Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institutionalized people over 4.5 years. What can we conclude from this? https://t.co/6rdbtza6Hg https://t.co/qyypVJK4fx
Test of effect of lipid lowering by diet on cardiovascular risk. The Minnesota Coronary Survey.
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Jan 2019 – Oct 2025Where it's discussed
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X / Twitter69 posts
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AI synopsis
What people are saying
The discussions encompass a range of views about the Minnesota Coronary Survey, with some users stating that 'the higher their cholesterol, the longer they lived' which suggests a belief in alternative conclusions than what the study presents. Other individuals criticize the interpretations of the data, labeling them as 'distorted' or 'based on lies'. The tone varies from confrontational to analytical, with many references to external studies, suggesting a need to justify or critique established dietary guidelines.
The posts reflect mixed opinions, with some users clearly questioning the study's validity, while others dispute interpretations.
There is a moderate level of curiosity, as many discussions reference the study directly and provide links or summaries.
Some users engage more deeply by referencing other studies or historical context, but many posts reflect superficial arguments.
While some users express strong opinions about the study's implications, overall sentiment indicates uncertainty about its broader significance.
Abstract in brief
- The Minnesota Coronary Survey was a long-term, double-blind clinical trial involving 9,057 institutionalized adults aimed at assessing the impact of a low-fat diet on heart health.
- The study compared a control diet (39% fat, 18% saturated) to a treatment diet (38% fat, 9% saturated) over an average of 384 days and found that while serum cholesterol levels decreased, there were no significant differences in cardiovascular events or mortality between the two diet groups.
- Some positive trends were observed in younger participants, but overall, the study concluded that dietary changes did not significantly affect heart disease risk in the larger population.
Top posts
Most liked on X and BlueskySeed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institutionalized people over 4.5 years. What can we conclude from this? https://t.co/6rdbtz9yRI https://t.co/FZT9dykPlC
@dylanarmbruste3 @Veganella_ Here's an earlier pub https://t.co/q6H0nXn1Vp
@FrogHarmless @mrc314 @Nutradvance The RCT in the Minnesota Coronary Survey took place in strictly controlled environments. Subjects were 9570 residential inpatients, observed for years. Original study, published in 1989 https://t.co/9FxctoZk7r Re-evaluation, published in 2016 https://t.co/9FxctoZk7r https://t.co/jBAMre07LX
Animal Fats have always been healthy, They proved it with a controlled experiment, then waited decades to publish. #Meatheals https://t.co/uWTy9xKrtF
@dbirch214 @DawnTJ90 Real butter. Read about the Minnesota Coronary Experiment https://t.co/8ill8ZRReY https://t.co/8ID2pex8tM https://t.co/T9DLU0ySLe
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@VigilantFox @MidwesternDoc cardiovascular deaths, or total mortality. A favorable trend for all these end-points occurred in some younger age groups." Your presentation is a thorough distortion of the study, from its history to its findings. https://t.co/9AKvkH9VXT
@prime_sapiens Here's a link to the study. See for yourself that it DOES NOT support this claim. https://t.co/n9ZJtjG7yS
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institutionalized people over 4.5 years. What can we conclude from this? https://t.co/6rdbtza6Hg https://t.co/qyypVJK4fx
@meathead @bigfatsurprise https://t.co/s2QdhfqWGH
@dylanarmbruste3 @Veganella_ Here's an earlier pub https://t.co/q6H0nXn1Vp
@CarolinaGoldYum Since you're such an idiot who doesn't do his research, let me help you. https://t.co/z3WwdADTfd https://t.co/tF53sAwajO https://t.co/MixaJ5vWqQ https://t.co/6BhESnWRCD https://t.co/3KVg1nA3cP https://t.co/ZkDn08MlYd
@DudzLightLime @DrGaryMcGowan You're asking about the attrition, but the relevant literature will tell you that this trial was imposed extreme malnutrition. This isn't my opinion. This is the statements from the literature about MCE you seem unfamiliar with. https://t.co/k1coRyyoVm
