February 2016 PMID 26499447

Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome.

Robert H Lustig, Kathleen Mulligan, Susan M Noworolski, Viva W Tai, Michael J Wen, Ayca Erkin-Cakmak, Alejandro Gugliucci, Jean-Marc Schwarz

Mentions

295
Peak: 3 in Dec 2020
across 6 sources since Oct 2015

Extended reach

2,712,423
potential audience

Total likes

29,893

Video views

2,602,400

Mentions per month

Oct 2015 – Aug 2025

Where it's discussed

  • News170 articles
  • Facebook66 posts
  • X / Twitter33 posts
  • Blogs17 articles
  • YouTube5 videos
  • Reddit4 posts

AI synopsis

What people are saying

The discussions frequently highlight the quick and significant health improvements observed in children after sugar and fructose restriction, e.g., 'paranemaan 9 päivässä,' showing excitement about the findings. Words like 'reversed,' 'improved,' and questions about weight loss underscore the focus on metabolic health beyond just weight management. The tone varies from supportive and enthusiastic to skeptical, reflecting diverse perspectives on the research's implications.

AgreementStrong agreement

Most discussions strongly support the findings of the publication, emphasizing that reducing fructose and sugar intake can lead to metabolic health improvements regardless of weight loss.

InterestHigh interest

The posts reflect high interest, with many referencing specific details of the study, including its findings on metabolic markers and the rapid improvements observed in children within just 9 days.

EngagementHigh engagement

Numerous participants actively analyze the study's implications, question traditional views, and share personal opinions, showing deep engagement with the research and its significance.

ImpactModerate impact

While there is strong consensus about the importance of dietary changes, some comments focus on broader systemic issues or skeptically address the implementation, indicating perceived high influence but some variation in perceived practical impact.

Abstract in brief

  • This study investigated whether replacing dietary sugar with starch, while keeping total calories the same, could improve metabolic health in Latino and African American children with obesity and metabolic syndrome, showing improvements in blood pressure, lipid levels, and glucose tolerance.
  • The results indicated that reducing dietary fructose led to significant health benefits even without weight loss, suggesting that fructose restriction alone can positively impact metabolic parameters in children with obesity and metabolic syndrome.
  • The findings support the idea that dietary modifications focusing on sugar reduction, rather than calorie reduction, can help improve metabolic health in at-risk children.]

Top posts

Most liked on X and Bluesky
Dave Wu 2.0
@heydavewu · X

A 2015 study discovered that lowering fructose consumption while maintaining the same caloric intake improved children's health with obesity and metabolic syndrome https://t.co/jDpZzwvj1z What about weight loss?...

Jul 3, 2023 · 10 likes · 2,019 followers View post →
Leonie Elizabeth
@leoniee54 · X

@theabroma @erreyedoc @Dave06031956 @NigelKinbrum @superbirdman1 @IronLindaJ @FatEmperor @CakeNutrition @IMWHorvitz @gerdosi @DietScold @JimJohnsonSci @BarryCPearson @ChristianTams @KetoDocCLT @rmuncy81 @Chrest_brett @MikeCarrato @MarikaSboros @ProfTimNoakes @virtahealth @FructoseNo @KenDBerryMD @DoctorTro @lowcarbGP @DrAseemMalhotra @zoeharcombe @SBakerMD Same person. See this: 'study determined whether isocaloric substitution of starch for sugar would improve metabolic parameters" conclusions "Isocaloric fructose restriction improved surrogate metabolic parameters" https://t.co/voj6z5naY9

Feb 4, 2019 · 3 likes · 1 share · 385 followers View post →
Shashi Iyengar | Accredited Metabolic Health Coach
@shashiiyengar · X

@thesneha_ @RobertLustigMD https://t.co/7gXdNbOr8B

Dec 6, 2023 · 2 likes · 28,959 followers View post →
Peter Österberg, Ph.D.
@Genlearnman · X

@JTayScience @ryanattar @helsinkiuni @svenska_yle @CSundstrm He dismissed PURE and Ramsden et al 2016: https://t.co/ziD21X3S4Y and went ballistic over these #NutriRecs papers: Han et al 2019: https://t.co/dS7SJyYpU9 @methodsnerd et al 2019: https://t.co/CZms77ogYS Zeraatkar et al 2019: https://t.co/x7xENsZFdZ

Mar 18, 2024 · 2 likes · 1 share · 1,417 followers View post →
Kille Tölönen
@Neonomide · X

