June 2015 PMID 25844730

Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship.

Hannah Arem, Steven C Moore, Alpa Patel, Patricia Hartge, Amy Berrington de Gonzalez, Kala Visvanathan, Peter T Campbell, Michal Freedman, Elisabete Weiderpass, Hans Olov Adami, Martha S Linet, I-Min Lee, Charles E Matthews

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Mentions

84
Peak: 9 in May 2022
across 7 sources since Feb 2016

Extended reach

458,283
potential audience

Total likes

1,410

Video views

48,470

Mentions per month

Feb 2016 – Oct 2026

Where it's discussed

  • X / Twitter33 posts
  • Facebook26 posts
  • Instagram11 posts
  • News6 articles
  • YouTube5 videos
  • TikTok2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The collection mainly reflects a mix of endorsement of the health benefits of physical activity, caveats about overinterpretation (especially around “how much is too much”), and concern about misinformation in public discourse. Tone ranges from cautious optimism to ethical critique, with mentions of seminars and calls for evidence-based interpretation. Word choices like “etik,” “dezenformasyona,” and “sağlık” signal concerns about ethics and public health impact, while phrases like “risk reduced by up to 30%” or “3-5x recommendation” show uptake of the study’s quantified messages. Overall, discussions emphasize appreciating the study’s findings while warning against sensationalism and misrepresentation in social discussions about exercise and mortality.

AgreementNeither agree nor disagree

Overall ambivalent to mixed: some posts echo the study's benefits, others challenge or question due to ethics or misinformation concerns, leading to neutral stance overall.

InterestModerate interest

Moderate to high interest: many posts show curiosity or concern about dose-response and potential over- or under-interpretation of results.

EngagementModerate engagement

Engagement is thoughtful and sometimes confrontational; there are calls for scrutiny and讨论, not just passive sharing.

ImpactNeutral impact

Low to moderate perceived impact: several posts advocate for caution against misinformation and promote further discussion, but few claim clear real-world changes.

Abstract in brief

  • The study pooled data from six large cohort studies involving over 660,000 adults to examine how different levels of leisure time physical activity impact mortality risk, finding that increased activity generally lowers the risk of death.
  • Researchers identified that engaging in less than the recommended 75 MET-hours/week reduces mortality risk by about 20%, and doing 1-3 times the recommended amount further decreases risk, with the greatest benefit observed at 3-5 times the recommendation.
  • The findings suggest there is an upper limit to mortality benefits from physical activity at approximately 3 to 5 times the minimum recommended amount, beyond which additional activity does not significantly improve mortality outcomes.]

Top posts

Most liked on X and Bluesky
dranatomikrobiyoloji
@dranatomikro · X

@OdakTV1 Arkadaşım, ufak bir araştırmayla hangi tiplerin safsata yayma derdinde olduğunu anlayabilirsiniz. Ama doğrular tıklanmıyor, bu saçmalıklar etkileşim getiriyor diye ısrarla bu tipelri önümüze düşürüyüorsunuz. Bak geçen de benzer bişey yapmıştın. Cidden soruyorum, bu yaptığın etik

Apr 5, 2026 · 124 likes · 7 shares · 23,463 followers View post →
Dr Dawn Arda
@DawnArda · X

Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers, there’s strong evidence that #exercise reduces the risk by as much as 25-30%. The more we exercise, the lower our risk.

