Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort.
Various posts highlight the significant findings from the study, such as the 46% increased risk of diabetes and the dose-dependent effects, showing a high level of interest and deep engagement. Words like 'support,' 'mechanisms,' and references to detailed data and clinical implications reflect a serious tone, underscoring the perceived impact on medical understanding and practice.
AgreementStrong agreement
Most discussions acknowledge and support the study’s findings, emphasizing the link between statin use and increased diabetes risk.
InterestHigh interest
The discussions demonstrate high interest, with many referencing detailed research data, mechanisms, and implications.
EngagementHigh engagement
Users are deeply engaging by citing specific studies, discussing dose dependency, and debating clinical implications.
ImpactHigh impact
The collective tone indicates that these discussions see the findings as highly impactful, influencing views on statin safety and cardiovascular health.
Abstract in brief
This study followed nearly 9,000 men over 6 years and found that those taking statins had a 46% higher risk of developing type 2 diabetes, primarily due to reduced insulin sensitivity and secretion.
The risk increase was linked to higher doses of simvastatin and atorvastatin, and statin users showed worse blood sugar control during tests, including higher 2-hour glucose levels.
The findings suggest that statins may contribute to diabetes risk by impairing how the body responds to insulin and how much insulin is secreted, with the effect being dose-dependent.]
@drjkahn @PeterAttiaMD @ethanjweiss @ProfTimNoakes @KenDBerryMD @lowcarbGP @ifixhearts @DrPascalMeier sure Joel, the 1% reduction in coronary events with statins is so impressive that it offsets the doubling in the rate of new onset statins over 6 years, as well as numerous other adverse effects
(graph shows newTD2 in statin users vs non-users)
DOI 10.1007/s00125-015-3528-5 https://t.co/YGJxx3k4nX
May 5, 2023 · 51 likes · 4 shares · 45,089 followersView post →
GP
Gil Carvalho MD PhD
@NutritionMadeS3 · X
Statins and new onset diabetes
A step-by-step guide to minimizing risk
https://t.co/zXzmUjvjL9
For the “statin curious” who wonder about diabetes, and risk/benefit profile.
Courtesy @NutritionMadeS3
https://t.co/aslYNKitTf
Don’t miss the commentary around sound byte based decision-making at 24:55
@EricTopol @aydinnalper @TheLancetEndo Why was Cederberg et al not included in this MA?
doi:10.1007/s00125-015-3528-5
"Results Participants on statin treatment (N=2,142) had a 46% increased risk of type 2 diabetes (adjusted HR 1.46 [95% CI 1.22, 1.74]). The risk was dose dependent for simvastatin and atorvastatin.
Mar 28, 2024 · 7 likes · 1 share · 45,089 followersView post →
@EricTopol 46% increase in risk of T2D with statins in the most comprehensive dose-response assessment of statins and new onset T2D
doi:10.1007/s00125-015-3528-5 https://t.co/kAivIYBAHU
Mar 28, 2024 · 6 likes · 3 shares · 45,089 followersView post →
Do statins cause diabetes? This video explores how factors like dosage and type influence diabetes risk in statin users, emphasizing the potential benefits for cardiovascular health versus the risk of new-onset…
Many pilots have a growing concern as they approach retirement age about cholesterol management and the effectiveness of statin drugs in reducing cardiovascular risk. This video delves into whether cholesterol is truly…
@SandmanRT The science is very clear on how statin induce diabetes. However, the FDA, the pharma industry, and some prescribing doctors
Feb 13, 2025 · 1 like · 19,407 followersView post →
GH
Gary Harris
@iloveidpol · X
RT @Marion436842126: Statin treatment increases the risk of Type 2 Diabetes by 46%, attributable to decreases in insulin sensitivity and in…
Dec 6, 2024 · 147 shares · 529 followersView post →
O
#onewiththemachine
@CrazyKatSeez · X
RT @Marion436842126: Statin treatment increases the risk of Type 2 Diabetes by 46%, attributable to decreases in insulin sensitivity and in…
Nov 29, 2024 · 147 shares · 83 followersView post →
BB
Boca Boca
@CommunistoObama · X
Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort - PubMed https://t.co/TSUMXOPozu
RT @Marion436842126: Statin treatment increases the risk of Type 2 Diabetes by 46%, attributable to decreases in insulin sensitivity and in…
Nov 29, 2024 · 147 shares · 2,062 followersView post →
T
TD57903
@TD57903 · X
RT @Marion436842126: Statin treatment increases the risk of Type 2 Diabetes by 46%, attributable to decreases in insulin sensitivity and in…
Nov 29, 2024 · 147 shares · 1,285 followersView post →
P
PlanetOptimism
@planetoptimism · X
@DrGaryMcGowan @BenBikmanPhD You are lying. I know it, you know it, everyone knows it. Here are some facts:
https://t.co/THgywPjHJj
https://t.co/qGtJM92PL2
https://t.co/1C47W2DZ5q
@cooperjohnye @JesperLundbom @Drlipid There is no evidence for what you wrote, it is only an assumption. And here is another problem with statins:
https://t.co/1C47W2DZ5q I always wonder why people always offer poison to others, although they have never used it themselves and are not going to?