@MattiSuhonen1 @PaiviKorpivaara Kalorien ja suolan kannalta juu. Mut metaboliseen terveyteen liittyy muutakin. Sokerirajoituksella voi olla myös paljon merkitystä: https://t.co/Ki6D0ouMU5 https://t.co/aerC4enHk4

Apr 21, 2024 · 2 likes · 923 followers View post →
Kille Tölönen
@Neonomide · X

@OsmoSoininvaara @sfprkp Voihan karkkien vaihto sipseihin olla hyödyksikin. Tässä lyhyessä tutkimuksessa terveysmarkkerit paranivat lapsilla jo 9 päivässä ilman muutosta painossa. https://t.co/Ki6D0ouMU5 https://t.co/VdEt1BgIhX

Oct 17, 2024 · 2 likes · 1 share · 923 followers View post →

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Vyso
@Vysoforlife · X

@UlTaraMAGA @malhdavis @SecKennedy Part 1 - Evidence https://t.co/NmUgbSCCoa (studies linked) https://t.co/myrzWwgZbG https://t.co/SGDKOoqTFm https://t.co/F0zbu6RfZk https://t.co/yqRxeoT05O https://t.co/RPGqrwsOIP

Aug 28, 2025 · 19 followers View post →
Jimmy Otis #TruthMatters #EndCronyism
@james_j_otis · X

@DanimalJG @RealJakeBroe You have not looked for this evidence. https://t.co/9vVWPIlgkf https://t.co/mp5rVE21LS https://t.co/diwmo2Gqev https://t.co/6YMXCWPxpP https://t.co/yV3ifSTQWA https://t.co/EELJq1oOPB https://t.co/jcKFTJygay https://t.co/1og6qAJ1qe https://t.co/AzC3Dt6Yzy https://t.co/DCbkwcLM3a

Jul 17, 2025 · 722 followers View post →
Vesalius de Mitochondrie
@aoneatwoa123 · X

@DrPlantel @vrabecj https://t.co/TVH1d6SnnN

Dec 1, 2024 · 140 followers View post →
Tuomas Tumi
@TuomasTumi · X

RT @Neonomide: @OsmoSoininvaara @sfprkp Voihan karkkien vaihto sipseihin olla hyödyksikin. Tässä lyhyessä tutkimuksessa terveysmarkkerit pa…

Oct 17, 2024 · 1 share · 962 followers View post →
Kille Tölönen
@Neonomide · X

@OsmoSoininvaara @sfprkp Voihan karkkien vaihto sipseihin olla hyödyksikin. Tässä lyhyessä tutkimuksessa terveysmarkkerit paranivat lapsilla jo 9 päivässä ilman muutosta painossa. https://t.co/Ki6D0ouMU5 https://t.co/VdEt1BgIhX

Oct 17, 2024 · 2 likes · 1 share · 923 followers View post →
Kille Tölönen
@Neonomide · X

@KatjaKurk Tässä tutkimuksessa saatiin lasten sokeri- ja rasva-arvot paranemaan 9 päivässä vaihtamalla karkit sipseihin: https://t.co/Ki6D0ouMU5 https://t.co/nwv6p40q5U

May 24, 2024 · 923 followers View post →
Kille Tölönen
@Neonomide · X

@MattiSuhonen1 @PaiviKorpivaara Kalorien ja suolan kannalta juu. Mut metaboliseen terveyteen liittyy muutakin. Sokerirajoituksella voi olla myös paljon merkitystä: https://t.co/Ki6D0ouMU5 https://t.co/aerC4enHk4

Apr 21, 2024 · 2 likes · 923 followers View post →
Dr. Ryan Attar
@ryanattar · X

RT @Genlearnman: @JTayScience @ryanattar @helsinkiuni @svenska_yle @CSundstrm He dismissed PURE and Ramsden et al 2016: https://t.co/ziD21X…

Mar 18, 2024 · 1 share · 4,626 followers View post →
Peter Österberg, Ph.D.
@Genlearnman · X

@JTayScience @ryanattar @helsinkiuni @svenska_yle @CSundstrm He dismissed PURE and Ramsden et al 2016: https://t.co/ziD21X3S4Y and went ballistic over these #NutriRecs papers: Han et al 2019: https://t.co/dS7SJyYpU9 @methodsnerd et al 2019: https://t.co/CZms77ogYS Zeraatkar et al 2019: https://t.co/x7xENsZFdZ

