PubHawk
Open Heart June 2015 PMID 26113985

Capsaicin may have important potential for promoting vascular and metabolic health.

Mark F McCarty, James J DiNicolantonio, James H O'Keefe

Download social card

Mentions

45
Peak: 3 in Jul 2020
across 6 sources since May 2017

Extended reach

468,721
potential audience

Total likes

719

Video views

41,238

Mentions per month

May 2017 – Dec 2025

Where it's discussed

  • Facebook19 posts
  • News11 articles
  • X / Twitter7 posts
  • Instagram5 posts
  • YouTube2 videos
  • Reddit1 posts

AI synopsis

What people are saying

The discussions highlight the promising effects of capsaicin on health, with posts referencing studies and mentioning benefits like anti-inflammatory effects, indicating interest and agreement. The tone is moderately engaged and recognizes potential applications, but lacks detailed critical analysis or wide-reaching implications, leading to moderate impact scores.

AgreementModerate agreement

Most discussions acknowledge the potential health benefits of capsaicin based on scientific references and positive tone, showing general agreement with the publication.

InterestModerate interest

Participants express moderate interest, with some mention of practical benefits like anti-inflammatory effects and applications in injury recovery.

EngagementModerate engagement

Discussions loosely reference the research and share personal experiences, indicating some engagement but limited deep analysis.

ImpactModerate impact

The conversations suggest a recognition of capsaicin's potential, but without strong calls for clinical application or societal change, impacts are seen as moderate.

Abstract in brief

  • Capsaicin, the compound responsible for the spiciness of peppers, can positively influence vascular and metabolic health by activating TRPV1 receptors found in various tissues, leading to benefits like improved blood vessel function and cholesterol management.
  • Activation of TRPV1 by capsaicin increases calcium influx, which stimulates production of protective proteins such as eNOS, UCP2, and antioxidant enzymes, reducing inflammation and oxidative stress, thereby supporting cardiovascular health and combating metabolic disorders.
  • Studies in rodents and humans suggest that dietary capsaicin can enhance metabolism, promote fat burning, and improve conditions like obesity, diabetes, fatty liver disease, and hypertension, with potential for clinical uses like increasing exercise capacity through topical applications.
Read the full abstract

Top posts

Most liked on X and Bluesky
James DiNicolantonio
@drjamesdinic · X

@JWLevitt @smartflexx Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 4 likes · 1 share · 208,331 followers View post →
James DiNicolantonio
@drjamesdinic · X

@Dr_Imran_Malik Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 1 like · 208,331 followers View post →
Carol
@mywordsworlds1 · X

https://t.co/y1vgdtoIRh

Oct 12, 2024 · 5,259 followers View post →
TammyLongWind
@TammyLongWind · X

Unbelievable Benefits of Cayenne Pepper That Will Blow Your Mind! Herb o... https://t.co/pfsg6zJ8U6 via @YouTube 1 capsule taken as of today 500 mg’s , feelin the anti inflammatory effects on my muscular system , serious shoulder injury

May 19, 2023 · 2,996 followers View post →
Raj Makhija
@iRajMakhija · X

RT @drjamesdinic: @JWLevitt @smartflexx Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 1 share · 1,929 followers View post →
Rebecca Hibbs
@RebeccaHibbs4 · X

Capsaicin, the phytochemical responsible for the spiciness of peppers, has potential to modulate metabolism via activation of transient receptor potential TRPV1 receptors, which are found on nociceptive sensory neurons, but and a range of other tissues. https://t.co/l41gEGl7dv

Sep 2, 2023 · 208 followers View post →

All mentions

Carol
@mywordsworlds1 · X

https://t.co/y1vgdtoIRh

Oct 12, 2024 · 5,259 followers View post →
AIBannedForTruth
@SumWun86290357 · X

@rbfitzweld2 @stopvaccinating I notice you didn't link anything, nor did you refute anything I said. Here's an example of a published paper that has reference links to studies. https://t.co/Ts4pLS97ZD Capsaicin may have important potential for promoting vascular and metabolic health

Dec 31, 2023 · 65 followers View post →
Rebecca Hibbs
@RebeccaHibbs4 · X

Capsaicin, the phytochemical responsible for the spiciness of peppers, has potential to modulate metabolism via activation of transient receptor potential TRPV1 receptors, which are found on nociceptive sensory neurons, but and a range of other tissues. https://t.co/l41gEGl7dv

