Apple-Derived Pectin Modulates Gut Microbiota, Improves Gut Barrier Function, and Attenuates Metabolic Endotoxemia in Rats with Diet-Induced Obesity.

Abstract in brief

• The study found that apple-derived pectin helps reduce weight gain, improve gut microbiota balance, enhance gut barrier function, and decrease inflammation and metabolic endotoxemia in rats with diet-induced obesity.
• Rats on a high-fat diet showed negative changes in gut bacteria and increased inflammation, but supplementing with pectin restored gut bacteria to normal levels and improved gut barrier markers.
• These findings suggest that consuming apple-derived pectin could be a beneficial strategy for managing obesity-related problems by promoting gut health and reducing systemic inflammation.]