Drug Alcohol Depend July 2015 PMID 25986964

Brain and cognition abnormalities in long-term anabolic-androgenic steroid users.

Marc J Kaufman, Amy C Janes, James I Hudson, Brian P Brennan, Gen Kanayama, Andrew R Kerrigan, J Eric Jensen, Harrison G Pope

Mentions

19
Peak: 1 in Jan 2021
across 5 sources since Jan 2021

Extended reach

39,261
potential audience

Total likes

2,726

Video views

29,181

Mentions per month

Jan 2021 – Jul 2025

Where it's discussed

  • X / Twitter5 posts
  • Reddit5 posts
  • News5 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The overall tone reflects moderate agreement, as some posts directly mention the link between steroids and psychiatric symptoms, like increased aggression and cognitive issues, using phrases such as 'associated with' and 'idea.' The short comments and mentions of related thoughts demonstrate a basic level of interest and engagement, but without deep analysis or extensive discussion of methodology or implications.

AgreementModerate agreement

Most discussions acknowledge and summarize the findings of the publication, such as the link between long-term steroid use and cognitive or psychiatric effects.

InterestModerate interest

Participants show moderate interest, often sharing brief reactions or ideas related to the topic rather than deep analysis.

EngagementModerate engagement

Posts include some references to the article's implications, but mostly consist of short remarks, indicating moderate engagement.

ImpactModerate impact

The discussions suggest that the article prompts awareness or curiosity about steroid effects, though few indicate broad influence on attitudes or practices.

Abstract in brief

  • Long-term anabolic-androgenic steroid (AAS) use in men is linked to changes in brain structure and function, including larger right amygdala volume and reduced connectivity between this region and areas involved in cognition and emotion.
  • These brain alterations are associated with poorer performance on spatial memory tasks and changes in brain chemistry, such as increased glutamate turnover, which may heighten vulnerability to neurotoxic effects.
  • Overall, chronic AAS use may contribute to psychiatric symptoms like increased aggression and cognitive difficulties by affecting brain regions responsible for emotional regulation and cognitive control.]

Top posts

Most liked on X and Bluesky
William Lagakos
@caloriesproper2 · X

Brain and cognition abnormalities in long-term anabolic-androgenic steroid users https://t.co/baf0J2dffM

Apr 11, 2025 · 2 likes · 3,067 followers View post →
ID: Black American
@DreamBi35064054 · X

@Claudiogambla @Maratea20G @SeaHorseNation3 @travelamigo @Cernovich https://t.co/nSFyDpHw8Y

Jan 3, 2021 · 1 like · 350 followers View post →
Ontja Huscarlnäherin
@OntjaH · X

@boricuabc2 Just an idea... Anabolic-androgenic steroid (AAS) use is associated with psychiatric symptoms including increased aggression as well as with cognitive dysfunction. https://t.co/1zeMYXZRH5 https://t.co/KjPfruhlap

May 8, 2024 · 4,301 followers View post →
Y
@EARhye · X

Brain and Cognition Abnormalities in Long-Term Anabolic-Androgenic Steroid Users Anabolic-androgenic steroid (AAS) use is associated with psychiatric symptoms including increased aggression as well as with cognitive dysfunction. https://t.co/JcYdSNOPVE https://t.co/R35E8ru5Oa

Jul 29, 2025 · 1,842 followers View post →

All mentions

Y
@EARhye · X

Brain and Cognition Abnormalities in Long-Term Anabolic-Androgenic Steroid Users Anabolic-androgenic steroid (AAS) use is associated with psychiatric symptoms including increased aggression as well as with cognitive dysfunction. https://t.co/JcYdSNOPVE https://t.co/R35E8ru5Oa

Jul 29, 2025 · 1,842 followers View post →
William Lagakos
@caloriesproper2 · X

Brain and cognition abnormalities in long-term anabolic-androgenic steroid users https://t.co/baf0J2dffM

Apr 11, 2025 · 2 likes · 3,067 followers View post →
Scott Hughes
@Brxx777 · X

@LangmanVince "Brain and Cognition Abnormalities in Long-Term Anabolic-Androgenic Steroid Users" https://t.co/zDeK2mVTlj

Oct 30, 2024 · 521 followers View post →
Ontja Huscarlnäherin
@OntjaH · X

@boricuabc2 Just an idea... Anabolic-androgenic steroid (AAS) use is associated with psychiatric symptoms including increased aggression as well as with cognitive dysfunction. https://t.co/1zeMYXZRH5 https://t.co/KjPfruhlap

May 8, 2024 · 4,301 followers View post →
ID: Black American
@DreamBi35064054 · X

@Claudiogambla @Maratea20G @SeaHorseNation3 @travelamigo @Cernovich https://t.co/nSFyDpHw8Y

Jan 3, 2021 · 1 like · 350 followers View post →