10.1159/000370338. withdrawal support services: recommendations from 708 patients. Psychiatry Res. Gastaldon, C., Schoretsanitis, G ...
Antidepressant Switching and Withdrawal Guide | PDF ...
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http://dx.doi.org/10.1159/000370338. Full text free online at nps.org.au/australianprescriber 79. VOLUME 39 : NUMBER 3 : JUNE 2016. ARTICLE Switching and ...