January 2016 PMID 26598726

From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes.

Thibaut Brunet, Detlev Arendt

Mentions

30
Peak: 13 in Jun 2021
across 3 sources since Feb 2019

Extended reach

381,361
potential audience

Total likes

7,000

Video views

220,886

Mentions per month

Feb 2019 – Aug 2023

Where it's discussed

  • X / Twitter25 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions show enthusiasm for the topic, exemplified by comments like 'I liked this video a lot' and references to a documentary series on brain evolution, which reflect excitement and curiosity. Derivative mentions such as 'the origins of the action potential' and discussions about competition among ciliates highlight their engagement with the scientific content, with some referencing specific mechanisms like calcium influx and contraction, demonstrating moderate to deep interest.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some explicitly supporting the evolutionary hypothesis presented.

InterestHigh interest

Participants demonstrate high interest, often highlighting curiosity about the origins of neural functions and evolutionary processes.

EngagementModerate engagement

Comments include references to related videos and detailed queries, indicating moderate to deep engagement with the topic.

ImpactModerate impact

The discussions reflect a recognition that understanding early neural evolution could influence broader fields like neuroscience and microbiology, though this recognition is somewhat implied rather than explicitly stated.

Abstract in brief

  • The text presents an evolutionary hypothesis suggesting that the depolarization-contraction-secretion (DCS) coupling mechanism in animal neuromuscular systems originated in unicellular stem eukaryotes as a response to calcium influx caused by membrane damage.
  • It explains that this initial emergency response was later adapted into an ancient mechanosensory-effector pathway in the last common ancestor of eukaryotes, facilitating movement and cellular responses.
  • Additionally, it discusses how the development of voltage-sensitive sodium-calcium channels in cilia allowed for rapid, coordinated action potentials that spread throughout the cell, leading to specialized cells like neurons and muscle cells, foundational to the nervous system.]

Top posts

Most liked on X and Bluesky
Julio Martinez
@JulioMTNeuro · X

I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has been ‘borrowed’ from mechanosensory contractile cells. https://t.co/eLYvz9Smv7

Mar 29, 2022 · 22 likes · 5 shares · 2,811 followers View post →
Journey to the Microcosmos
@JourneyToMicro · X

In order to avoid being eaten by predators, certain ciliates have evolved the ability to flinch to get out of the way. And when they contract, they can travel as fast as 1,200 body lengths per second! https://t.co/dBz5HYkZhy

Jun 7, 2021 · 20 likes · 4 shares · 7,975 followers View post →
Miles Wischnewski - Psyched!
@MilesWischnews1 · X

Check out our new YouTube mini-series! A documentary about how the brain evolved. Today, the first episode: The first brains. #brain #neuroscience #evolution #Documentary If you like this episode, feel free to share! https://t.co/9CUlgFbkKz

Apr 24, 2021 · 9 likes · 1 share · 1,249 followers View post →
Sveta Molchanova
@Svetadotfi · X

From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes https://t.co/FizWRHn9gt

Feb 18, 2019 · 6 likes · 1 share · 206 followers View post →
Sarah Reiff
@sbreiff · X

@RomainBrette @matthewcobb @WiringTheBrain On a related note, I found this paper by @thibaut_brunet particularly interesting, though the focus isn't primarily ciliates: https://t.co/2NSR4k2r0n

Nov 7, 2022 · 2 likes · 1 share · 333 followers View post →
smekkens
@pandemic_de · X

https://t.co/WpVYxf4mvQ

Jun 26, 2021 · 1 like · 1 share · 1,143 followers View post →

All mentions

Benny Malone
@bennymaloneUK · X

https://t.co/B5PzI1cMLg

Aug 10, 2023 · 4,360 followers View post →
Kevin Mitchell
@WiringTheBrain · X

RT @sbreiff: @RomainBrette @matthewcobb @WiringTheBrain On a related note, I found this paper by @thibaut_brunet particularly interesting,…

Nov 8, 2022 · 1 share · 40,418 followers View post →
Sarah Reiff
@sbreiff · X

@RomainBrette @matthewcobb @WiringTheBrain On a related note, I found this paper by @thibaut_brunet particularly interesting, though the focus isn't primarily ciliates: https://t.co/2NSR4k2r0n

Nov 7, 2022 · 2 likes · 1 share · 333 followers View post →
DirtyBirdGrey
@grey_dirty · X

Evolution Of The Brain: The First Brains | Mini-Series Documentary - Epi... https://t.co/zT3817fRsc via @YouTube

