Obes Rev October 2015 PMID 26098597

Argument for a non-linear relationship between severity of human obesity and dopaminergic tone.

A Horstmann, W K Fenske, M K Hankir

Mentions

16
Peak: 5 in Feb 2024
across 4 sources since Jul 2018

Extended reach

301,692
potential audience

Total likes

5,967

Video views

259,187

Mentions per month

Jul 2018 – Nov 2025

Where it's discussed

  • X / Twitter7 posts
  • News5 articles
  • YouTube2 videos
  • TikTok2 posts

AI synopsis

What people are saying

The analysis reflects a balance of curiosity and skepticism in the social discussions, with posts mentioning dieting approaches like keto and linking them to cravings, alongside references to neurobiological factors and research corrections. Words like 'proof,' 'implications,' and mentions of specific studies reveal a moderate level of engagement and interest, while the tone remains somewhat cautious about fundamental claims made in the publication.

AgreementNeither agree nor disagree

The discussions show mixed opinions; some posts support the idea that diet and neurobiology are linked to obesity, while others are cautious or neutral.

InterestModerate interest

Posts demonstrate moderate interest by focusing on diet impacts and neurochemical aspects, but not all delve deeply into the scientific details.

EngagementModerate engagement

Discussions include sharing personal experiences with dieting and referencing specific studies, indicating some level of active engagement.

ImpactNeutral impact

The conversations touch on implications for dieting strategies and understanding obesity, but overall influence on broader scientific or policy debates appears limited.

Abstract in brief

  • The text discusses how changes in dopamine systems are linked to obesity in both animals and humans, but the exact nature of this relationship is unclear and has shown mixed results in studies.
  • It proposes a new model suggesting a nonlinear, quadratic relationship between dopamine function and obesity, driven by shifts in overall dopaminergic tone and phasic signaling, which could explain the conflicting findings.
  • The model helps to understand various obesity-related behaviors, such as altered food reward responses, decision-making differences, and cognitive performance, by integrating molecular and behavioral data into a unified framework.

Top posts

Most liked on X and Bluesky
Kevin Hall
@KevinH_PhD · X

Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI results and may have implications for theories about D2BP and obesity such as what is described here: https://t.co/K43MA9xTxg

May 6, 2022 · 18 likes · 2 shares · 38,765 followers View post →
blubber_bones
@blubber_bones · X

https://t.co/T8Iw70kvbw One of the main reasons I do keto is because it reduces cravings not just physical hunger but the mental cravings to want junk food or other pleasurable activities in the long run I'm feel less anxiously searching for something when I'm on a low...

Feb 23, 2024 · 1,105 followers View post →
blubber_bones
@blubber_bones · X

The WORST Diet for Belly Fat - Confirmed by MRI Scan in New Study https://t.co/CJ9VcseigJ

Feb 23, 2024 · 1,105 followers View post →
Valerie L. Darcey, PhD, MS, RD
@vdarcey · X

RT @KevinH_PhD: Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI r…

May 6, 2022 · 2 shares · 989 followers View post →
Aletheia
@Veritas_Sky · X

Study proves that carbohydrates cause food addiction especially in the obese. https://t.co/q689ak23JG

Feb 23, 2024 · 245 followers View post →
A Sheppard
@Danette135 · X

RT @KevinH_PhD: Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI r…

May 7, 2022 · 2 shares · 209 followers View post →

All mentions

WalkSprint_Jump
@WalkSprint_Jump · X

The WORST Diet for Belly Fat - Confirmed by MRI Scan in New Study https://t.co/xloTHRknjD via @YouTube

Feb 24, 2024 · 6 followers View post →
blubber_bones
@blubber_bones · X

https://t.co/T8Iw70kvbw One of the main reasons I do keto is because it reduces cravings not just physical hunger but the mental cravings to want junk food or other pleasurable activities in the long run I'm feel less anxiously searching for something when I'm on a low...

Feb 23, 2024 · 1,105 followers View post →
blubber_bones
@blubber_bones · X

The WORST Diet for Belly Fat - Confirmed by MRI Scan in New Study https://t.co/CJ9VcseigJ

Feb 23, 2024 · 1,105 followers View post →
Aletheia
@Veritas_Sky · X

Study proves that carbohydrates cause food addiction especially in the obese. https://t.co/q689ak23JG

Feb 23, 2024 · 245 followers View post →
A Sheppard
@Danette135 · X

RT @KevinH_PhD: Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI r…

May 7, 2022 · 2 shares · 209 followers View post →
Valerie L. Darcey, PhD, MS, RD
@vdarcey · X

RT @KevinH_PhD: Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI r…

May 6, 2022 · 2 shares · 989 followers View post →
Kevin Hall
@KevinH_PhD · X

Even though the main results in our 2014 paper were relatively unaffected, correcting the software error affected the ROI results and may have implications for theories about D2BP and obesity such as what is described here: https://t.co/K43MA9xTxg

May 6, 2022 · 18 likes · 2 shares · 38,765 followers View post →
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Nov 17, 2025 View →
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