@SwipeWright https://t.co/B5vd2EyzfB
@jeremykauffman https://t.co/thlxdUlvF1
@WALTamath @bigfatsurprise @terrysimpson @MohammedAlo @DrSiyabMD Still no DOIs ! Nice evasion ! You are still WRONG ! https://t.co/k9HmnMLvhh
https://t.co/2HVS5UVLd9
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
@hufcm @LowCarbVet @dylanarmbruste3 @GardnerPhD @American_Heart AFAIK, there are no high-quality RCTs other than these; each is powered to detect a 20%—30% effect size of SFA→PUFA for primary effect variable: DART 10.1016/S0140-6736(89)90828-3 MCS 10.1161/01.ATV.9.1.129 MRCT 10.1016/S0140-6736(68)90746-0 RCOT 10.1136/bmj.1.5449.1531 SDHS
@dylanarmbruste3 @hufcm @GardnerPhD @American_Heart OK. These are the high-quality RCTs of SFA→PUFA: DART 10.1016/S0140-6736(89)90828-3 MCS 10.1161/01.ATV.9.1.129 MRCT 10.1016/S0140-6736(68)90746-0 RCOT 10.1136/bmj.1.5449.1531 SDHS 10.1007/978-1-4684-0967-3_18 Using Taleb’s method of reverse engineering the probability https://t.co/ZbeKg2bVCx
@hufcm @dylanarmbruste3 @GardnerPhD @American_Heart You cite the debunked Hooper review (Cochrane)? The reliable RCTs of SFA→PUFA: DART 10.1016/S0140-6736(89)90828-3 MCS 10.1161/01.ATV.9.1.129 MRCT 10.1016/S0140-6736(68)90746-0 RCOT 10.1136/bmj.1.5449.1531 SDHS 10.1007/978-1-4684-0967-3_18 My analysis: https://t.co/t4DSG4ZYMB
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
RT @robertlufkinmd: Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institu…
Seed oils lower serum cholesterol but decrease overall survival. In a prospective controlled study of ~10,000 institutionalized people over 4.5 years. What can we conclude from this? https://t.co/6rdbtz9yRI https://t.co/FZT9dykPlC
@whohead1 @approfre @ElieJarrougeMD Again LDL has zero causal RCT evidence of any disease. IT IS THE HIGH DOSE OF CARBOHYDRATES WHICH IS CAUSAL. 1️⃣ https://t.co/ySLQ4teXWm 2️⃣ https://t.co/8JWOrkLH1r 3️⃣ https://t.co/1U71Q8LS5r 4️⃣ https://t.co/oB2oR4MYHq 5️⃣ https://t.co/VHUc8tcDzU 6️⃣ https://t.co/fXpvHyuGjM
@Bennel44 @MichielT40 @r_gamba @netflix This is simply not true, you'd know this if you read the study instead of listening to a video by a known liar. There is 0 mention of soybean oil. https://t.co/LrzNidRVNe https://t.co/FBlrgLMh6Z
Test of effect of lipid lowering by diet on cardiovascular risk. The Minnesota Coronary Survey https://t.co/zZpFObjRH3
RT @Yuri_Bezmen0v: Animal Fats have always been healthy, They proved it with a controlled experiment, then waited decades to publish. #Mea…
RT @Yuri_Bezmen0v: Animal Fats have always been healthy, They proved it with a controlled experiment, then waited decades to publish. #Mea…
Animal Fats have always been healthy, They proved it with a controlled experiment, then waited decades to publish. #Meatheals https://t.co/uWTy9xKrtF
@BioLayne https://t.co/45On3L5mRB https://t.co/mA5E5swrq7 https://t.co/fD823htogo https://t.co/131dc9fi72 https://t.co/tTYHZTeVcl https://t.co/D6Y1KJLWNU (this is cool) https://t.co/tysOF8scC9 https://t.co/dZCbHBklMm (this is the BEST RCT hidden in the meta analysis you provided)
@RlyAverageDave @shelly_187 @Konzepts @RichardWebste16 1️⃣ https://t.co/PMuVF3s2pA 2️⃣ https://t.co/J1wb4NwWEN 3️⃣ https://t.co/ySLQ4teXWm 4️⃣ https://t.co/1U71Q8LS5r 5️⃣ https://t.co/oB2oR4MYHq
@salimishmael_ Debunked: Also fast food contains trans fat because it's cooked in processed "heart healthy" industrial sludge known as seed oils https://t.co/Ya99GfZu0g
@HRashid_ @jakeshieldsajj yes, your cholesterol will be higher. i know how this is going to sound, but that is what you want. this is probably the best-performed dietary study ever. the higher their cholesterol, the longer they lived. https://t.co/IzWUF4r0hK
@AnnChildersMD @Nutradvance The original publication (not until 1989) did not show a lower risk of death. Absolutely did not say "clear benefit." https://t.co/y4XEHrx27h
@FrogHarmless @mrc314 @Nutradvance The RCT in the Minnesota Coronary Survey took place in strictly controlled environments. Subjects were 9570 residential inpatients, observed for years. Original study, published in 1989 https://t.co/9FxctoZk7r Re-evaluation, published in 2016 https://t.co/9FxctoZk7r https://t.co/jBAMre07LX
@FearZero4 @CarnivoreDad @skydog576 @SBakerMD 2 largest-ever NIH-funded, RCTs, concluded that sat fats had no effect on cardiovascular mortality or total mortality. A 2016 analysis shows 22% higher risk for each 30 mg/dL reduction in serum cholesterol. https://t.co/kvrLK71eEe https://t.co/UpEQUhnPX2 https://t.co/ooUoRPm8DX