Sep 2, 2023 · 208 followers View post →
TammyLongWind
@TammyLongWind · X

Unbelievable Benefits of Cayenne Pepper That Will Blow Your Mind! Herb o... https://t.co/pfsg6zJ8U6 via @YouTube 1 capsule taken as of today 500 mg’s , feelin the anti inflammatory effects on my muscular system , serious shoulder injury

May 19, 2023 · 2,996 followers View post →
Raj Makhija
@iRajMakhija · X

RT @drjamesdinic: @JWLevitt @smartflexx Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 1 share · 1,929 followers View post →
James DiNicolantonio
@drjamesdinic · X

@JWLevitt @smartflexx Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 4 likes · 1 share · 208,331 followers View post →
James DiNicolantonio
@drjamesdinic · X

@Dr_Imran_Malik Capsaicin https://t.co/idcb6bmAdr

Jul 12, 2020 · 1 like · 208,331 followers View post →
casalferver
Facebook

org/10.5935/1984-6835.20120012; https://doi.org/10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades ...

Dec 12, 2025 View →
مترجم علاج السمنة جيمس دي نيكولانتونيو سييم لاند 1 241005 175655 ...
News

‫‪https://doi.org/10.1136/openhrt-2020-001356‬‬ ‫]‪[64‬‬ ‫‪Popkin, BM, Du, S‬‬ ... 2015-000262 ‫]‪[295‬‬ ‫‪Hu, Y., Ehli, EA, Kittelsrud, J., Ronan, PJ‬‬ ...

Dec 12, 2025 View →
Capsaicin May Have Important Potential For Promoting Vascular ...
News

doi:10.1136/openhrt-2015-000262. Open Heart muscle cells, broblasts ... doi:10.1136/openhrt-2015-000262. Open Heart 5. 6. 7. 8. 9. 10. 11. 12. 13. 14 ...

Dec 12, 2025 View →
Duranova2021 Article ChiliPeppersCapsicumSppTheSpic | PDF
News

Open Heart 2:e000262. https://doi.org/ hamsters. Eur J Nutr 52:379–388. https://doi.org/10.1007/ 10.1136/openhrt-2015-000262 s00394-012-0344-2 Mendivil EJ ...

Dec 12, 2025 View →
The Obesity Fix - James DiNicolantonio | PDF | Body Mass Index ...
News

metabolic health: Table 1. Open Heart, 2(1), e000262. https://doi.org/10.1136/openhrt-2015-000262 [295] Hu, ...

Dec 12, 2025 View →
Good Gut A-Z by Married To Health | PDF
News

jalapeno. https://doi.org/10.1136/openhrt-2015-000262. 3. Spice Up Your Life: The Health Benefits of Spicy Foods.

Dec 12, 2025 View →
2.+7102 Article+Text 28456 - 143 151 | PDF | Digestion | Indigestion
News

important potential for promoting vascular and metabolic health. Open Heart, 2(1), p. e000262. Available at: https://doi.org/10.1136/openhrt-2015-000262.

Dec 12, 2025 View →
Blood Supply of Heart . for mor information check . www ...
Facebook

Blood Supply of Heart ✓ . for mor information check . www.drmuhammedziya.com . Like and share my new page Doctor 4 all . stay tuned for new ...

Dec 4, 2025 View →
What Happens to Your Body When You Take Immunity Shots ...
News

Open Heart. 2015;2(1):e000262. doi:10.1136/openhrt-2015-000262. Johnston M, McBride M, Dahiya D, et al. Antibacterial activity of Manuka ...

Nov 29, 2025 View →
Hoje é Valentine's Day nos EUA, mas o Brasil tem ... - Facebook
Facebook

... 10.1136/openhrt-2015-000262⁣ #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Aug 12, 2025 View →
Hoje é Valentine's Day nos EUA, mas o Brasil tem ... - Facebook
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Jul 23, 2025 View →
E já que hoje é Dia dos Namorados, separei alguns alimentos que ...
Facebook

org/10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Jun 12, 2025 View →
E já que hoje é Dia dos Namorados, separei alguns ... - Facebook
Facebook

... 10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Jun 12, 2025 View →
Dr. Barakat - Dr. Barakat added a new photo — in Brazil. - Facebook
Facebook

org/10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Jun 11, 2025 View →
1kg de gordura e 1kg de músculo pesam a mesma coisa ... - Facebook
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

May 2, 2025 View →
Há quem pense que o consumo de proteína seja ... - Facebook
Facebook

org/10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Mar 5, 2025 View →
5 Healthiest Spices to Always Keep in Your Pantry
News

Open Heart. 2015 Jun 17;2(1):e000262. doi: 10.1136/openhrt-2015-000262.

