Alzheimer Dis Assoc Disord November 2017 PMID 26295747

Antidepressant Use in the Elderly Is Associated With an Increased Risk of Dementia.

Chenkun Wang, Sujuan Gao, Hugh C Hendrie, Joe Kesterson, Noll L Campbell, Anantha Shekhar, Christopher M Callahan

Mentions

20
Peak: 5 in Jan 2021
across 7 sources since Apr 2018

Extended reach

23,003
potential audience

Total likes

11

Video views

572

Mentions per month

Apr 2018 – Sep 2025

Where it's discussed

  • X / Twitter9 posts
  • Facebook3 posts
  • YouTube2 videos
  • News2 articles
  • Blogs2 articles
  • Instagram1 posts
  • LinkedIn1 posts

AI synopsis

What people are saying

The overall discussions reveal a cautious tone, with posts like '@medicalcoverup' expressing concerns about medication practices, and others highlighting the population-level risks, showing active engagement and awareness of the potential consequences of antidepressant use in the elderly. The tone combines concern with critical reflection, emphasizing the importance and possible influence of the findings without outright dismissal or enthusiasm.

AgreementModerate agreement

Most discussions express concern or acknowledgment of the potential link between antidepressant use and dementia, indicating a general agreement or recognition of the findings.

InterestHigh interest

The posts show high interest, with many commenting on implications and raising questions about causality and clinical practice.

EngagementModerate engagement

Participants are engaging by referencing specific concerns, such as undetected delirium and the effects of medication, demonstrating a moderate depth of discussion.

ImpactModerate impact

The conversations highlight a perceived significant impact, especially concerning patient safety and medical practices, but without definitive conclusions, so the impact score remains moderate.

Abstract in brief

  • A retrospective study of 3,688 elderly patients found that those using antidepressants, specifically SSRIs and non-SSRIs, had a higher risk of developing dementia compared to depressed patients not using antidepressants and non-depressed nonusers.
  • The study used Cox proportional hazard models to analyze the data, revealing that SSRI users had an 83% increased risk and non-SSRI users had a 50% increased risk of dementia.
  • Further research is necessary to confirm these findings, understand the mechanisms involved, and determine if the association applies to other populations.]

Top posts

Most liked on X and Bluesky
Medical Cover Up
@medicalcoverup · X

@wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use antipsychotics after calling it dementia." Antidepressant use in the elderly is associated with an increased risk of dementia https://t.co/rbKJQYiAYr

Jan 21, 2021 · 6 likes · 4 shares · 1,299 followers View post →
UltimApe
@ultimape · X

SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase https://t.co/WWwicXWhR7

Jul 16, 2021 · 4 likes · 2 shares · 6,756 followers View post →
recovery&renewal
@recover2renew · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 4,163 followers View post →
Dee
@Deedoherty2 · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 3,995 followers View post →
This Salemite survived Kancamagus
@bledwine · X

RT @ultimape: SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase http…

May 29, 2023 · 2 shares · 3,892 followers View post →
Thomas W.
@ThomasWillNot · X

RT @ultimape: SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase http…

May 29, 2023 · 2 shares · 751 followers View post →

All mentions

This Salemite survived Kancamagus
@bledwine · X

RT @ultimape: SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase http…

May 29, 2023 · 2 shares · 3,892 followers View post →
Thomas W.
@ThomasWillNot · X

RT @ultimape: SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase http…

May 29, 2023 · 2 shares · 751 followers View post →
UltimApe
@ultimape · X

SSRI use might be partly causal factor for alzheimers https://t.co/Z2RZrJeimx With noted population level risk increase https://t.co/WWwicXWhR7

Jul 16, 2021 · 4 likes · 2 shares · 6,756 followers View post →
ハルキ&パートナー
@condensersumida · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 632 followers View post →
Me
@Jstanthrnobdy · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 560 followers View post →
Dee
@Deedoherty2 · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 3,995 followers View post →
recovery&renewal
@recover2renew · X

RT @medicalcoverup: @wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use ant…

Jan 21, 2021 · 4 shares · 4,163 followers View post →
Medical Cover Up
@medicalcoverup · X

@wendyburn @NICEGetInvolved I'm sure you understand my concerns! "We cause undetected delirium, ignore it then use antipsychotics after calling it dementia." Antidepressant use in the elderly is associated with an increased risk of dementia https://t.co/rbKJQYiAYr

Jan 21, 2021 · 6 likes · 4 shares · 1,299 followers View post →
Linda Carney MD
@lindacarneymd · X

https://t.co/3UhVLfUmsu blog: Antidepressant Use in the Elderly Is Associated With an Increased Risk of Dementia in Antidepressants. https://t.co/GAcRrFeyJe https://t.co/wOmhlp2dry

Jun 1, 2020 · 242 followers View post →
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