March 2016 PMID 26339067

Coffee and caffeine consumption and depression: A meta-analysis of observational studies.

Longfei Wang, Xiaoli Shen, Yili Wu, Dongfeng Zhang

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Mentions

171

Peak: 24 in Mar 2022

across 7 sources since Jan 2017

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1,297,459

potential audience

Total likes

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Jan 2017 – Aug 2025

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AI synopsis

What people are saying

The discussions highlight various aspects of the research, with users noting that, according to one analysis, each cup of coffee consumed correlates with an 8% reduced risk of depression. Posts such as 'Coffee consumption is linked to lower rates of depression' and 'Inclusive el Consumo de café al día 2-3 tazas, se asocia a menor riesgo para padecer depresión' reflect a tone that conveys optimism and invites further exploration of the findings. This suggests a collective sentiment that values the publication's insights while encouraging further discourse on the topic.

AgreementModerate agreement

The majority of discussions generally support the findings of the article regarding coffee and depression, although some express caution due to the robustness of the studies.

InterestHigh interest

Posts demonstrate a high level of curiosity about the link between caffeine and depression, with many users directly referencing the article and related studies.

EngagementModerate engagement

Some discussions delve deeper into specific findings and methods used in the various studies, indicating a moderate level of engagement.

ImpactHigh impact

Many contributors recognize the potential significance of coffee consumption in mental health, suggesting a strong perceived impact.

Abstract in brief

The meta-analysis reviewed the link between coffee/caffeine intake and depression, incorporating data from 11 observational studies with over 330,000 participants.
Results indicated that higher coffee consumption was associated with a reduced risk of depression, with an 8% decrease in risk for each additional cup consumed daily.
For caffeine, a nonlinear relationship was found, showing reduced depression risk at moderate intake levels (between 68 mg to 509 mg per day), which became significant at higher consumption.

Read the full abstract

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Moritz Negwer

@moritz-negwer.mstdn.science.ap.brid.gy · Bluesky

@Edwin085 The science says: maybe yes, but studies are typically underpowered and therefore not terribly conclusive. See e.g. here: https://pubmed.ncbi.nlm.nih.gov/26339067/ "[...] evidence of a linear association was found between coffee consumption and depression, and the risk of depression […]

Aug 25, 2025 View post →

Cesal

@B0ngb1ngb1ng · X

@anglopjdst https://t.co/SYt58MwhsD https://t.co/S3YoMARqD8 https://t.co/dldcx73zM5 https://t.co/swt0FS6pj8

Mar 28, 2025 · 216 followers View post →

Blowing in the wind

@Blowinginthew10 · X

Coffee and caffeine consumption and depression: A meta-analysis of observational studies - PubMed https://t.co/qcU0jfIYOD

Sep 17, 2024 · 350 followers View post →

BereNice Ⓜ️©

@BereMCoronel · X

RT @carlos_arnaud: @DrMauricioGon Exacto Inclusive el Consumo de café ☕️ al día 2-3 tazas, se asocia a menor riesgo para padecer depresión…

Nov 1, 2023 · 3 shares · 132 followers View post →

Malu Brown

@BrownMalu · X

RT @carlos_arnaud: @DrMauricioGon Exacto Inclusive el Consumo de café ☕️ al día 2-3 tazas, se asocia a menor riesgo para padecer depresión…

Oct 3, 2023 · 3 shares · 363 followers View post →

@CirujanoGZ · X

RT @carlos_arnaud: @DrMauricioGon Exacto Inclusive el Consumo de café ☕️ al día 2-3 tazas, se asocia a menor riesgo para padecer depresión…

Oct 3, 2023 · 3 shares · 28,313 followers View post →

Dr. Carlos Arnaud

@carlos_arnaud · X

@DrMauricioGon Exacto Inclusive el Consumo de café ☕️ al día 2-3 tazas, se asocia a menor riesgo para padecer depresión Saludos Mau https://t.co/aBLmairZN1

Oct 3, 2023 · 17 likes · 3 shares · 21,269 followers View post →

د. بلسم عبدالرحمن

@BashHaz · X

المصدر: Coffee and caffeine consumption and depression: A meta-analysis of observational studies - Longfei Wang, Xiaoli Shen, Yili Wu, Dongfeng Zhang, 2016

Oct 1, 2023 · 818 followers View post →

David Haldorsen MA, ISSA-EPT-SCC-SN

@YourCoachDavid · X

RT @BradStanfieldMD: References https://t.co/EFHFpqaxcU https://t.co/HF7p9mPCqY https://t.co/h8MfTJlwAU https://t.co/bgusumPYuB https://…