May 3, 2022 · 98 likes · 12 shares · 8,162 followers View post →
dranatomikrobiyoloji
@dranatomikro · X

@esreflarsenn Arkadaşım, ufak bir araştırmayla hangi tiplerin safsata yayma derdinde olduğunu anlayabilirsiniz. Ama doğrular tıklanmıyor, bu saçmalıklar etkileşim getiriyor diye ısrarla bu tipelri önümüze düşürüyüorsunuz. Bak geçen de benzer bişey yapmıştın. Cidden soruyorum, bu yaptığın etik

Apr 5, 2026 · 53 likes · 4 shares · 23,463 followers View post →
dranatomikrobiyoloji
@dranatomikro · X

Bu konuda artık susmayacağım. Çünkü sporla alakalı bilmeden yapacağınız her yorum, gelecek nesilleri dahi etkileyecek ciddi dezenformasyona sebep olacak. Meslektaşımsa meslektaşım. Bu kadar içi boş, havada kalmış, halk ağzıyla yapılan bir yorumu kabul edemem ve cevabını veririm. https://t.co/tIv5lCgJDC

Apr 5, 2026 · 47 likes · 5 shares · 23,463 followers View post →
Beth Frates MD
@BethFratesMD · X

Please join us for the next Harvard Lifestyle Medicine Journal Club. January 14, 2026--Wednesday 12:00 pm Noon EST Dr. Meagan Wasfy, a renowned cardiologist at Mass General Hospital, will talk about "Examining the Dose Response Between Physical Activity and Long-Term Health." https://t.co/7V9OFCH2Tm

Jan 13, 2026 · 19 likes · 5 shares · 154,138 followers View post →
Agingdoc
@agingdoc1 · X

Leisure Time Physical Activity and Mortality A Detailed Pooled Analysis of the Dose-Response Relationship Compared with those reporting no leisure time PA, they observed 20% ⬇️ mortality risk among those performing less than the recommended minimum. https://t.co/x0EUv1I8SY

Sep 10, 2022 · 8 likes · 3 shares · 42,833 followers View post →

All mentions

Longevety or Bullshit ?
@Longevity_or_BS · X

Sources (cont.): • NHS, "Physical activity guidelines for adults aged 19 to 64" ("if you can still talk, but https://t.co/e3i2NRGtq2 • Arem et al., pooled analysis of 6 studies, 661,137 adults in the US and Europe followed fo https://t.co/NTexDug7O8

Oct 18, 2026 · 1 followers View post →
tota
@totajapan · X

適度な運動は健康に良いが、非常に運動量が多くても、健康に良くないという訳ではなさそうです。 ただし、運動量が多くなればなるほど健康に良い、という訳でもありません。 https://t.co/zYBxq2P4r1

Oct 12, 2026 · 104 followers View post →
Joshua Vecchio
@Joshua_Vecchio · X

https://t.co/eFucjVVpxA

Oct 10, 2026 · 2 likes · 3 followers View post →
Wyatt Miller
@wyxmil · X

Source: https://t.co/eHspr6jJZJ

Sep 4, 2026 · 1,690 followers View post →
Forge & Flag
@forgeandflag · X

The world will spend hundreds of billions chasing longer life, yet the intervention with the strongest human evidence is free: your own legs. The longevity economy is scaling fast. The broad longevity market sits near $28B in 2025 and is projected to reach $67B by 2035 [1], https://t.co/fn1FqyWfOR

Jul 6, 2026 · 6 followers View post →
dranatomikrobiyoloji
@dranatomikro · X

Bu konuda artık susmayacağım. Çünkü sporla alakalı bilmeden yapacağınız her yorum, gelecek nesilleri dahi etkileyecek ciddi dezenformasyona sebep olacak. Meslektaşımsa meslektaşım. Bu kadar içi boş, havada kalmış, halk ağzıyla yapılan bir yorumu kabul edemem ve cevabını veririm. https://t.co/tIv5lCgJDC

Apr 5, 2026 · 47 likes · 5 shares · 23,463 followers View post →
dranatomikrobiyoloji
@dranatomikro · X

@OdakTV1 Arkadaşım, ufak bir araştırmayla hangi tiplerin safsata yayma derdinde olduğunu anlayabilirsiniz. Ama doğrular tıklanmıyor, bu saçmalıklar etkileşim getiriyor diye ısrarla bu tipelri önümüze düşürüyüorsunuz. Bak geçen de benzer bişey yapmıştın. Cidden soruyorum, bu yaptığın etik