Feb 25, 2025 View →
Contagem regressiva para transformar sua saúde! Em 3 dias ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Jan 17, 2025 View →
Is Chili Healthy? Yes, But Here's How RDs Make It Healthier
News

Open Heart. 2015 Jun 17;2(1):e000262. doi: 10.1136/openhrt-2015-000262. PMID: 26113985; PMCID: PMC4477151. Alam Khan, Mahpara Safdar ...

Jan 10, 2025 View →
Dr. - Apenas 10 semanas de musculação podem transformar a ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Oct 18, 2024 View →
Bom dia, Constelação! Começando a semana com esse vídeo ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Jul 22, 2024 View →
Dr. Barakat - Dr. Barakat added a new photo — in Brazil. - Facebook
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

May 27, 2024 View →
Você passa o dia no smartphone? Talvez, seja hora de repensar ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Apr 4, 2024 View →
Dr. Barakat - Dr. Barakat added a new photo — in Brazil. - Facebook
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Feb 22, 2024 View →
7 Healthy Foods That Can Give You an Upset Stomach After Eating
News

doi:10.1136/openhrt-2015-000262. Sánchez-Pérez S, Comas-Basté O, Rabell-González J, Veciana-Nogués MT, Latorre-Moratalla ML, Vidal-Carou MC ...

Aug 25, 2023 View →
Dr. Paulo Howard updated their cover photo. - Facebook
Facebook

org/10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Apr 26, 2023 View →
A fórmula do Insuglico contém uma exclusiva fórmula com ...
Instagram

... 10.1136/openhrt-2015-000262. BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Jan 26, 2023 View →
Centro Bert Hellinger: Psicoterapia y Constelaciones Familiares ...
Facebook

Open Heart, 2(1), e000262. DOI: 10.1136/openhrt-2015-000262 · Revisa los beneficios de la capsaicina más allá del peso, centrándose en la ...

Oct 24, 2022 View →
Aqui estão alguns alimentos que aumentam a libido e ... - Instagram
Instagram

... //doi.org/10.5935/1984-6835.20120012; https://doi.org/10.1136/openhrt-2015-000262⁣ Créditos: @doutorbarakat ".

Sep 6, 2022 View →
⁣Hoje é o #DiaDoSexo (segurem a 5ª série que existe ... - Instagram
Instagram

... 10.1136/openhrt-2015-000262⁣ #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel⁣".

Sep 6, 2022 View →
Hoje é o #DiaDoSexo (segurem a 5ª série que existe dentro de ...
Instagram

... 10.1136/openhrt-2015-000262 BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Sep 6, 2021 View →
Dr. Barakat - CRM SP 68874 | Como o próprio nome já indica, o JI ...
Instagram

... 10.1136/openhrt-2015-000262. BASSO, Marina Rosana. Alimentos afrodisíacos: mitos, ritos, crenças e verdades. 2004. 119 f. Monografia ...

Oct 24, 2019 View →
Dr. Barakat - Diferentemente do que muitos possam achar, os ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Aug 6, 2018 View →
How to Stop a Heart Attack: Prevention, When Alone, and More
News

https://doi.org/10.1136/openhrt-2015-000262; Treatment of a heart attack. (2018). http://www.heart.org/HEARTORG/Conditions/HeartAttack ...

Mar 7, 2018 View →
What is the verdict when it comes to hot sauce? : r/nutrition
Reddit

... for promoting vascular and metabolic health. Open Heart, 2(1), e000262. http://doi.org/10.1136/openhrt-2015-000262 · caitdrum. • 8y ago.

Dec 9, 2017 View →
Dr. Barakat - Como iniciei mais cedo, um dos primeiros benefícios ...
Facebook

org/10.1136/openhrt-2015-000262 #drbarakatlibido #drbarakat #libidofeminina #libidomasculina #libido #vidasexual #saude #vidasaudavel ...

Aug 17, 2017 View →