Ann Intern Med October 2015 PMID 26458258

Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial.

Yftach Gepner, Rachel Golan, Ilana Harman-Boehm, Yaakov Henkin, Dan Schwarzfuchs, Ilan Shelef, Ronen Durst, Julia Kovsan, Arkady Bolotin, Eran Leitersdorf, Shoshana Shpitzen, Shai Balag, Elad Shemesh, Shula Witkow, Osnat Tangi-Rosental

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Mentions

192
Peak: 3 in Feb 2022
across 6 sources since Mar 2021

Extended reach

224,439
potential audience

Total likes

36

Video views

1,779

Mentions per month

Mar 2021 – Aug 2025

Where it's discussed

  • News144 articles
  • Facebook24 posts
  • X / Twitter13 posts
  • Blogs8 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions show a balanced interest, with posts mentioning the study's positive findings about wine and diabetes, such as better lipid control, reflecting curiosity and acknowledgment of potential benefits. The tone varies from cautious skepticism to recognition of possible health implications, influenced by mentioning of scientific studies and personal interpretations.

AgreementModerate agreement

Most discussions acknowledge the study's findings that moderate wine consumption may benefit diabetics' cardiometabolic parameters.

InterestModerate interest

Comments demonstrate moderate interest, referencing specific results like lipid improvements and noting the relevance of genetic factors.

EngagementModerate engagement

Participants engage by discussing study details, such as trial design and outcomes, and by referencing existing research and personal opinions.

ImpactModerate impact

The discussions highlight some influence on perceptions of alcohol's health effects, with mentions of potential clinical relevance and ongoing debates.

Abstract in brief

  • This 2-year randomized controlled trial explored the effects of moderate alcohol intake, specifically red and white wine, on cardiovascular and metabolic health in adults with well-controlled type 2 diabetes, within the context of a Mediterranean diet.
  • The study found that red wine significantly improved HDL cholesterol and apolipoprotein A1 levels, and reduced the total cholesterol to HDL ratio, whereas both wines benefited slow ethanol metabolizers by improving glycemic control markers like fasting glucose and HbA1c, especially in carriers of the ADH1B1 allele.
  • Overall, the findings suggest that moderate red wine consumption may support some cardiovascular benefits in people with type 2 diabetes, but genetic factors influence individual responses, and more long-term studies are needed to clarify its safety and effectiveness.

Top posts

Most liked on X and Bluesky
WesElyMD
@WesElyMD · X

12/ Should diabetics drink alcohol in moderation? A 2-year study of 224 stable Diabetics randomized to 150 ml of water, white wine, or red wine. All on Mediterranean diet. Wine was superior to water in reducing lipids & controlling sugars in diabetics.   https://t.co/afHiMukjTA

Feb 14, 2022 · 13 likes · 3 shares · 57,299 followers View post →
Vicent Tomás, Diabetes conCiencia
@diabconciencia · X

El consumo de 150ml de vino tinto con la cena en pacientes diabéticos tipo 2 mostró una mejora moderada de parámetros cardiometabólicos (2 años de duración, sin diferencias en la función hepática con el grupo control). https://t.co/TooxeVhl1O

Mar 22, 2021 · 5 likes · 4,978 followers View post →
Annals of Int Med
@AnnalsofIM · X

Pairing your Thanksgiving feast with a glass of red wine may be beneficial for patients with #diabetes. Learn more: https://t.co/o6OscJxmIU #HappyThanksgiving https://t.co/ZmefyhvLPf

Nov 24, 2022 · 3 likes · 1 share · 72,613 followers View post →
@docbio.bsky.social
@DocBio1509 · X

@schuellerstats @Hieflo23

Mar 8, 2022 · 3 likes · 462 followers View post →
Español Charlatan
@es_charlatan · X

Para los que piensan que beber diariamente vino con la comida es alcoholismo. https://t.co/lwxJESsCyI

Apr 18, 2024 · 1 like · 1,490 followers View post →
Español Charlatan
@es_charlatan · X

Para los que piensan que vender diariamente vino con la comida es alcoholismo. https://t.co/lwxJEStaog

