March 2016 PMID 26978738

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder.

R J T Mocking, I Harmsen, J Assies, M W J Koeter, H G Ruhé, A H Schene

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Mentions

94
Peak: 2 in Nov 2020
across 6 sources since Nov 2020

Extended reach

62,282
potential audience

Total likes

933

Video views

18,819

Mentions per month

Nov 2020 – Jul 2025

Where it's discussed

  • News57 articles
  • Facebook18 posts
  • X / Twitter8 posts
  • Blogs6 articles
  • Reddit3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects cautious optimism, with posts supporting the findings, such as noting omega-3's potential for mood regulation, while some mention the importance of dosage and patient-specific factors. Words like 'may be good' and 'effective' demonstrate tentative agreement, shaping an impression of relevance but not definitive impact.

AgreementStrong agreement

Most posts express support or positive views toward the findings of the meta-analysis, highlighting potential benefits for depression.

InterestModerate interest

Posts show moderate curiosity, with some references to promising effects of omega-3 supplementation and its potential role in mood improvement.

EngagementModerate engagement

Users engage by sharing related studies, emphasizing the significance of the research, and discussing potential applications, indicating active but surface-level involvement.

ImpactModerate impact

The discussions suggest the publication could influence future treatments and interest in omega-3 research, though the overall response remains cautious and exploratory.

Abstract in brief

  • The meta-analysis reviews 13 randomized controlled trials with 1233 adult participants to evaluate the effects of omega-3 polyunsaturated fatty acids (PUFAs), mainly focusing on their potential to improve depressive symptoms in Major Depressive Disorder (MDD).
  • The results indicate that omega-3 PUFAs have a beneficial effect on MDD symptoms, especially with higher doses of eicosapentaenoic acid (EPA), when combined with antidepressant medication, and in studies published earlier.
  • The study emphasizes the need for future personalized treatment trials to determine how factors like EPA dose, medication use, and study characteristics influence the effectiveness of omega-3 supplements in treating depression.]

Top posts

Most liked on X and Bluesky
Roberta Anding
@RobertaAnding · X

Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Feb 24, 2025 · 3 likes · 2 shares · 5,981 followers View post →
Prof Graeme L. Close
@close_nutrition · X

RT @RobertaAnding: Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Feb 24, 2025 · 2 shares · 23,389 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @DrLoBisco: Fish oil may be good for mood: Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for m…

Nov 20, 2020 · 1 share · 6,700 followers View post →
MoyraCosNutrition
@MoyraCosgrove · X

Meta-analysis and meta-regression of #omega3 polyunsaturated fatty acid supplementation for major depressive disorder - PubMed https://t.co/k8DkMzn0um

Mar 7, 2025 · 2,462 followers View post →
MoyraCosNutrition
@MoyraCosgrove · X

RT @RobertaAnding: Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Jul 31, 2025 · 2 shares · 2,462 followers View post →
The Cannabis Company
@cannacoaus · X

4/

May 3, 2023 · 1,431 followers View post →

All mentions

MoyraCosNutrition
@MoyraCosgrove · X

RT @RobertaAnding: Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Jul 31, 2025 · 2 shares · 2,462 followers View post →
MoyraCosNutrition
@MoyraCosgrove · X

Meta-analysis and meta-regression of #omega3 polyunsaturated fatty acid supplementation for major depressive disorder - PubMed https://t.co/k8DkMzn0um

Mar 7, 2025 · 2,462 followers View post →
Prof Graeme L. Close
@close_nutrition · X

RT @RobertaAnding: Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Feb 24, 2025 · 2 shares · 23,389 followers View post →
Roberta Anding
@RobertaAnding · X

Meta-analysis on omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/2KJ1J9CRTE

Feb 24, 2025 · 3 likes · 2 shares · 5,981 followers View post →
The Cannabis Company
@cannacoaus · X

4/

May 3, 2023 · 1,431 followers View post →
Cristian Estrella
@imestrellakris · X

Este otro paper encontró que la suplementación con ácidos grasos omega-3 puede ser efectiva en el tratamiento de la depresión, especialmente en personas con niveles bajos de omega-3 en sangre. https://t.co/RMCljAnQ0z

Mar 28, 2023 · 54 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @DrLoBisco: Fish oil may be good for mood: Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for m…

Nov 20, 2020 · 1 share · 6,700 followers View post →
Dr. LoBisco
@DrLoBisco · X

Fish oil may be good for mood: Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder https://t.co/LDwPWu89TW

Nov 20, 2020 · 1 share · 969 followers View post →