Stem Cell Reports April 2016 PMID 26947977

Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass.

Ge Guo, Ferdinand von Meyenn, Fatima Santos, Yaoyao Chen, Wolf Reik, Paul Bertone, Austin Smith, Jennifer Nichols

Mentions

44
Peak: 7 in Jul 2023
across 5 sources since Mar 2016

Extended reach

169,858
potential audience

Total likes

17

Video views

791

Mentions per month

Mar 2016 – Jul 2023

Where it's discussed

  • News17 articles
  • Blogs11 articles
  • X / Twitter7 posts
  • Facebook6 posts
  • YouTube3 videos

AI synopsis

What people are saying

Several discussions highlight the publication as an important milestone by referring to it as a 'top pick' and emphasizing its role in advancing understanding of naive pluripotent stem cells, using professional tone and focusing on its significance rather than contesting or critiquing the findings.

AgreementModerate agreement

Most discussions recognize the significance of the research, indicating general agreement on its positive contribution to stem cell biology.

InterestModerate interest

Posts show moderate interest, mentioning the study as a notable breakthrough but without enthusiastic enthusiasm.

EngagementModerate engagement

Comments reflect some engagement, such as referencing the publication as a top pick and noting its potential, but lack detailed critique or in-depth analysis.

ImpactModerate impact

The discussion suggests that the research is considered impactful within the field, with mentions of its importance over the past decade and its influence on future research.

Abstract in brief

  • The study shows that under specific kinase inhibition conditions, cells from the human inner cell mass can be directly converted into naive pluripotent stem cells that grow in colonies while maintaining genetic stability and naive cell features.
  • These naive cells exhibit characteristics such as specific marker expression, mitochondrial activity, global gene expression patterns, and low DNA methylation, which are distinct from the more developmentally advanced primed pluripotent cells.
  • The research suggests that these human naive stem cells can differentiate into somatic lineages, indicating a conserved process of pluripotency progression similar to what is observed in mouse embryonic stem cells.]

Top posts

Most liked on X and Bluesky
Cell Press
@CellPressNews · X

Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated cells of the human inner cell mass @ISSCR @martinperaJAX @SCICambridge https://t.co/c9cAKR1QZF https://t.co/r1bkVSqFfw

Jul 6, 2023 · 17 likes · 7 shares · 161,213 followers View post →
Stem Cells Australia
@StemCellsAus · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 4,551 followers View post →
Martin Pera
@martinperaJAX · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 2,381 followers View post →
Ferda
@WinderFerda · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 344 followers View post →
FIROZ MOLLA
@Phi_rose_94 · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 201 followers View post →
Pranav Adithya
@PranavAdithya10 · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 8, 2023 · 7 shares · 195 followers View post →

All mentions

Alejandro De Los Angeles, DPhil, MPH
@delosangeles520 · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 9, 2023 · 7 shares · 86 followers View post →
Pranav Adithya
@PranavAdithya10 · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 8, 2023 · 7 shares · 195 followers View post →
Ferda
@WinderFerda · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 344 followers View post →
FIROZ MOLLA
@Phi_rose_94 · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 201 followers View post →
Stem Cells Australia
@StemCellsAus · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 4,551 followers View post →
Martin Pera
@martinperaJAX · X

RT @CellPressNews: Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated…

Jul 6, 2023 · 7 shares · 2,381 followers View post →
Cell Press
@CellPressNews · X

Editor’s top pick from the last decade of @stemcellreports: Naive pluripotent stem cells derived directly from isolated cells of the human inner cell mass @ISSCR @martinperaJAX @SCICambridge https://t.co/c9cAKR1QZF https://t.co/r1bkVSqFfw

Jul 6, 2023 · 17 likes · 7 shares · 161,213 followers View post →