Eur J Pain July 2016 PMID 26517407

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.

D C Hammell, L P Zhang, F Ma, S M Abshire, S L McIlwrath, A L Stinchcomb, K N Westlund

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Mentions

215
Peak: 5 in Mar 2019
across 5 sources since Apr 2017

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294,988
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Total likes

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AI synopsis

What people are saying

Discussions around the article reveal a generally positive perception of the potential medical benefits of transdermal CBD, with comments like 'CBD reduces inflammation very well' and references to personal experiences such as applying CBD to relieve pain. The tone often combines scientific acknowledgment with enthusiasm for practical applications, reflecting both interest and optimism about the research's implications.

AgreementStrong agreement

Most discussions strongly support the findings of the publication, emphasizing that transdermal CBD shows promising anti-inflammatory and analgesic effects, as seen in multiple mentions of the study’s positive results and references to other supporting re

InterestHigh interest

Participants display high curiosity about the research and its applications, frequently mentioning topical CBD, potential health benefits, and advanced research efforts, indicating a strong level of engagement with the topic.

EngagementModerate engagement

Several posts include references to the study’s methodology and real-world implications, such as applying CBD for pain relief, but overall the tone remains somewhat superficial without deep scientific debate, leading to a moderate engagement score.

ImpactModerate impact

While many discussions underscore the potential therapeutic impact of CBD, especially in pain and inflammation reduction, the perception of this study's influence remains cautious, with some posts sharing anecdotal evidence rather than predicting broad cl

Abstract in brief

  • The study investigated the use of transdermal CBD gel to treat arthritis in rats, finding that it significantly reduced inflammation, joint swelling, pain, and immune cell infiltration in a dose-dependent manner without causing noticeable side effects.
  • Results showed that CBD doses of 62 and 62 mg/day were most effective, with plasma CBD levels increasing linearly with dose, and the treatment also lowered proinflammatory biomarkers in the nervous system.
  • Importantly, the treatment did not affect exploratory behavior, suggesting it provides pain and inflammation relief without impairing higher brain functions.]

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Medical Xpress
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Building a better painkiller @harvardmed @elife https://t.co/tMO64vpW58 https://t.co/lBSdlmSjZF

Jul 15, 2022 · 11 likes · 3 shares · 173,117 followers View post →
YallaCBD
@YallaCBD · X

A client just reported that he twisted his ankle, aggravating an old injury; applied 1000mg #CBD topical and in 5 minutes- the pain is gone! I am a #CBDBeliever , R U? pain/inflammation reduction in rats https://t.co/7532b9dzib @healercom_ #cbdcures #cbdlife #Iamnotarat #nopharm

Mar 25, 2019 · 4 likes · 1 share · 20 followers View post →
TheFarmacyUs
@FarmacyUs · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis [full-text pdf]:

Dec 24, 2020 · 2 likes · 1 share · 146 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/041Rt8z58O

Jun 24, 2019 · 1 like · 9,579 followers View post →
@nicolette ☮️
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@robinsoped101 https://t.co/9YDV78p1HJ

Dec 5, 2024 · 1 like · 3,921 followers View post →
michael lenas
@hydromagik · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis ⁦@joerogan⁩ ⁦@bengreenfield⁩ https://t.co/Yj7hZHIcOm

Feb 1, 2019 · 1 like · 540 followers View post →

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@nicolette ☮️
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@robinsoped101 https://t.co/9YDV78p1HJ

Dec 5, 2024 · 1 like · 3,921 followers View post →
Jeffrey Peng, MD
@JeffreyPengMD · X

Animal studies https://t.co/qt4gejaRUI indicate that topical CBD application has therapeutic potential for relief of arthritis pain related behaviors without side effects. Human studies have found similar results.

Dec 15, 2023 · 1,535 followers View post →
The Cannabis Company
@cannacoaus · X

8. A study in the European Journal of Pain shows that topical CBD application may help reduce inflammation and pain related to arthritis. Learn more: https://t.co/wKp0oaYNk5

May 9, 2023 · 1,433 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
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RT @medical_xpress: Building a better painkiller @harvardmed @elife https://t.co/tMO64vpW58 https://t.co/lBSdlmSjZF

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RT @medical_xpress: Building a better painkiller @harvardmed @elife https://t.co/tMO64vpW58 https://t.co/lBSdlmSjZF

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Medical Xpress
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RT @medical_xpress: Building a better painkiller @harvardmed @elife https://t.co/tMO64vpW58 https://t.co/lBSdlmSjZF

