Nat Biotechnol March 2016 PMID 26878319

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity.

Hyun-Wook Kang, Sang Jin Lee, In Kap Ko, Carlos Kengla, James J Yoo, Anthony Atala

Mentions

237
Peak: 2 in Sep 2024
across 7 sources since Feb 2016

Extended reach

24,856
potential audience

Total likes

312

Video views

17,750

Mentions per month

Feb 2016 – Jun 2025

Where it's discussed

  • News154 articles
  • Facebook46 posts
  • Blogs26 articles
  • X / Twitter5 posts
  • Reddit3 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions highlight the innovative nature of the bioprinting system, with phrases like 'huge step forward' and mentions of creating 'human-scale tissue constructs,' reflecting excitement and acknowledgment of its potential impact. Words like 'breakthrough' and references to clinical relevance emphasize the importance perceived, while questions about future applications show active engagement.

AgreementModerate agreement

Most discussions recognize the significance and potential of the bioprinting technology mentioned in the publication, with some expressing awe at its capabilities.

InterestModerate interest

Posts show curiosity about the progress and potential applications, indicating moderate interest, especially in future medical uses.

EngagementModerate engagement

Participants reference specific aspects like microchannels, tissue types, and future development goals, suggesting active engagement.

ImpactHigh impact

The tone indicates that many believe this system could considerably advance regenerative medicine and tissue engineering, making the publication highly impactful.

Abstract in brief

  • The ITOP is a 3D bioprinting system designed to create large, anatomically accurate tissue constructs with built-in microchannels for nutrient diffusion, addressing the challenge of producing stable, vascularized tissues of clinically relevant size.
  • It achieves structural stability by printing cell-laden hydrogels combined with biodegradable polymers and anchored on sacrificial hydrogels, allowing the formation of complex shapes based on medical imaging data.
  • The system has successfully printed various tissues like bone, cartilage, and muscle, with future goals to develop more complex tissues and organs suitable for human medical applications.]

Top posts

Most liked on X and Bluesky
Piyush
@drpiyushkr · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Jun 3, 2025 · 283 shares · 2,798 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Sep 26, 2024 · 283 shares · 2,570 followers View post →
EWH UCD
@EwhUcd · X

Sources: Kang, H.-W., Lee, S.J., Ko, I.K., Kengla, C., Yoo, J.J. and Atala, A. (2016). A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Nature Biotechnology, [online] 34(3), pp.312–319. Available at: https://t.co/t8o9ypkj7u 4/5

Feb 26, 2021 · 30 followers View post →
gcellcultivo3D
@gcellcultivo3d · X

Did you know that it is now possible to bioprintinh tissue-constructs on a human scale? Reference: https://t.co/BsA0AYQubY Follow us on social media to stay on top of the top news about 3D culture #3d #science #tissueengineering #innovation #bone #regeneration https://t.co/3TWINMpR0M

Dec 17, 2021 · 10 followers View post →
Saurabh Chakrabarty
@Cha45564Saurabh · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Sep 17, 2024 · 283 shares · 1 followers View post →
LRIG.org
@lrig.org · Bluesky

A 3D #bioprinting system to produce human-scale tissue constructs with structural integrity

Feb 22, 2016 View post →

All mentions

Piyush
@drpiyushkr · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Jun 3, 2025 · 283 shares · 2,798 followers View post →
Dr. Rajesh Kumar Meena
@rajeshmeena38 · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Sep 26, 2024 · 283 shares · 2,570 followers View post →
Saurabh Chakrabarty
@Cha45564Saurabh · X

RT @NatureBiotech: A #3D #bioprinting system to produce human-scale tissue constructs with structural integrity https://t.co/IFy8Au7adN htt…

Sep 17, 2024 · 283 shares · 1 followers View post →
gcellcultivo3D
@gcellcultivo3d · X

Did you know that it is now possible to bioprintinh tissue-constructs on a human scale? Reference: https://t.co/BsA0AYQubY Follow us on social media to stay on top of the top news about 3D culture #3d #science #tissueengineering #innovation #bone #regeneration https://t.co/3TWINMpR0M

Dec 17, 2021 · 10 followers View post →
EWH UCD
@EwhUcd · X

Sources: Kang, H.-W., Lee, S.J., Ko, I.K., Kengla, C., Yoo, J.J. and Atala, A. (2016). A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Nature Biotechnology, [online] 34(3), pp.312–319. Available at: https://t.co/t8o9ypkj7u 4/5

Feb 26, 2021 · 30 followers View post →
LRIG.org
@lrig.org · Bluesky

A 3D #bioprinting system to produce human-scale tissue constructs with structural integrity

Feb 22, 2016 View post →