@neuromichael Interesting that the pattern of brain activity is inverse, as is the impact on gene expression patterns (well, eudaimonic well being, not exactly purpose, but in part). https://t.co/08NBIA4IXI
Loneliness, eudaimonia, and the human conserved transcriptional response to adversity.
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Nov 2016 – Jul 2024Where it's discussed
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The discussions reflect a general agreement on the link between social factors and health, exemplified by comments about how loneliness affects immune functions and how eudaimonic wellbeing can counteract negative effects. The tone varies from scientific interest to skepticism, but overall, the content underscores the importance of social connection and purpose in maintaining health.
Most discussions align with the article's findings, especially on how social connection and purpose influence health, though some posts debate specific mechanisms like immune function.
The discussions show moderate curiosity about the biological and psychological implications of social adversity, but lack deep exploration.
Posts include references to scientific concepts and personal opinions but overall do not deeply analyze or challenge the article.
The conversations highlight the relevance of social well-being to health, indicating some awareness of potential health implications.
Abstract in brief
- Chronic social adversity activates the conserved transcriptional response to adversity (CTRA), which increases inflammatory gene expression and decreases antiviral/antibody-related gene expression.
- The study found that loneliness is associated with upregulated CTRA, but eudaimonic wellbeing (a sense of purpose and meaning in life) is linked to reduced CTRA activity; in joint analyses, eudaimonic wellbeing more strongly countered loneliness effects.
- Promoting eudaimonic wellbeing may help mitigate health risks linked to social isolation by offsetting the negative impact of loneliness on gene expression related to inflammation and immune response.]
Top posts
Most liked on X and BlueskyPerceived social isolation and degree of perceived purpose and happiness impact health, especially the immune system. Loneliness, Eudaimonia, and the Human Conserved Transcriptional Response to Adversity - PubMed https://t.co/2wIFQL7Ms6
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@neuromichael Interesting that the pattern of brain activity is inverse, as is the impact on gene expression patterns (well, eudaimonic well being, not exactly purpose, but in part). https://t.co/08NBIA4IXI
@JoeTaranto @Jeff_Menaker @andyroddick You can keep throwing insults and I'll keep throwing studied to prove my point. https://t.co/wH5moxvJHx Masks don't work https://t.co/YPVYewkLQn https://t.co/yh9oqYlRlq And lack of social interaction lowers immune functions. The masks are a farce, sorry to be the bearer
Perceived social isolation and degree of perceived purpose and happiness impact health, especially the immune system. Loneliness, Eudaimonia, and the Human Conserved Transcriptional Response to Adversity - PubMed https://t.co/2wIFQL7Ms6
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