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Medical Xpress
@medical_xpress · X

Building a better painkiller @harvardmed @elife https://t.co/tMO64vpW58 https://t.co/lBSdlmSjZF

Jul 15, 2022 · 11 likes · 3 shares · 173,117 followers View post →
Matt Elrod
@melrod42 · X

@CoDoc442 @Peter_Grinspoon You did assert that there is no evidence for CBD helping with pain, when in reality there's plenty. That's not to say CBD never has adverse side-effects, but so what? https://t.co/fhHuT5WS0f

Dec 7, 2021 · 654 followers View post →
GuerillaHealer
@guerillahealer · X

In 2016, researchers showed that a transdermal form of CBD was found to reduce inflammation and pain in rats with arthritis. Higher doses of CBD were linked with greater reductions of pro-inflammatory compounds. https://t.co/zpfjSAwnwZ https://t.co/79k8MduCb1

May 24, 2021 · 115 followers View post →
民族植物学者いさみまし
@isamimasi · X

Transdermal cannabidiolは、関節炎のラットモデルにおける炎症と痛み関連の挙動を減少させる。 https://t.co/gamOKYioNj https://t.co/FxWnmfjbxk #ヘンプ論文

Jan 13, 2021 · 1,087 followers View post →
民族植物学者いさみまし
@isamimasi · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. https://t.co/FxWnmfjbxk #CBD #hemp #cannabidiol

Jan 13, 2021 · 1,087 followers View post →
MRX
@researchmrx · X

RT @FarmacyUs: Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis [full-text pdf]:

Dec 24, 2020 · 1 share · 7,749 followers View post →
TheFarmacyUs
@FarmacyUs · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis [full-text pdf]:

Dec 24, 2020 · 2 likes · 1 share · 146 followers View post →
R B
@baldyboy78 · X

@fourfivecbd hi does this study back up your claims about cdb joint balm? Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis

Sep 27, 2020 · 335 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/WC77rVWmN1

Jul 1, 2019 · 9,579 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/mI5p9maZWb

Jun 27, 2019 · 9,579 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/041Rt8z58O

Jun 24, 2019 · 1 like · 9,579 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/yebhZpnQm2

Jun 21, 2019 · 9,579 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/ZdGWlgL3ZD

Jun 18, 2019 · 9,579 followers View post →
Novus Cannabis HealthPlan
@MMJHealthcare · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis #cannabidiol https://t.co/Np7H0EXa3X #cannabis .@colortheory https://t.co/nhoPtcZZsD

Jun 17, 2019 · 9,579 followers View post →
Dreamgbutterfly
@dreamgbutterfly · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis https://t.co/xS96bw5IHU

May 13, 2019 · 84 followers View post →
snake
@snakefollower · X

RT @drugmonkeyblog: Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. - PubMed - NCBI h…

Mar 28, 2019 · 1 share · 1,216 followers View post →
Drug Monkey
@drugmonkeyblog · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. - PubMed - NCBI https://t.co/cKS9kJr8lw

Mar 28, 2019 · 1 share · 8,774 followers View post →
Chuck Dinsfriend
@cdinsfriend · X

RT @CbdGilead: A client just reported that he twisted his ankle, aggravating an old injury; applied 1000mg #CBD topical and in 5 minutes- t…

Mar 25, 2019 · 1 share · 191 followers View post →
YallaCBD
@YallaCBD · X

A client just reported that he twisted his ankle, aggravating an old injury; applied 1000mg #CBD topical and in 5 minutes- the pain is gone! I am a #CBDBeliever , R U? pain/inflammation reduction in rats https://t.co/7532b9dzib @healercom_ #cbdcures #cbdlife #Iamnotarat #nopharm

Mar 25, 2019 · 4 likes · 1 share · 20 followers View post →
Canna CBD
@canna_cbd · X

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Mar 24, 2019 · 1 like · 56 followers View post →
HuxHemp CBD Apothecary
@HuxHemp · X

@HopkinsMedicine CBD reduces inflammation very well https://t.co/X0dDlZoktO

Feb 26, 2019 · 199 followers View post →
michael lenas
@hydromagik · X

Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis ⁦@joerogan⁩ ⁦@bengreenfield⁩ https://t.co/Yj7hZHIcOm

Feb 1, 2019 · 1 like · 540 followers View post →
Stavros Robis
@stavrosrobis · X

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Jan 15, 2019 · 11 followers View post →