Mar 18, 2024 · 2 likes · 1 share · 1,417 followers View post →
DesignedByNature
@DesignedNature · X

@BioLayne https://t.co/U538btlRSS

Dec 21, 2023 · 438 followers View post →
Shashi Iyengar | Accredited Metabolic Health Coach
@shashiiyengar · X

@thesneha_ @RobertLustigMD https://t.co/7gXdNbOr8B

Dec 6, 2023 · 2 likes · 28,959 followers View post →
Shashi Iyengar | Accredited Metabolic Health Coach
@shashiiyengar · X

Do you think you can stuff your child with sugar? Is your kid obese? Then read this: "Isocaloric fructose restriction improved surrogate metabolic parameters in children with obesity and metabolic syndrome irrespective of weight change" https://t.co/7gXdNbNTj3 https://t.co/b06OKbpZBz

Dec 6, 2023 · 28,959 followers View post →
Dave Wu 2.0
@heydavewu · X

A 2015 study discovered that lowering fructose consumption while maintaining the same caloric intake improved children's health with obesity and metabolic syndrome https://t.co/jDpZzwvj1z What about weight loss?...

Jul 3, 2023 · 10 likes · 2,019 followers View post →
Greta, Esq.
@GQ802 · X

@facepaint_paula @KenDBerryMD It does tho. This study replaced sugar with starch and metabolic disease reversed. https://t.co/xJU8P99nhb

Feb 24, 2023 · 1,545 followers View post →
Sandra Lovelady
@StopTNWO · X

@DrNadolsky Don’t blame the child or the diet; blame the healthcare system that fails them! @RobertLustigMD et al. 2016 https://t.co/fHuaxq6daZ

Jan 11, 2023 · 2 likes · 51 followers View post →
Sandra Lovelady
@StopTNWO · X

@MattElitt @DrNadolsky What happens when they keep eating the same way and regain all the weight? How about if they end up with malabsorption disorders? They didn’t fail their diets; their doctors failed them! https://t.co/fHuaxq6daZ

Jan 11, 2023 · 51 followers View post →
Bryan C
@ProjectEo · X

@KetoAurelius Wow, this is a hot take. It's wrong though. https://t.co/lJscOP2brH https://t.co/Wi42hE0ySW https://t.co/Sr1LrgR5Hj https://t.co/GE4kIs7t3P

May 25, 2021 · 9 followers View post →
LowCarbCarla
@LowCarbCarla · X

@winfinancial @dutchbuckeye @Nutradvance Not everyone gets fat then IR. TOFI don’t get fat still get diabetes etc. This study shows you can improve IR without less calories or losing weight https://t.co/IAlqtQGWFz

Apr 28, 2021 · 838 followers View post →
Liberty1821
@Liberty1821 · X

Love your children? Don't give them sugar, that prohibition includes fruit juice as well. Here's the medical study abstract https://t.co/xx7ersWUUC and take a look at the infographic: @health @uhn @SickKidsNews https://t.co/h8NYFvxKHz

Jan 30, 2021 · 12 followers View post →
Clayto Diogenes
@ClaytoDiogenes · X

@The_Nutrivore @zacharywenger @RDCMSF @CarnivoreMD @DrMauricioGon @AviBittMD ttps://www.npr.org/sections/goatsandsoda/2019/07/19/743500431/study-sugar-rules-the-world-and-ruins-teeth https://t.co/5aPtbJZUSG https://t.co/BoP5I9D5tk https://t.co/CIq0MOmPs0 https://t.co/kfGv7DidmR https://t.co/HztP3Ny5HL https://t.co/QdgphDHvoq https://t.co/uNeqWd9eBC

Dec 26, 2020 · 43 followers View post →
Pixapins
@Pixapins_Docker · X

RT @Pixapins_Docker: Aquí algunes revisions d'estudis: 1/https://t.co/KmTaD0KtfC 2/https://t.co/ayKufKcBcZ 3/https://t.co/fsiyS1Xq1v 4/http…

Dec 14, 2020 · 1 share · 1,239 followers View post →
Pixapins
@Pixapins_Docker · X

Aquí algunes revisions d'estudis: 1/https://t.co/KmTaD0KtfC 2/https://t.co/ayKufKcBcZ 3/https://t.co/fsiyS1Xq1v 4/https://t.co/nysPysWAMe 5/https://t.co/iAWVlSvytU 6/https://t.co/kquxXYD6LB 7/https://t.co/H3fQU1wA0R 8/https://t.co/EXZDrkM5KD

