October 2016 PMID 26965225

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question.

Eugene V Koonin, Petro Starokadomskyy

Mentions

39
Peak: 7 in Mar 2020
across 5 sources since Jan 2020

Extended reach

1,227,908
potential audience

Total likes

29,455

Video views

1,089,248

Mentions per month

Jan 2020 – Nov 2025

Where it's discussed

  • X / Twitter24 posts
  • News11 articles
  • YouTube2 videos
  • Bluesky1 posts
  • Instagram1 posts

AI synopsis

What people are saying

The overall discussion reflects strong agreement with the article, as many posts highlight the continuum of replicator strategies—from selfish to cooperative—using words like 'decisive' and 'misguided' to underscore paradigm shifts. The tone is analytical and thoughtful, emphasizing the importance of redefining how viruses are conceptualized in biology.

AgreementModerate agreement

Most discussions align with the article's view that the old debate about whether viruses are alive is misguided, emphasizing the replicator paradigm as a clearer framework.

InterestHigh interest

Participants show high interest, with references to the paradigm, biological spectrum, and philosophical implications, indicating engagement with deep scientific questions.

EngagementHigh engagement

Many posts discuss concepts like selfish versus cooperative replicators, and cite specific examples like lytic and temperate viruses, demonstrating active and in-depth engagement.

ImpactModerate impact

The discussions seem to influence current understanding by challenging traditional notions and emphasizing a paradigm shift, thus having a moderate to high impact on the scientific discourse.

Abstract in brief

  • The debate over whether viruses are alive is considered misguided because it depends on arbitrary definitions of life, while the replicator paradigm offers a clearer way to understand their role in biology.
  • Within this framework, viruses are seen as selfish replicators, with some, like lytic viruses, being highly selfish, while others, such as temperate viruses, are closer to cooperative forms, illustrating a spectrum of replication strategies.
  • The evolution of life is driven by parasite-host interactions, where selfishness and cooperation among replicators, including viruses and other mobile elements, have shaped biological complexity through coevolution and ongoing adaptive "arms races."

Top posts

Most liked on X and Bluesky
Dr. BioBlogo
@DrBioblogo · X

32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question doi: 10.1016/j.shpsc.2016.02.016 https://t.co/lG7Lpb4M5s

Mar 9, 2020 · 79 likes · 8 shares · 67,232 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/4EKktl9ygL very interesting and readable paper

Dec 6, 2020 · 14 likes · 3 shares · 39,332 followers View post →
(((Dan Graur))) ダン דן גראור
@DanGraur · X

The world of viroids. The old misguided question "Are Viruses Alive" needs to be decisively and permanently buried and forgotten. https://t.co/1YzZpun29G https://t.co/1qnSNDl1Vg

Mar 6, 2025 · 1 like · 1 share · 3,355 followers View post →
Gar✌
@9uillermo_A · X

@MrsDespechos Are viruses alive? The replicator paradigm sheds decisive light on an ... https://t.co/U4bzTRTEE0

Jan 22, 2020 · 1 like · 1,630 followers View post →
Óscar{T} sci-phi
@Oscar_Teix · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 10, 2020 · 8 shares · 8,426 followers View post →
Nigel Ten Fleming
@TenFleming · X

Authority opinion. “The question whether or not "viruses are alive" has caused considerable debate over many years.” (Eugene V Koonin). https://t.co/rMEos1SSfn

Sep 16, 2023 · 2,228 followers View post →

All mentions

Bart Klink
@KlinkBart · X

RT @DanGraur: The world of viroids. The old misguided question "Are Viruses Alive" needs to be decisively and permanently buried and forgot…

Mar 9, 2025 · 1 share · 958 followers View post →
(((Dan Graur))) ダン דן גראור
@DanGraur · X

The world of viroids. The old misguided question "Are Viruses Alive" needs to be decisively and permanently buried and forgotten. https://t.co/1YzZpun29G https://t.co/1qnSNDl1Vg

Mar 6, 2025 · 1 like · 1 share · 3,355 followers View post →
Zorro guardapavos
@drxaverius.bsky.social · Bluesky

koonin al final lo llamaba misguided como pregunta, pero el approach que hay aquí es más cercano al mío que el systems biology del anti del otro paper y creo que es fácil ir de aceptar este paradigma a considerarlso vivos pubmed.ncbi.nlm.nih.gov/26965225/

Mar 3, 2025 · 1 share View post →
Contingently i-RON-ick
@ironick · X

@jensensuther @sckimbriel @deontologistics @lastpositivist example: 'Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question' https://t.co/qSgkbL9fsL And at least one philosopher (Carol Cleland) has written a book on https://t.co/V2uguHHd0B

Apr 18, 2024 · 1,578 followers View post →
Nigel Ten Fleming
@TenFleming · X

Diverse continuum. “Selfish replicators not only belong to the biological realm but are intrinsic to any evolving system of replicators.” (Eugene V Koonin). https://t.co/rMEos1SSfn

