PubHawk
November 2015 PMID 26323041

Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock.

Andréa M C Ventura, Huei Hsin Shieh, Albert Bousso, Patrícia F Góes, Iracema de Cássia F O Fernandes, Daniela C de Souza, Rodrigo Locatelli Pedro Paulo, Fabiana Chagas, Alfredo E Gilio

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Mentions

49
Peak: 9 in Apr 2019
across 6 sources since Jan 2019

Extended reach

144,654
potential audience

Total likes

1,013

Video views

32,573

Mentions per month

Jan 2019 – Jan 2025

Where it's discussed

  • X / Twitter29 posts
  • Facebook8 posts
  • Blogs5 articles
  • YouTube3 videos
  • News3 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Several discussions highlight the study’s clinical relevance, with phrases like 'this trial favors adrenaline over dopamine,' indicating awareness of its implications for treatment choice. The tone varies from clinical commentary—such as noting 'we almost never use dopamine'—to acknowledgment of the study’s influence, using words like 'favors' and 'supports' to emphasize the study's significance. Overall, the tone suggests a recognition of the research's potential to inform practice, though some remarks are brief and practical rather than deeply analytical.

AgreementModerate agreement

Most discussions express some level of support or validation for the study, with comments indicating that dopamine is rarely used in some units or that the findings support favoring epinephrine in pediatric septic shock.

InterestHigh interest

There is high interest, as posts highlight the significance of the research and relate it directly to clinical practice, especially with phrases like 'favours' and references to changing treatment choices.

EngagementModerate engagement

Posts show moderate engagement, referencing specific details of the trial like its design and implications, though most are brief mentions rather than in-depth analysis.

ImpactModerate impact

While not uniformly pervasive, some comments suggest the study could influence clinical protocols or spark change, indicating a perception of meaningful impact.

Abstract in brief

  • This study is a randomized controlled trial comparing dopamine and epinephrine as first-line treatments for pediatric septic shock, focusing on 28-day mortality.
  • Results showed a higher death rate in the dopamine group compared to the epinephrine group, with dopamine also linked to a greater risk of healthcare-associated infections.
  • The trial was conducted from 2009 to 2013 in Brazil, involving children aged 1 month to 15 years who met criteria for fluid-refractory septic shock, with various outcomes and safety measures analyzed.
Read the full abstract

Top posts

Most liked on X and Bluesky
Goodishintent
@omnintensivist.bsky.social · Bluesky

Dopamine is for Dinosaurs I can't speak for the NICU but we almost never use dopamine in my PICU. pubmed.ncbi.nlm.nih.gov/26323041/

Jan 26, 2025 · 15 likes · 7 shares View post →
Richard Hollander MD || RAHollander.bsky.social
@RA_Hollander · X

@leejanhau @CantillMauricio @sgdambrauskas @diegovinci @PedsICUPoll Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/wKQ45skOG9 This trial also favors adranaline over dopamine for septic shock

Apr 30, 2019 · 6 likes · 3 shares · 306 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Mar 11, 2019 · 1 like · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 3, 2019 · 1 like · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 4, 2019 · 1 like · 1 share · 4,414 followers View post →
Treatment Scores
@TreatmentScores · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Mar 15, 2019 · 1 share · 8,450 followers View post →

All mentions

Goodishintent
@omnintensivist.bsky.social · Bluesky

Dopamine is for Dinosaurs I can't speak for the NICU but we almost never use dopamine in my PICU. pubmed.ncbi.nlm.nih.gov/26323041/

Jan 26, 2025 · 15 likes · 7 shares View post →
أديب بن طاهر خواجي Adeeb Khawaji
@AdeebKhawaji · X

RT @RA_Hollander: @leejanhau @CantillMauricio @sgdambrauskas @diegovinci @PedsICUPoll Double-Blind Prospective Randomized Controlled Trial…

Apr 30, 2019 · 3 shares · 2,069 followers View post →
Álava, César MD
@cesarinalava19 · X

RT @RA_Hollander: @leejanhau @CantillMauricio @sgdambrauskas @diegovinci @PedsICUPoll Double-Blind Prospective Randomized Controlled Trial…

Apr 30, 2019 · 3 shares · 212 followers View post →
Richard Hollander MD || RAHollander.bsky.social
@RA_Hollander · X

@leejanhau @CantillMauricio @sgdambrauskas @diegovinci @PedsICUPoll Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/wKQ45skOG9 This trial also favors adranaline over dopamine for septic shock

Apr 30, 2019 · 6 likes · 3 shares · 306 followers View post →
KGH Library Service
@KGHNHSLibrary · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Apr 23, 2019 · 1 share · 604 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Apr 23, 2019 · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Apr 18, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Apr 12, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Apr 8, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Apr 5, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Mar 18, 2019 · 4,414 followers View post →
Treatment Scores
@TreatmentScores · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Mar 15, 2019 · 1 share · 8,450 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Mar 11, 2019 · 1 like · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Mar 9, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Mar 1, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 19, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 15, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 12, 2019 · 4,414 followers View post →
Dr.houssein jaffal
@jaffal13 · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Feb 9, 2019 · 1 share · 3,128 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 9, 2019 · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 7, 2019 · 4,414 followers View post →
debbie fearon she/her
@debbie_fearon · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Feb 4, 2019 · 1 share · 2,081 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Feb 4, 2019 · 1 like · 1 share · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 23, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 19, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 14, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 10, 2019 · 4,414 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 7, 2019 · 4,414 followers View post →
Dr Khalid
@rauf_khalid · X

RT @tripdatabase: New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Dr…

Jan 3, 2019 · 1 share · 2,486 followers View post →
Trip Database
@tripdatabase · X

New2Trip: Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock https://t.co/PdRCvT30kZ

Jan 3, 2019 · 1 like · 1 share · 4,414 followers View post →