Dec 14, 2020 · 1 share · 1,239 followers View post →
Dr Pran Yoganathan
@pran_dr · X

@BioLayne I’m sick of you being unable to use Pubmed - so here have a read - hopefully @DoctorTro can educate you on some clinical medicine - Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome Obesity 24 (2), 453-460, 2016

Sep 11, 2020 · 1 like · 11,255 followers View post →
Matthew Dalby
@MatthewJDalby · X

The study is here: https://t.co/p82lLbA99w

Jun 12, 2020 · 1 like · 7,371 followers View post →
Caramel & Parsley
@CaramelParsley · X

#Health : Isocaloric Fructose Restriction and Metabolic Improvement in Children With Obesity and Metabolic Syndrome by @RobertLustig et al (2016) https://t.co/DupqDKvcnr #Sugar #children #obesity #carbohydrates

Jun 11, 2020 · 1 like · 455 followers View post →
Tom Andersen
@twitevit · X

@ScepticalDoctor @waynefearn @LoriShemek @RobertLustigMD https://t.co/M3dNHV9x5I

May 25, 2020 · 1,836 followers View post →
FedupfatguyKtwo
@FedupfatguyK · X

@The_Nutrivore @RobertLustigMD “Isocaloric fructose restriction improved surrogate metabolic parameters in children with obesity and metabolic syndrome irrespective of weight change.” doi: 10.1002/oby.21371

Dec 12, 2019 · 388 followers View post →
Clayto's Corner
@ClaytoDem · X

@josevidal29 @OASISfHEALTH @RobertLustigMD https://t.co/WIoYqFKTc3 https://t.co/CqMQnczDCM https://t.co/jHAOlo3xPJ https://t.co/g3m0iyft0m https://t.co/Y7z1pjn18D https://t.co/1rBVXJyYpV

Oct 5, 2019 · 42 followers View post →
Jeff Winkler
@winkler1 · X

@doctorthomaschr @DocRunner1 @harryclax @CocaCola @HughFW @DrAseemMalhotra @ProfTimNoakes @drandyphung @CassellCath @lowcarbGP @realfoodrocksUK @CocaCola_GB @DietCokeGB @RewardsProject @jamesgoolnik @innocent @DrMichaelMosley Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome: https://t.co/HvEbyYPbLe

Aug 29, 2019 · 1,418 followers View post →
Sugar
@Sugar51976529 · X

@SummerDietitian #chronicillness #NAFLD & #T2DM now occur in children, an age group that had never previously manifested such pathologies Additionally dyslipidemia & hypertension two risk factors for cardiovascular disease are now common in childhood https://t.co/nazvpm6W19

Jul 15, 2019 · 1 like · 573 followers View post →
Graham Phillips: The Pharmacist Who Gave Up Drugs
@grahamsphillips · X

Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome - Lustig - 2016 - Obesity - Wiley Online Library https://t.co/B1YKRYlPgc

May 25, 2019 · 5,656 followers View post →
د.دلال أسامة الكاظمي
@Dalal_Alkazemi · X

RT @leoniee54: @theabroma @erreyedoc @Dave06031956 @NigelKinbrum @superbirdman1 @IronLindaJ @FatEmperor @CakeNutrition @IMWHorvitz @gerdosi…

Feb 6, 2019 · 1 share · 4,574 followers View post →
Leonie Elizabeth
@leoniee54 · X

@theabroma @erreyedoc @Dave06031956 @NigelKinbrum @superbirdman1 @IronLindaJ @FatEmperor @CakeNutrition @IMWHorvitz @gerdosi @DietScold @JimJohnsonSci @BarryCPearson @ChristianTams @KetoDocCLT @rmuncy81 @Chrest_brett @MikeCarrato @MarikaSboros @ProfTimNoakes @virtahealth @FructoseNo @KenDBerryMD @DoctorTro @lowcarbGP @DrAseemMalhotra @zoeharcombe @SBakerMD Same person. See this: 'study determined whether isocaloric substitution of starch for sugar would improve metabolic parameters" conclusions "Isocaloric fructose restriction improved surrogate metabolic parameters" https://t.co/voj6z5naY9

Feb 4, 2019 · 3 likes · 1 share · 385 followers View post →