July 2015 PMID 26118927

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.

Carles Cantó, Keir J Menzies, Johan Auwerx

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Mentions

17
Peak: 2 in Feb 2021
across 5 sources since Feb 2021

Extended reach

14,413
potential audience

Total likes

28

Video views

531

Mentions per month

Feb 2021 – Nov 2023

Where it's discussed

  • News6 articles
  • X / Twitter4 posts
  • Facebook3 posts
  • Blogs3 articles
  • YouTube1 videos

AI synopsis

What people are saying

Participants discuss key concepts such as NAD+'s role in ATP production and its influence on mitochondrial and nuclear balance, using technical language that indicates both interest and engagement. The mention of pathways like sirtuins and enzymes like NAM reflects an understanding of cellular metabolism and hints at potential therapeutic impacts.

AgreementModerate agreement

Most discussions recognize the importance of NAD+ in energy metabolism and its connection to cellular functions, showing general agreement with the publication's themes.

InterestModerate interest

Comments reflect a moderate level of interest in understanding NAD+ and mitochondrial processes, with some posts expressing enthusiasm for learning more.

EngagementModerate engagement

Participants reference specific biological mechanisms like the electron transport chain and sirtuin activity, indicating active engagement.

ImpactModerate impact

The discussions suggest that the research could have meaningful implications for understanding diseases like diabetes and cancer, signifying moderate impact.

Abstract in brief

  • NAD is a crucial molecule that influences energy balance in cells by activating sirtuins and maintaining healthy mitochondria.
  • Recent research highlights how improving NAD levels can help treat diseases like diabetes and cancer by rewiring cell metabolism and enhancing cellular responses.
  • This review discusses how NAD metabolism connects energy status to cellular and organismal adjustments, opening doors for potential therapies.]

Top posts

Most liked on X and Bluesky
Dr. Hernández-Reyes, A. RD, MSc, PhD
@albertohdez · X

Este paper para seguir aprendiendo sobre su metabolismo es esencial (10.1016/j.cmet.2015.05.023)

Jan 21, 2023 · 2 likes · 2,026 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky "Overall, the ETC reduces O2 to water and NADH to NAD+ for the purpose of generating ATP."

Apr 5, 2021 · 1 like · 3,952 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky https://t.co/VijseaV9ng

Feb 28, 2021 · 3,952 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky "sirtuin activity is inhibited by NAM (Anderson et al., 2003), which could explain why NAM failed to provide the benefits of NA, however, in"

Feb 28, 2021 · 3,952 followers View post →

All mentions

Dr. Hernández-Reyes, A. RD, MSc, PhD
@albertohdez · X

Este paper para seguir aprendiendo sobre su metabolismo es esencial (10.1016/j.cmet.2015.05.023)

Jan 21, 2023 · 2 likes · 2,026 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky "Overall, the ETC reduces O2 to water and NADH to NAD+ for the purpose of generating ATP."

Apr 5, 2021 · 1 like · 3,952 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky https://t.co/VijseaV9ng

Feb 28, 2021 · 3,952 followers View post →
Rene Sugar
@renesugar · X

NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus https://t.co/nmpFBzF1Ky "sirtuin activity is inhibited by NAM (Anderson et al., 2003), which could explain why NAM failed to provide the benefits of NA, however, in"

Feb 28, 2021 · 3,952 followers View post →