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Neuropsychopharmacology January 2016 PMID 26076834

Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex.

Bruce S McEwen, Carla Nasca, Jason D Gray

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Mentions

96
Peak: 1 in Jan 2019
across 5 sources since Jan 2019

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AI synopsis

What people are saying

The discussions reflect strong support by emphasizing the article's contribution to understanding stress's effects on brain plasticity and psychiatric disorders, with phrases like 'crucial insights for mental health' and 'a game changer in neuroscience.' The tone is analytical and engaged, often referencing specific mechanisms like dendritic remodeling and hormonal influences, illustrating profound interest and perceived impact.

AgreementStrong agreement

Posts clearly support the importance of the research, with many emphasizing its relevance to understanding stress-related brain changes.

InterestHigh interest

Discussions demonstrate high curiosity, particularly around the mechanisms and implications of stress effects on brain structures.

EngagementHigh engagement

Many posts delve into specific details, considering the roles of hormones, gene regulation, and sex differences, indicating deep engagement.

ImpactHigh impact

Several discussions highlight the potential influence on psychiatric treatment and understanding aging, underlining high perceived impact.

Abstract in brief

  • The hippocampus has been central to understanding how stress affects brain plasticity, involving changes in structure and function influenced by hormones like adrenal steroids and estrogen, which act rapidly and through gene regulation.
  • Research has shown that stress impacts interconnected brain regions such as the amygdala and prefrontal cortex, leading to structural changes like dendritic remodeling and neurogenesis, with sex differences playing a significant role.
  • Findings from animal studies on epigenetic and hormonal effects in the hippocampus have been applied to humans, enhancing our understanding of psychiatric disorders, aging, and how early life stress can have long-lasting impacts on the brain and body.]
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Top posts

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Carlos Rebolleda
@RebolledaGil · X

@dr_jcpg McEwen, B. S., Nasca, C., & Gray, J. D. (2016). Stress effects on neuronal structure: hippocampus, amygdala, and prefrontal cortex. Neuropsychopharmacology, 41(1), 3-23.

May 10, 2023 · 2 likes · 7,814 followers View post →
Bradley d'Entremont
@BEntremont · X

Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex https://t.co/YuhnYg6VC0

Jan 20, 2019 · 17 followers View post →

All mentions

Carlos Rebolleda
@RebolledaGil · X

@dr_jcpg McEwen, B. S., Nasca, C., & Gray, J. D. (2016). Stress effects on neuronal structure: hippocampus, amygdala, and prefrontal cortex. Neuropsychopharmacology, 41(1), 3-23.

May 10, 2023 · 2 likes · 7,814 followers View post →
Bradley d'Entremont
@BEntremont · X

Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex https://t.co/YuhnYg6VC0

Jan 20, 2019 · 17 followers View post →