Apr 5, 2026 · 124 likes · 7 shares · 23,463 followers View post →
dranatomikrobiyoloji
@dranatomikro · X

@esreflarsenn Arkadaşım, ufak bir araştırmayla hangi tiplerin safsata yayma derdinde olduğunu anlayabilirsiniz. Ama doğrular tıklanmıyor, bu saçmalıklar etkileşim getiriyor diye ısrarla bu tipelri önümüze düşürüyüorsunuz. Bak geçen de benzer bişey yapmıştın. Cidden soruyorum, bu yaptığın etik

Apr 5, 2026 · 53 likes · 4 shares · 23,463 followers View post →
Beth Frates MD
@BethFratesMD · X

Please join us for the next Harvard Lifestyle Medicine Journal Club. January 14, 2026--Wednesday 12:00 pm Noon EST Dr. Meagan Wasfy, a renowned cardiologist at Mass General Hospital, will talk about "Examining the Dose Response Between Physical Activity and Long-Term Health." https://t.co/7V9OFCH2Tm

Jan 13, 2026 · 19 likes · 5 shares · 154,138 followers View post →
HealthElysium
@XHealthElysium · X

Scientific References: Blood Pressure Cornelissen, V. A., & Fagard, R. H. (2005). Effects of endurance training on blood pressure: a meta-analysis. Hypertension, 46(4), 667–675. https://t.co/nRhp76pSry Adiposity (Body Fat) Ross, R., et al. (2000). Reduction in obesity and

Jun 30, 2025 · 2 followers View post →
Jasmine Feliciano
@therealjasfel · X

All of this depends on your health, so consult with your physician, and think about getting a tracker that has a heart rate monitor. Don't forget to prioritize recovery and balance. Your body will thank you!

Jun 8, 2024 · 1 like · 2 followers View post →
Dr Cailbhe Doherty
@cailbhe.bsky.social · Bluesky

Can you exercise too much? Studies suggest that extreme exercise doesn't significantly raise mortality risks compared to moderate levels. Full video here: youtu.be/7WWZ3XswLkY

Dec 6, 2023 · 2 likes View post →
Dr Cailbhe Doherty
@DohertyCailbhe · X

Can you exercise too much? Studies suggest that extreme exercise doesn't significantly raise mortality risks compared to moderate levels. Full video here: https://t.co/4f47tvWZMS https://t.co/BPpnZim9PY

Dec 6, 2023 · 3 likes · 780 followers View post →
Leonel Díaz González
@LeoDiazGlez · X

La polémica nace de un artículo del JAMA de 2015 en el que se apunta una posible curva en J en cuanto al ejercicio. doi:10.1001/jamainternmed.2015.0533 Según este paper el efecto deletéreo aparece a partir de 10x las recomendaciones de ejercicio para población americana. https://t.co/rxhs7LSrxx

Jul 5, 2023 · 5 likes · 499 followers View post →
Zaida Hurtado
@HurtadoZaidaa · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

Jun 7, 2023 · 12 shares · 4,692 followers View post →
Psychology Fanatic
@FLsociety · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

Jan 28, 2023 · 12 shares · 2,665 followers View post →
Luke Neumann
@pglukeneumann · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

Jan 28, 2023 · 12 shares · 317 followers View post →
Dr Dawn Arda
@DawnArda · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

Jan 28, 2023 · 12 shares · 8,162 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Leisure Time Physical Activity and Mortality A Detailed Pooled Analysis of the Dose-Response Relationship Compared with tho…

Sep 11, 2022 · 3 shares · 131 followers View post →
לורנס וורגרייב
@Eyaldg · X

RT @agingdoc1: Leisure Time Physical Activity and Mortality A Detailed Pooled Analysis of the Dose-Response Relationship Compared with tho…