@hormonedietdoc LOL .. another ASSOCIATIONAL STUDY which BY design CAN NOT PROVE CAUSATION! LDL is NOT a metric of concern! https://t.co/kesVilQzyD ➡️ https://t.co/aa3Amh569y ➡️ https://t.co/oB2oR4MYHq ➡️ https://t.co/PkLMm1YjWW ➡️ https://t.co/Fvu39UuEVf https://t.co/GnT6L92nvN
@mhd25112 @VeganRecovering @WildWarriorNut Good documentary. https://t.co/9mODpLenNv (at 8:20 in video) Dr Ivan Frantz did a study in the 60s on cardiovascular disease called The Minnesota Coronary Survey. Those who ate the diet that lowered lipids and cholesterol ended up dying sooner. https://t.co/ZVOM3Md93h
They said saturated fat would kill you. Said it for decades. Said meat is bad b/c of it. The truth: largest test ever conducted on sat. fat found "no differences between the treatment & control groups for cardiovascular events/deaths or total mortality." https://t.co/kR2yLjvKMd
@JTayScience @REV_Insulin_Res Star Trek logical thinking -10 Argumentum Ad Vercundiam ( Appeal to Authority) https://t.co/9kZTiN2JHC ➡️ https://t.co/Gj5p60eltr ➡️https://t.co/oB2oR4MYHq ➡️ https://t.co/yUCwWzOruY ➡️ https://t.co/zJCNwDFVgb
@PlantsRunning @KenDBerryMD A single case if true means nothing since it states nothing about confounders ! 1️⃣ https://t.co/jHQSZRw43j 2️⃣ https://t.co/3ePbh9nWlX 3️⃣ https://t.co/zTL6p84Em4 4️⃣ https://t.co/Gw4pI71cIg 5️⃣ https://t.co/Gj5p60eltr 6️⃣ https://t.co/oB2oR4MYHq 7️⃣ https://t.co/yUCwWzOruY
https://t.co/rDSpVPh90E
https://t.co/ByuSeyRfpy Minnesota Coronary Survey Ivan D. Frantz Jr., Emily A. Dawson, Patricia L. Ashman, Lael C. Gatewood, Glenn E. Bartsch, Kanta Kuba, and Elizabeth R. Brewer The Minnesota Coronary Survey was a 4.5-year, open enrollment, single end-time, double-blind trial
@Plant_proof @renatodumbra Test of Effect of Lipid Lowering by Diet on Cardiovascular Risk The Minnesota Coronary Survey Jan-Feb 1989;9(1):129-35. doi: https://t.co/oB2oR4MYHq
@SteakAndIron Original: https://t.co/n3L6brslNR Full recovered: https://t.co/LFkoxzbRZw Our video on the whole story: https://t.co/lUzJ2L0DBK
@TylerCartwright @mosca_matthew @BiggestComeback @NutritionMadeS3 No the official dietary guidelines and the background dietary advise has been proven to be wrong and based on lies . Paid the price never again ! I do what I’ve subjected to my own testable hypothesis to see if it valid . https://t.co/oB2oR4MYHq ➡️ https://t.co/yUCwWzOruY
Test of Effect of Lipid Lowering by Diet on Cardiovascular Risk. The Minnesota Coronary Survey https://t.co/h1Yy4WVeva Read carefully. Does nor support lowering fat in diet
@steph93065 @McDonalds Have you heard of the Minnesota Coronary Experiment? Higher cholesterol correlated with **reduced** all-cause mortality at a statistically significant level. https://t.co/8ill8ZRReY https://t.co/8ID2pex8tM
RT @pgeerkens: @dbirch214 @DawnTJ90 Real butter. Read about the Minnesota Coronary Experiment https://t.co/8ill8ZRReY https://t.co/8ID2pex…
@dbirch214 @DawnTJ90 Real butter. Read about the Minnesota Coronary Experiment https://t.co/8ill8ZRReY https://t.co/8ID2pex8tM https://t.co/T9DLU0ySLe
@vegansie 75% of 9000+ dropped out over 4.5 years. That's still a ton of people that completed a fully medically supervised inpatient metabolic ward study. Hardly 'worthless'. Again, the researchers didn't say that. You did. https://t.co/veAVz4Ybye
@leighayn0528 Do you know the Minnesota Coronary Experiment? https://t.co/iaXenqVLI4 and https://t.co/8ill8ZRReY
@Sadrien_GW2 Minnesota: whipped topping as diet intervention? Who cares... "filled milk and ice cream, a whole egg substitute, soft margarine, whipped topping, filled cheese, low fat ground beef with added vegetable oil, and filled sausage products." https://t.co/S3TV2iV7t6
@DiegoNSalman @ShaneOL1976 @KetoAurelius Here is the intervention: "Products that proved particularly useful were filled milk and ice cream, a whole egg substitute, soft margarine, whipped topping, filled cheese, low fat ground beef with added vegetable oil, and filled sausage products" https://t.co/S3TV2iV7t6
@KetoAurelius @PeterAttiaMD Fascinating story. @garytaubes mentioned this trial in GCBC. Study [https://t.co/yQFvYzbdnM] went unpublished for 16 years (Frantz in GCBC: “We were just disappointed in the way it came out.”). Check out @Gladwell on this: https://t.co/X1FvyYTf9p