Cell Rep July 2015 PMID 26146078

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic.

Vincent J Lynch, Oscar C Bedoya-Reina, Aakrosh Ratan, Michael Sulak, Daniela I Drautz-Moses, George H Perry, Webb Miller, Stephan C Schuster

Mentions

77
Peak: 3 in Mar 2025
across 6 sources since Sep 2018

Extended reach

10,317
potential audience

Total likes

69

Video views

2,804

Mentions per month

Sep 2018 – Mar 2025

Where it's discussed

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AI synopsis

What people are saying

Discussions highlight the significance of genes like TRPV3 in mammoth cold adaptation and explore possibilities of gene editing to replicate these traits in other species, with tone emphasizing scientific curiosity and potential breakthrough implications. References to specific genes, physiological mechanisms, and applications illustrate deep engagement with the subject matter.

AgreementModerate agreement

Most discussions recognize the significance of the research, with some references to genetic mutations and their role in adaptation, showing general support and alignment with the article's findings.

InterestHigh interest

The use of scientific terms like TRPV3, genetic differences, and gene editing indicates high curiosity and fascination with the research details.

EngagementModerate engagement

Participants are actively exploring mechanisms, potential applications such as gene editing, and linking related studies, demonstrating meaningful involvement.

ImpactModerate impact

The discourse suggests the research could influence future studies, conservation efforts, and biotechnology approaches, implying a moderate level of potential impact.

Abstract in brief

  • The study sequenced genomes of woolly mammoths and Asian elephants to find genetic differences that helped mammoths survive in cold Arctic environments, highlighting changes in genes related to hair, skin, fat, and temperature sensing.
  • Researchers identified specific genetic mutations in mammoths that are linked to their ability to adapt to extreme cold conditions, especially in functions like skin and hair development, fat storage, and sensing temperature.
  • They experimentally tested a key gene called TRPV3, which is involved in temperature sensation and hair growth, and found that a single mutation in mammoths significantly altered how this gene responds to temperature, helping them survive in icy climates.]

Top posts

Most liked on X and Bluesky
bioRxiv Published
@biorxiv_pubd · X

Elephantid genomes reveal the molecular bases of Woolly Mammoth adaptations to the arctic published as: https://t.co/HJepr1rzcI @cellreports #biorxiv

Dec 25, 2019 · 1 like · 2,908 followers View post →
David Castro
@DavidECastroG · X

Una comparación genética entre el mamut lanudo y el elefante asiático https://t.co/r1ZKe1kqwA mostró diferencias en al menos 1642 genes involucrados en la adaptación al frío extremo. ¿Se podría usar la edición genética para modificar esos genes del ADN del elefante asiático?

Mar 11, 2024 · 2,908 followers View post →
虚実歴史・漢字論・ナツメロ
@kyojitsurekishi · X

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic Cell Reports @CellPressNews https://t.co/b6P1gGXfgp

Mar 11, 2019 · 1,102 followers View post →
mike
@mike71715365973 · X

@Fynnderella1 The new whooly mouse model. TRPV3 Whooly Mammoth https://t.co/PRsStBkBvN TRPV1 Chikungunya virus / Heat Hypersensitivity https://t.co/pTeOexNF9A TRPV4 Enteric Coronaviruses https://t.co/Rch7mi1Msd '....TRPV4 plays an essential role in modulating calcium ion influx.'

Mar 10, 2025 · 298 followers View post →

All mentions

mike
@mike71715365973 · X

@Fynnderella1 The new whooly mouse model. TRPV3 Whooly Mammoth https://t.co/PRsStBkBvN TRPV1 Chikungunya virus / Heat Hypersensitivity https://t.co/pTeOexNF9A TRPV4 Enteric Coronaviruses https://t.co/Rch7mi1Msd '....TRPV4 plays an essential role in modulating calcium ion influx.'

Mar 10, 2025 · 298 followers View post →
mike
@mike71715365973 · X

@FrauHodl Cryo-Linking elephantids to mice: 1. TRPV3 / Wholly Mammoth https://t.co/PRsStBl9ll 2. Wholly Mice

Mar 5, 2025 · 298 followers View post →
David Castro
@DavidECastroG · X

Una comparación genética entre el mamut lanudo y el elefante asiático https://t.co/r1ZKe1kqwA mostró diferencias en al menos 1642 genes involucrados en la adaptación al frío extremo. ¿Se podría usar la edición genética para modificar esos genes del ADN del elefante asiático?

Mar 11, 2024 · 2,908 followers View post →
bioRxiv Published
@biorxiv_pubd · X

Elephantid genomes reveal the molecular bases of Woolly Mammoth adaptations to the arctic published as: https://t.co/HJepr1rzcI @cellreports #biorxiv

Dec 25, 2019 · 1 like · 2,908 followers View post →
虚実歴史・漢字論・ナツメロ
@kyojitsurekishi · X

Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic Cell Reports @CellPressNews https://t.co/b6P1gGXfgp

Mar 11, 2019 · 1,102 followers View post →