Apr 18, 2024 · 1 like · 1,490 followers View post →

All mentions

Kardioklick
@kardioklick.bsky.social · Bluesky

Of course you can randomize and it can be done: Tell group A to drink a glass of red wine every day, tell group B to drink a glass of white wine every day. Then count cardiovascular events. There is in fact a trial like this, but no effect on hard endpoints: pubmed.ncbi.nlm.nih.gov/26458258/

Dec 18, 2024 · 1 like · 1 share View post →
Español Charlatan
@es_charlatan · X

Para los que piensan que beber diariamente vino con la comida es alcoholismo. https://t.co/lwxJESsCyI

Apr 18, 2024 · 1 like · 1,490 followers View post →
Español Charlatan
@es_charlatan · X

Para los que piensan que vender diariamente vino con la comida es alcoholismo. https://t.co/lwxJEStaog

Apr 18, 2024 · 1 like · 1,490 followers View post →
Annals of Int Med
@AnnalsofIM · X

Pairing your Thanksgiving feast with a glass of red wine may be beneficial for patients with #diabetes. Learn more: https://t.co/o6OscJxmIU #HappyThanksgiving https://t.co/ZmefyhvLPf

Nov 24, 2022 · 3 likes · 1 share · 72,613 followers View post →
Johan Rudolfsson
@Biltokig2030 · X

@SanderPit95 @TurciosRaphael @stevenmarkryan Wine is actually better than water in moderate consumption: https://t.co/g06CP632Ur

Oct 3, 2022 · 36 followers View post →
@docbio.bsky.social
@DocBio1509 · X

@schuellerstats @Hieflo23

Mar 8, 2022 · 3 likes · 462 followers View post →
John Greaves
@JohnGre73362514 · X

@cjsnowdon I suppose it's therefore fortunate that wine drinking appears to be beneficial for diabetics: https://t.co/aW4JiOQpPt

Feb 16, 2022 · 39 followers View post →
Skatiq
@Skatiq3 · X

RT @WesElyMD: 12/ Should diabetics drink alcohol in moderation? A 2-year study of 224 stable Diabetics randomized to 150 ml of water, whit…

Feb 14, 2022 · 3 shares · 275 followers View post →
WesElyMD
@WesElyMD · X

12/ Should diabetics drink alcohol in moderation? A 2-year study of 224 stable Diabetics randomized to 150 ml of water, white wine, or red wine. All on Mediterranean diet. Wine was superior to water in reducing lipids & controlling sugars in diabetics.   https://t.co/afHiMukjTA

Feb 14, 2022 · 13 likes · 3 shares · 57,299 followers View post →
Health Nerd
@GidMK · X

@cjsnowdon @AndyTowersNZ On top of that, in terms of the very modest RCT literature (i.e. https://t.co/u3BheeGqpP https://t.co/T7P7HeyWp0) There is at best a very small, likely clinically insignificant benefit for moderate increases in alcohol intake on cardiovascular parameters

Nov 16, 2021 · 74,539 followers View post →
Grownmangrumbles
@Grownmangrumble · X

2/ Studies with controls suggest zero short-term benefits to the health from drinking which leaves us concerned only with long term effects. https://t.co/9Lft0bhNiZ

Oct 6, 2021 · 2,325 followers View post →
Luke
@garnetghoornyy · X

https://t.co/okRw4icgCJ https://t.co/wlcLQbfhh7

Jun 8, 2021 · 94 followers View post →
Michael Plishka
@plish · X

Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial: Annals of Internal Medicine: Vol 163, No 8 https://t.co/TdpuhidF4Y

Apr 14, 2021 · 7,005 followers View post →
Vicent Tomás, Diabetes conCiencia
@diabconciencia · X

El consumo de 150ml de vino tinto con la cena en pacientes diabéticos tipo 2 mostró una mejora moderada de parámetros cardiometabólicos (2 años de duración, sin diferencias en la función hepática con el grupo control). https://t.co/TooxeVhl1O

Mar 22, 2021 · 5 likes · 4,978 followers View post →