Sep 10, 2022 · 3 shares · 1,191 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @agingdoc1: Leisure Time Physical Activity and Mortality A Detailed Pooled Analysis of the Dose-Response Relationship Compared with tho…

Sep 10, 2022 · 3 shares · 1,364 followers View post →
Agingdoc
@agingdoc1 · X

Leisure Time Physical Activity and Mortality A Detailed Pooled Analysis of the Dose-Response Relationship Compared with those reporting no leisure time PA, they observed 20% ⬇️ mortality risk among those performing less than the recommended minimum. https://t.co/x0EUv1I8SY

Sep 10, 2022 · 8 likes · 3 shares · 42,833 followers View post →
asghar Ansari
@MAsghar20338812 · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 21, 2022 · 12 shares · 427 followers View post →
Glenn Hutton2
@GlennHutton2 · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 12, 2022 · 12 shares · 1,339 followers View post →
Paul Gowell
@GowellPaul · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 9, 2022 · 12 shares · 72,595 followers View post →
kharidtha
@karidtha · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 8, 2022 · 12 shares · 1,167 followers View post →
Christopher Copas✍
@C_B_Copas · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 8, 2022 · 12 shares · 3,287 followers View post →
Judy Joy Ⓥ♡
@judy_tweets · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 3, 2022 · 12 shares · 1,364 followers View post →
Pragnani
@pragnani · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 3, 2022 · 12 shares · 1,493 followers View post →
TAKE (花鳥風月 時々Bike)
@monster636ninja · X

RT @DawnArda: Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers,…

May 3, 2022 · 12 shares · 26,612 followers View post →
Dr Dawn Arda
@DawnArda · X

Studies show that being physically active reduces the risk of several types of #cancer. For breast, colon and womb cancers, there’s strong evidence that #exercise reduces the risk by as much as 25-30%. The more we exercise, the lower our risk.

May 3, 2022 · 98 likes · 12 shares · 8,162 followers View post →
Ivor Goodbody
@IvorGoodbody · X

@nickengerer It was because of considerations like this that I decided long ago to run up to ~4 hours a week - and daily depending on rain - but not to marathon, ironman or ultra-anything! https://t.co/trdokut2bW + https://t.co/Uq6UEylPYr

Mar 5, 2021 · 1 like · 1,888 followers View post →
kayu
@kayu464 · X

@iena_7716 がんリスクも50%下げますし、記憶力もアップします☺️ Leisure Time Physical Activity and Mortality:A Detailed Pooled Analysis of the Dose-Response Relationship (運動と死亡率の関係のグラフの元論文です) https://t.co/R0VI1mmTlU

Aug 14, 2020 · 2 likes · 834 followers View post →
koureiigaku
@koureiigaku · X

余暇時間における身体活動と死亡との用量反応関係を評価した別の研究*のプール解析でも、同程度の身体活動量で31~37%の死亡リスク低下が報告されていました。 https://t.co/LvhMaT5Yq0

Sep 2, 2019 · 1 like · 851 followers View post →
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JAMA Intern Med. 2015 Jun;175(6):959-67. doi: 10.1001/jamainternmed.2015.0533.Leisure time physical activity and mortality: a detailed ...

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Combining weight training with cardio for weight loss - Facebook
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JAMA Intern Med. 2015;175(6):959‐967. doi: 10.1001/jamainternmed.2015.0533 Gebel K, Ding D, Chey T, Stamatakis E, Brown WJ, Bauman AE ...

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"The sweet spot for exercise benefits, however, came among those ...
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JAMA Intern Med. 2015 Jun;175(6):959-67. doi: 10.1001/jamainternmed.2015.0533.Leisure time physical activity and mortality: a detailed ...

Feb 18, 2016 View →
All levels of physical activity found to postpone mortality - Healio
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JAMA Intern Med. 2015;doi:10.1001/jamainternmed.2015.0533. Healio AI. Ask a clinical question and tap into Healio AI's knowledge base. PubMed ...

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