Sep 17, 2023 · 2,228 followers View post →
Nigel Ten Fleming
@TenFleming · X

Diverse continuum. “Within this range, typical, lytic viruses represent the selfish extreme whereas temperate viruses and various mobile elements occupy positions closer to the middle of the range.” (Eugene V Koonin). https://t.co/rMEos1Tq4V

Sep 17, 2023 · 2,228 followers View post →
Nigel Ten Fleming
@TenFleming · X

Diverse continuum. “All biological replicators form a continuum along the selfishness-cooperativity axis, from the completely selfish to fully cooperative forms.” (Eugene V Koonin). https://t.co/rMEos1SSfn

Sep 17, 2023 · 2,228 followers View post →
Nigel Ten Fleming
@TenFleming · X

Authority opinion. “Yet, the question is effectively without substance because the answer depends entirely on the definition of life or the state of "being alive" that is bound to be arbitrary.” (Eugene V Koonin). https://t.co/rMEos1SSfn

Sep 16, 2023 · 2,228 followers View post →
Nigel Ten Fleming
@TenFleming · X

Authority opinion. “The question whether or not "viruses are alive" has caused considerable debate over many years.” (Eugene V Koonin). https://t.co/rMEos1SSfn

Sep 16, 2023 · 2,228 followers View post →
susan b costa
@susanbcosta · X

Are viruses alive? The replicator paradigm sheds decisive light on an ... https://t.co/MccfvHuq8W

Jun 21, 2021 · 351 followers View post →
Maulana Empitu
@maempitu · X

RT @DNA_RNA_Uni: Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/4EKktl9ygL…

Dec 7, 2020 · 3 shares · 20 followers View post →
Dataco
@Dataco79 · X

RT @DNA_RNA_Uni: Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/4EKktl9ygL…

Dec 6, 2020 · 3 shares · 206 followers View post →
Cathy
@IndubitablyAcky · X

RT @DNA_RNA_Uni: Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/4EKktl9ygL…

Dec 6, 2020 · 3 shares · 188 followers View post →
DNA&RNA Universe
@DNA_RNA_Uni · X

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/4EKktl9ygL very interesting and readable paper

Dec 6, 2020 · 14 likes · 3 shares · 39,332 followers View post →
markangelodelacruz27
@markangelo_dc27 · X

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question https://t.co/HRzg9uX5zF

Jun 21, 2020 · 261 followers View post →
✨
@lai_dama · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Jun 20, 2020 · 8 shares · 754 followers View post →
aanwangi
@aanwangi · X

Are viruses alive? The replicator paradigm sheds decisive light on an ... https://t.co/fqegszCCml

Mar 15, 2020 · 285 followers View post →
Óscar{T} sci-phi
@Oscar_Teix · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 10, 2020 · 8 shares · 8,426 followers View post →
Mrcel
@madreosa · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 10, 2020 · 8 shares · 113 followers View post →
Carlos Mosqueda
@carlosmen945 · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 9, 2020 · 8 shares · 455 followers View post →
Guzmán
@inyguzman · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 9, 2020 · 8 shares · 362 followers View post →
cindiantonellam
@cindiantonellam · X

RT @DrBioblogo: 32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light…

Mar 9, 2020 · 8 shares · 123 followers View post →
Dr. BioBlogo
@DrBioblogo · X

32) Referencias: Al borde entre lo vivo y lo inerte: 2016. Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question doi: 10.1016/j.shpsc.2016.02.016 https://t.co/lG7Lpb4M5s

Mar 9, 2020 · 79 likes · 8 shares · 67,232 followers View post →
Gar✌
@9uillermo_A · X

@MrsDespechos Are viruses alive? The replicator paradigm sheds decisive light on an ... https://t.co/U4bzTRTEE0

Jan 22, 2020 · 1 like · 1,630 followers View post →
Gar✌
@9uillermo_A · X

Son seres vivos los virus? #Science Are viruses alive? The replicator paradigm sheds decisive light on an ... https://t.co/U4bzTRTEE0. #ParaProfundizarEnNuestraIgnorancia.

Jan 22, 2020 · 1,630 followers View post →
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doi:10.1016/j.shpsc.2016.02.016. PMID 26965225. 44. "virus, n." OED Online. Oxford University Press, March 2015. Web.

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pends on the definition of life or of the “state of being alive”. http://dx.doi.org/10.1016/j.shpsc.2016.02.016 1369-8486/Ó 2016 Published by Elsevier Ltd ...

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in the History and Philosophy of Biology and Biomedical Science. 59: 125–134. doi:10.1016/j.shpsc.2016.02.016. PMC 5406846. PMID 26965225. Rybicki, EP ( ...

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https://doi.org/10.1016/j.shpsc land, MA. .2016.02.016. 63. Li W-H. 1997. Molecular evolution. Sinauer Associates, Sunderland, MA. 39. López-García P. 2012 ...

Dec 12, 2025 View →
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