PubHawk
Int J Obes (Lond) March 2016 PMID 26365102

Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies.

P J Rogers, P S Hogenkamp, C de Graaf, S Higgs, A Lluch, A R Ness, C Penfold, R Perry, P Putz, M R Yeomans, D J Mela

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Mentions

227
Peak: 5 in Oct 2021
across 6 sources since Apr 2019

Extended reach

410,849
potential audience

Total likes

1,634

Video views

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Apr 2019 – Apr 2025

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AI synopsis

What people are saying

Various posts express agreement with the systematic review, noting that human studies show no effect on gut health or insulin sensitivity, with phrases like 'NO effect' signaling strong support. The tone is cautious yet supportive, emphasizing the evidence's implications for health debates without deep technical discussion, showing moderate engagement and recognition of the research's potential importance.

AgreementModerate agreement

Most discussions align with the systematic review's conclusion that low-energy sweeteners do not significantly impact body weight or energy intake.

InterestModerate interest

Participants show mild interest, as they mention specific study results and comparisons without extensive detailed analysis.

EngagementModerate engagement

Comments reference specific aspects like gut microflora, insulin sensitivity, and the evidence from studies, indicating moderate engagement.

ImpactModerate impact

The collective posts reflect a reasonable recognition that the research findings could influence ongoing debates about sweetener safety and efficacy.

Abstract in brief

  • Low-energy sweeteners (LES) are expected to reduce energy intake and body weight by lowering the energy density of foods, but the evidence from various studies is mixed.
  • In animal studies, most showed no effect or decreased body weight with LES, while some suggested increased weight, often comparing LES to glucose; human studies, mostly observational, found inconsistent links between LES use and body mass index.
  • Meta-analyses of short-term and sustained human trials suggest that LES tend to reduce energy intake before meals and are associated with modest reductions in body weight, indicating they are unlikely to increase energy intake or weight gain.
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Top posts

Most liked on X and Bluesky
Layne Norton, PhD
@BioLayne · X

In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTppn https://t.co/kWZbkQjScS https://t.co/zCgCiMiOt7 https://t.co/I4vdeShtpj https://t.co/kg14flppGg https://t.co/yutwuylLfP https://t.co/DtAGGp3RhG GET REKT

Oct 15, 2021 · 44 likes · 4 shares · 226,427 followers View post →
jasper
@swagsper · X

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Apr 8, 2025 · 5 likes · 853 followers View post →
Fat Fighting
@FatFightingClub · X

สารทดแทนความหวานไม่กระตุ้นอินซูลินนะครับ อธิบายกันจนไม่รู้จะอธิบายยังไง เอาเปเปอร์ไปอ่านเถอะ https://t.co/xngtB4Tqok https://t.co/UGpPNpNO5b https://t.co/1A89jM8ZdO https://t.co/NdaQHAtCNn https://t.co/uJTgkdC6nM https://t.co/LRSfC22Kxc https://t.co/It1DV26EGA

Oct 24, 2021 · 3 likes · 9,940 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Oct 26, 2021 · 4 shares · 99,266 followers View post →
Jacob Gudiol
@JacobGudiol · X

@d_tenn81 Det finns några studier på det med. När man summerat dem har en studie kommit fram till att sötningsmedel möjligen är lite bättre än vatten https://t.co/VICs1hoBZN En annan fann ingen skillnad https://t.co/1xvafavpvx https://t.co/xjK32fH2q4

Mar 22, 2023 · 24,434 followers View post →
Jose C Souto, MD
@jcsouto · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Oct 15, 2021 · 4 shares · 14,542 followers View post →

All mentions

jasper
@swagsper · X

https://t.co/VSNAZvryOJ https://t.co/8mBCYqxaUU https://t.co/wXFLS1tyrC https://t.co/pR3sdsdHhY https://t.co/AjFa4znXtI https://t.co/e9J6R3J4Y5 https://t.co/fpREnnAJbQ https://t.co/fZS6elgQeK https://t.co/JMmvoTgAzL

Apr 8, 2025 · 5 likes · 853 followers View post →
HoopsW
@13BoltSD · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Jul 27, 2024 · 4 shares · 298 followers View post →
Jacob Gudiol
@JacobGudiol · X

@d_tenn81 Det finns några studier på det med. När man summerat dem har en studie kommit fram till att sötningsmedel möjligen är lite bättre än vatten https://t.co/VICs1hoBZN En annan fann ingen skillnad https://t.co/1xvafavpvx https://t.co/xjK32fH2q4

Mar 22, 2023 · 24,434 followers View post →
Ragi Mudde
@2emkay · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Oct 26, 2021 · 4 shares · 959 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Oct 26, 2021 · 4 shares · 99,266 followers View post →
Fat Fighting
@FatFightingClub · X

สารทดแทนความหวานไม่กระตุ้นอินซูลินนะครับ อธิบายกันจนไม่รู้จะอธิบายยังไง เอาเปเปอร์ไปอ่านเถอะ https://t.co/xngtB4Tqok https://t.co/UGpPNpNO5b https://t.co/1A89jM8ZdO https://t.co/NdaQHAtCNn https://t.co/uJTgkdC6nM https://t.co/LRSfC22Kxc https://t.co/It1DV26EGA

Oct 24, 2021 · 3 likes · 9,940 followers View post →
Jose C Souto, MD
@jcsouto · X

RT @BioLayne: In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTpp…

Oct 15, 2021 · 4 shares · 14,542 followers View post →
Layne Norton, PhD
@BioLayne · X

In fact, HUMAN studies show NO effect of artificial sweeteners on gut microflora & insulin sensitivity https://t.co/Qk8OkpTppn https://t.co/kWZbkQjScS https://t.co/zCgCiMiOt7 https://t.co/I4vdeShtpj https://t.co/kg14flppGg https://t.co/yutwuylLfP https://t.co/DtAGGp3RhG GET REKT

Oct 15, 2021 · 44 likes · 4 shares · 226,427 followers View post →