May 13, 2022 · 11 followers View post →
Jibran Khokhar
@DrJKhokhar · X

RT @JulioMTNeuro: I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has…

Apr 2, 2022 · 5 shares · 10,861 followers View post →
kwitschas
@kwitschas · X

RT @JulioMTNeuro: I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has…

Mar 30, 2022 · 5 shares · 1,795 followers View post →
Kathy DelGiorno
@DelgiornoKathy · X

RT @JulioMTNeuro: I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has…

Mar 29, 2022 · 5 shares · 1,913 followers View post →
Hao Yin
@HaoYin20 · X

RT @JulioMTNeuro: I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has…

Mar 29, 2022 · 5 shares · 12,488 followers View post →
Julio Martinez
@JulioMTNeuro · X

I wanted to dig into the origins of the action potential. Well, you may know it isn’t a nervous system invention. It has been ‘borrowed’ from mechanosensory contractile cells. https://t.co/eLYvz9Smv7

Mar 29, 2022 · 22 likes · 5 shares · 2,811 followers View post →
Monika (J) @GreenSkyOverMe@ohai.social
@GreenSky_Jail · X

RT @pandemic_de: https://t.co/WpVYxf4mvQ

Nov 25, 2021 · 1 share · 95 followers View post →
smekkens
@pandemic_de · X

https://t.co/WpVYxf4mvQ

Jun 26, 2021 · 1 like · 1 share · 1,143 followers View post →
Brain Evolution News
@BrainEvolutionN · X

RT @MilesWischnews1: Check out our new YouTube mini-series! A documentary about how the brain evolved. Today, the first episode: The first…

Jun 16, 2021 · 1 share · 1,653 followers View post →
Aspiring friend to local crows
@LarkBrains · X

@UntoNuggan https://t.co/ZzgMNAtTDQ I liked this video a lot

Jun 14, 2021 · 1 like · 247 followers View post →
Thomas R. Stevenson
@ThomasStevenson · X

Flinching Saves Lives in the Microcosmos https://t.co/MxJYInFfbN via @YouTube

Jun 10, 2021 · 2,158 followers View post →
David
@Poetries_bound · X

https://t.co/qSsfgAA8np #microbiology #science #education

Jun 10, 2021 · 873 followers View post →
Sébastien Carassou
@FlashCordon · X

RT @JourneyToMicro: In order to avoid being eaten by predators, certain ciliates have evolved the ability to flinch to get out of the way.…

Jun 8, 2021 · 4 shares · 20,608 followers View post →
Damn Interesting
@DamnInteresting · X

Video: Flinching Saves Lives in the Microcosmos [11:02] https://t.co/TzcCttgz29 https://t.co/UUmIo3SD7r

Jun 7, 2021 · 8,156 followers View post →
Jack
@LecJackS · X

RT @JourneyToMicro: In order to avoid being eaten by predators, certain ciliates have evolved the ability to flinch to get out of the way.…

Jun 7, 2021 · 4 shares · 109 followers View post →
Ruis
@iuRleumas · X

https://t.co/9lOnlaisJ0

Jun 7, 2021 · 152 followers View post →
mel "stillman" vyn
@melvyn_ppn · X

RT @JourneyToMicro: In order to avoid being eaten by predators, certain ciliates have evolved the ability to flinch to get out of the way.…

Jun 7, 2021 · 4 shares · 58 followers View post →
ปังกร
@gggorn · X

Flinching Saves Lives in the Microcosmos https://t.co/LQirPsXO1Z via @YouTube

Jun 7, 2021 · 288 followers View post →
Journey to the Microcosmos
@JourneyToMicro · X

In order to avoid being eaten by predators, certain ciliates have evolved the ability to flinch to get out of the way. And when they contract, they can travel as fast as 1,200 body lengths per second! https://t.co/dBz5HYkZhy

Jun 7, 2021 · 20 likes · 4 shares · 7,975 followers View post →
Miles Wischnewski - Psyched!
@MilesWischnews1 · X

Check out our new YouTube mini-series! A documentary about how the brain evolved. Today, the first episode: The first brains. #brain #neuroscience #evolution #Documentary If you like this episode, feel free to share! https://t.co/9CUlgFbkKz

Apr 24, 2021 · 9 likes · 1 share · 1,249 followers View post →
Kevin Mitchell
@WiringTheBrain · X

RT @Svetadotfi: From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes https://t.c…

Feb 18, 2019 · 1 share · 40,418 followers View post →
Sveta Molchanova
@Svetadotfi · X

From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes https://t.co/FizWRHn9gt

Feb 18, 2019 · 6 likes · 1 share · 206 followers View post →