Sep 10, 2023 · 1 share · 67,402 followers View post →

Dr Brad Stanfield

@BradStanfieldMD · X

Sep 10, 2023 · 5 likes · 1 share · 29,185 followers View post →

Gerard Meyer

@gerardmeyer · X

@Codie_Sanchez @awilkinson Definitely coffee @awilkinson https://t.co/ZWsI2A1SI4 https://t.co/YqTAM2NYqh

Aug 14, 2023 · 44 followers View post →

Avinash Sunder

@vsavinash · X

@theliverdr @theliverdr there seems to be a small error in the link to one of the papers (https://t.co/g7YRBdeGdn)

Aug 14, 2023 · 40 followers View post →

These Muscles

@these_muscles · X

5. Linked to a lower risk of depression According to one review of seven studies, each cup of coffee people consumed per day was linked to an 8% lower risk of depression. https://t.co/5ky3nf9BxM

Jan 27, 2023 · 9 followers View post →

Dra. Thalya Krügger 

@DraKrugger · X

Jan 13, 2023 · 1 like · 1,540 followers View post →

Jakub Wojtasik 608 271 402 Telefon Zaufania dla ♂

@j_wojtasik · X

Badania: https://t.co/In6nDd7lnA

Sep 29, 2022 · 53 followers View post →

✨Siren✨

@SirensCallCo · X

Huh.. "the risk of depression decreased faster and the association became significant when the caffeine consumption was above 68 mg/day and below 509 mg/day." Source: https://t.co/e4wkn3PDmI https://t.co/fZw2qeuACA

Sep 19, 2022 · 5 likes · 1,049 followers View post →

د. عبدالمجيد الفاخري (دكتور شبكية)

@AlFakhriA · X

https://t.co/7T5WdFZBUo https://t.co/Xqmf3RUR9x https://t.co/NiufbAO7DC

Aug 26, 2022 · 7 likes · 23,869 followers View post →

No war!!! Victory for Ukraine!!!

@Makasyaba · X

RT @dweisa: https://t.co/T9W8BLEyYx

Jun 11, 2022 · 1 share · 840 followers View post →

Alexey Weiss, MD

@dweisa · X

https://t.co/T9W8BLEyYx

Jun 11, 2022 · 13 likes · 1 share · 25,534 followers View post →

Sonia Sinchiguano

@SoniSinchiguano · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

May 12, 2022 · 26 shares · 150 followers View post →

Franchesco ⚒️

@DrFranchescoLee · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

May 5, 2022 · 26 shares · 2,947 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @marciak5410: Coffee and caffeine consumption and depression: A meta-analysis of observational studies - PubMed https://t.co/57gQigogiL

May 4, 2022 · 1 share · 6,710 followers View post →

Marcia Kelligan

@marciak5410 · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

May 4, 2022 · 26 shares · 545 followers View post →

Marcia Kelligan

@marciak5410 · X

Coffee and caffeine consumption and depression: A meta-analysis of observational studies - PubMed https://t.co/57gQigogiL

May 4, 2022 · 1 share · 545 followers View post →

Paul Ibáñez

@hoover0172 · X

Conclusions: Coffee and caffeine consumption were significantly associated with decreased risk of depression. https://t.co/K56SsDCvCH

May 4, 2022 · 91 followers View post →

CLASO

@claso10 · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

May 4, 2022 · 26 shares · 368 followers View post →

Pablo A. Méndez

@PabloAMndez2 · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

May 4, 2022 · 26 shares · 8 followers View post →

Claudio Rubio

@claudiododdoli · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

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Jesvs 0rtega

@byChuy0rtega_ · X

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《Hashira

@WDuranHz · X

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@Luis_TrejoSV · X

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Dan-Thor

@Dan47115732 · X

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Skankin-Hod 69 (JManuelCruzR) 

@jmanuelcruzr · X

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Romano

@RomanoJA · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

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Kara de Miguel Ángel Bounarroti

@kara240303 · X

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mastergonz

@benitogonzalo1 · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

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diego ponce

@diegoarponce · X

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Tonny Dominguez

@TonnyDominguez6 · X

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Ricardo Hernandez 

@sambernardo2 · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

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javier ospina

@javierospina20 · X

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Yuri Beltrán

@yuribeltran · X

RT @DrMauricioGon: https://t.co/ZhgsyhmiNE

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Mauricio Gonzalez MD.

@DrMauricioGon · X

https://t.co/ZhgsyhmiNE

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Stacey Freedenthal

@SFreedenthal · X

@vkivlighan @benzosarebad @jill_d35 @Altostrata @atomicaceso @sarahislam_MD @RichardBentall I wonder if these beneficial effects of tea are based on the caffeine…? It’s associated with lowered depression too. https://t.co/160aicFvaW

Mar 11, 2022 · 4,344 followers View post →

Rich Kingston

@RichKingston73 · X