Aug 31, 2024 · 4 likes · 1 share · 524 followersView post →
YM
Yas MD
@derossi66 · X
RT @Marion436842126: Statin treatment increases the risk of Type 2 Diabetes by 46%, attributable to decreases in insulin sensitivity and in…
Aug 30, 2024 · 147 shares · 990 followersView post →
YM
Yas MD
@derossi66 · X
Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort - PubMed https://t.co/jSKBZpCNJb
@bigfatsurprise @RobertKennedyJr No doubt food is important but there are other influences on insulin sensitivity. Take Satins for example......https://t.co/2QZogux6UT
RT @LDLSkeptic: @EricTopol @aydinnalper @TheLancetEndo Why was Cederberg et al not included in this MA?
doi:10.1007/s00125-015-3528-5
"Resu…
Mar 29, 2024 · 1 share · 1,963 followersView post →
MI
m(^_^;)imran
@imranjamadar · X
RT @LDLSkeptic: @EricTopol 46% increase in risk of T2D with statins in the most comprehensive dose-response assessment of statins and new o…
Mar 28, 2024 · 3 shares · 345 followersView post →
SI
Shashi Iyengar | Metabolic Health India®
@shashiiyengar · X
RT @LDLSkeptic: @EricTopol 46% increase in risk of T2D with statins in the most comprehensive dose-response assessment of statins and new o…
Mar 28, 2024 · 3 shares · 29,080 followersView post →
DD
David Diamond
@LDLSkeptic · X
@EricTopol 46% increase in risk of T2D with statins in the most comprehensive dose-response assessment of statins and new onset T2D
doi:10.1007/s00125-015-3528-5 https://t.co/kAivIYBAHU
Mar 28, 2024 · 6 likes · 3 shares · 45,089 followersView post →
DD
David Diamond
@LDLSkeptic · X
@EricTopol @aydinnalper @TheLancetEndo Why was Cederberg et al not included in this MA?
doi:10.1007/s00125-015-3528-5
"Results Participants on statin treatment (N=2,142) had a 46% increased risk of type 2 diabetes (adjusted HR 1.46 [95% CI 1.22, 1.74]). The risk was dose dependent for simvastatin and atorvastatin.
Mar 28, 2024 · 7 likes · 1 share · 45,089 followersView post →
M
Methi
@MasalaFry69 · X
RT @hawkins_carole: @ClairSaysThis @MasalaFry69 Risk of diabetes with statins
The BMJ
https://t.co/eXVOX4XMha › content › bmj-2022-071727
b…
Feb 23, 2024 · 1 share · 6,724 followersView post →
CH
Carole Hawkins
@hawkins_carole · X
@ClairSaysThis @MasalaFry69 Risk of diabetes with statins
The BMJ
https://t.co/eXVOX4XMha › content › bmj-2022-071727
by IA Mansi · 2023 · Cited by 9 — Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study ...
Feb 23, 2024 · 1 like · 1 share · 7,999 followersView post →
FE
For health-promoting environments
@SilkeLeFay · X
#prevention #NCDs #diabetes #cholesterol 60-day dispensing #publichealth
Participants on statin treatment
had a 46% increased risk of
type 2 diabetes.
.
https://t.co/2wwFjLXHDz
@TheAtlantic @sarahzhang #aging #geriatrics #diabetes #cataract #health
Statins
are associated with
an increased risk of
cataracts.
https://t.co/wlACRGpmc5
.
Participants on statin treatment
had a 46% increased risk of
type 2 diabetes.
Impaired insulin sensitivity and secretion
https://t.co/2wwFjLXHDz
#agedcare #statins #publichealth #diabetes #NCDs #CDoH #primaryhealthcare #nurses #nursing #aging #health #CKD
Participants on statin treatment
had a 46% increased risk of
type 2 diabetes.
The risk was dose dependent for
simvastatin and atorvastatin.
.
https://t.co/2wwFjLXHDz
O aumento do risco de #diabetes com o tratamento com #estatina está associado à diminuição da sensibilidade à insulina e secreção de insulina: um estudo de acompanhamento de 6 anos da coorte METSIM. https://t.co/U9YV7Cgq3E
May 5, 2023 · 4 shares · 29,080 followersView post →
DD
David Diamond
@LDLSkeptic · X
@drjkahn @PeterAttiaMD @ethanjweiss @ProfTimNoakes @KenDBerryMD @lowcarbGP @ifixhearts @DrPascalMeier sure Joel, the 1% reduction in coronary events with statins is so impressive that it offsets the doubling in the rate of new onset statins over 6 years, as well as numerous other adverse effects
(graph shows newTD2 in statin users vs non-users)
DOI 10.1007/s00125-015-3528-5 https://t.co/YGJxx3k4nX
May 5, 2023 · 51 likes · 4 shares · 45,089 followersView post →
GP
Gil Carvalho MD PhD
@NutritionMadeS3 · X
@nutrologia_e some statins classes accelerate progression to t2d by 4-6wks in people at risk at baseline. circumvented by dose and lifestyle measures
importantly, risk of CVD and death still reduced by statins even in people at highest risk of t2d
for more detail:
https://t.co/zXzmUjvjL9
For the “statin curious” who wonder about diabetes, and risk/benefit profile.
Courtesy @NutritionMadeS3
https://t.co/aslYNKitTf
Don’t miss the commentary around sound byte based decision-making at 24:55
Jan 11, 2019 · 2 shares · 6,157 followersView post →
DD
David Diamond
@LDLSkeptic · X
@DrScottMurray @bschermd @erreyedoc @andrewcuckill @DrAseemMalhotra @KenDBerryMD @ProfKausikRay @BcsPresident see Cederberg
⬆️risk of T2D w statins w mechanisms
figure=time/dose-dep ⬆️in T2D
DOI 10.1007/s00125-015-3528-5
"Increased risk of diabetes with statin treatment is associated
with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort" https://t.co/Y9OnYme7HM
Jan 11, 2019 · 2 likes · 2 shares · 45,089 followersView post →
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