August 2016 PMID 26212172

Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome - A randomized, controlled, double-blind trial.

Jesus Castro-Marrero, Naia Sáez-Francàs, María Jose Segundo, Natalia Calvo, Mónica Faro, Luisa Aliste, Tomás Fernández de Sevilla, Jose Alegre

Mentions

35
Peak: 4 in Apr 2020
across 6 sources since Oct 2018

Extended reach

76,047
potential audience

Total likes

374

Video views

14,018

Mentions per month

Oct 2018 – Sep 2025

Where it's discussed

  • Facebook14 posts
  • X / Twitter8 posts
  • News6 articles
  • Blogs4 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions collectively recognize the study's evidence for CoQ10 and NADH reducing maximum heart rate in fatigued patients, with some users emphasizing personal or clinical importance. Words like 'help with tachycardia' and references to 'evidence' show a balance of interest and validation, while mentions of Long Covid and CFS demonstrate perceived real-world impact.

AgreementModerate agreement

Most discussions acknowledge the study's findings that supplementation can reduce maximum heart rate and fatigue, supporting the idea that CoQ10 and NADH may be beneficial.

InterestModerate interest

Participants show moderate interest, referencing both the scientific details and implications for conditions like Long Covid and CFS.

EngagementModerate engagement

Comments reflect active engagement with mentions of mechanisms, such as lower heart rates, and personal validation or skepticism, indicating thoughtful processing.

ImpactModerate impact

Discussions highlight potential clinical relevance, especially for symptom management in chronic conditions, suggesting a meaningful impact.

Abstract in brief

  • This study investigated whether taking Coenzyme Q10 plus NADH could help improve symptoms like fatigue and heart function in patients with Chronic Fatigue Syndrome (CFS).
  • The 8-week double-blind trial with 80 participants found that those taking the supplements had a lower maximum heart rate during exercise and reported less fatigue compared to a placebo group, though pain and sleep quality did not change significantly.
  • Overall, the supplementation appeared safe and potentially beneficial for reducing certain symptoms of CFS, but larger studies are needed to confirm these effects.]

Top posts

Most liked on X and Bluesky
It's ME(Jaime)
@exceedhergrasp1.bsky.social · Bluesky

Re: the heart palps specifically: pubmed.ncbi.nlm.nih.gov/26212172/

Apr 21, 2025 · 4 likes · 2 shares View post →
Peptide Sciences
@PeptideScience · X

CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenzyme Q10 and NAD+ on Maximum Heart Rate After Exercise Testing in Chronic Fatigue Syndrome - A Randomized, Controlled, Double-Blind Trial https://t.co/KPBoe3cQvq

Apr 22, 2020 · 3 likes · 3 shares · 6,722 followers View post →
Dr. Groysman, MD Long Covid Expert
@Covid_institute · X

#CFSME #LongCovid #LongCovidGroups One way to help with tachycardia. https://t.co/bBbRd9BprX

Dec 11, 2023 · 3 likes · 1 share · 484 followers View post →
Chillfrog - are you kidding me?
@DPhilvon · X

Von wegen das Zeug (Q10 & NADH) hat keine Evidenz bei #MECFS kann ich persönlich bestätigen. #CFS Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise … https://t.co/xKTBLxwM8P

Nov 5, 2022 · 1 like · 860 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

RT @PeptideScience: CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenz…

Apr 24, 2020 · 3 shares · 39,342 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @PeptideScience: CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenz…

Apr 24, 2020 · 3 shares · 6,543 followers View post →

All mentions

It's ME(Jaime)
@exceedhergrasp1.bsky.social · Bluesky

Re: the heart palps specifically: pubmed.ncbi.nlm.nih.gov/26212172/

Apr 21, 2025 · 4 likes · 2 shares View post →
Vital Reaction®
@h2vitalreaction · X

RT @Covid_institute: #CFSME #LongCovid #LongCovidGroups One way to help with tachycardia. https://t.co/bBbRd9BprX

Dec 13, 2023 · 1 share · 815 followers View post →
Dr. Groysman, MD Long Covid Expert
@Covid_institute · X

#CFSME #LongCovid #LongCovidGroups One way to help with tachycardia. https://t.co/bBbRd9BprX

Dec 11, 2023 · 3 likes · 1 share · 484 followers View post →
Chillfrog - are you kidding me?
@DPhilvon · X

Von wegen das Zeug (Q10 & NADH) hat keine Evidenz bei #MECFS kann ich persönlich bestätigen. #CFS Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise … https://t.co/xKTBLxwM8P

Nov 5, 2022 · 1 like · 860 followers View post →
Rene Sugar
@renesugar · X

Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome – A randomized, controlled, double-blind trial #MECFS #LongCovid https://t.co/CGHfDIwlwA

Apr 25, 2022 · 3,970 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @PeptideScience: CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenz…

Apr 24, 2020 · 3 shares · 6,543 followers View post →
م. محمد العقيلي
@MohdAlaqeili · X

RT @PeptideScience: CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenz…

Apr 24, 2020 · 3 shares · 3,262 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

RT @PeptideScience: CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenz…

Apr 24, 2020 · 3 shares · 39,342 followers View post →
Peptide Sciences
@PeptideScience · X

CoQ10 and NAD+ lower max heart rate after exercise in fatigued patients. NAD+ https://t.co/V9IBfkTRQJ Effect of Coenzyme Q10 and NAD+ on Maximum Heart Rate After Exercise Testing in Chronic Fatigue Syndrome - A Randomized, Controlled, Double-Blind Trial https://t.co/KPBoe3cQvq

Apr 22, 2020 · 3 likes · 3 shares · 6,722 followers View post →