Genome Med May 2016 PMID 27159972

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials.

Nadja B Kristensen, Thomas Bryrup, Kristine H Allin, Trine Nielsen, Tue H Hansen, Oluf Pedersen

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Mentions

40
Peak: 3 in May 2023
across 6 sources since May 2016

Extended reach

629,584
potential audience

Total likes

4,934

Video views

534,731

Mentions per month

May 2016 – Oct 2026

Where it's discussed

  • X / Twitter16 posts
  • YouTube9 videos
  • News5 articles
  • Blogs4 articles
  • Instagram3 posts
  • Reddit3 posts

AI synopsis

What people are saying

The collection mostly fragments the article into quick takes or promotional snippets, with some posts quoting the null findings and others pushing product-specific hype. Word choice leans toward definitive statements in promotional posts (e.g., ‘huge,’ ‘amazing’ results) while academic fragments quote no-effects, creating a mixed, non-cohesive conversation. Overall, the discussion resembles tentative acknowledgment of limited effects, interspersed with marketing noise and generalized recommendations.

AgreementNeither agree nor disagree

The posts collectively show mixed signals: some acknowledge the null or limited effects (neutral stance), while others imply strong claims about probiotic benefits or no benefits. Overall, no clear stance emerges beyond fragmented reactions.

InterestNeutral interest

Moderate interest overall, with several posts promoting probiotic products or videos, suggesting curiosity or engagement, but many posts are promotional or casual, not deeply analytical.

EngagementNeutral engagement

Low to moderate engagement. Many posts are hypey or promotional, not sustained critical discussion; a few share concise quotes from the article, but rigorous debate is rare.

ImpactNeutral impact

Low to moderate perceived impact. The core finding of no significant effect in healthy adults is echoed in some posts, yet promotional content and sensational claims may dilute perceived importance.

Abstract in brief

  • This systematic review analyzed seven randomized controlled trials to determine if probiotic supplements change the fecal microbiota in healthy adults; overall, no significant effects on diversity, richness, or composition were found compared to placebo.
  • Despite various high-throughput molecular methods used, the included studies with medium to high quality did not show consistent evidence that probiotics alter the overall structure of gut bacteria in healthy individuals.
  • The review highlights that, based on current research, probiotic supplementation may not have a measurable impact on fecal microbiota composition in healthy adults, although one study did find some structural changes, indicating more research may be needed.

Top posts

Most liked on X and Bluesky
Raphael Sirtoli
@raphaels7 · X

#probiotics systematic review https://t.co/dbVABrjRf0 "In terms of richness, evenness, or α-diversity measures, no effects were observed on the fecal microbiota composition in any of the included studies when compared to placebo [...]"

Sep 15, 2021 · 7 likes · 3 shares · 8,597 followers View post →
ナカセ|ダイエットコーチ|YouTube37万人
@nakase_22_mr · X

今回の動画は、 ヨーグルトと○○の組み合わせがとんでもなかった! https://t.co/jFjdUMexSo @YouTubeより https://t.co/JCJUQEK8QZ

May 19, 2023 · 5 likes · 1,807 followers View post →
ラッキー
@ay9lz · X

整腸剤と○○の組み合わせがとんでもなかった!ごっそり痩せて腸内環境改善【ビオフェルミン|ビオスリー|ミヤリサン|効果|ビフィズス菌】 https://t.co/Q20XFuo08s @YouTubeより

Jan 24, 2025 · 4 likes · 2,663 followers View post →
L. Amber O'Hearn
@KetoCarnivore · X

@jeronymod @MactatorMaximus @AlexAndreasen2 @shunyata2000 @thinkin_gas @drnickgreiner @mrssjbuchanan @jordanbpeterson See also: https://t.co/8ndAlyJFq6

Apr 30, 2019 · 1 like · 59,924 followers View post →
Daisy_
@djanetz · X

@anaffontelles Quando puderes, leia este artigo:https://t.co/OMko8gqkLe.

Feb 7, 2020 · 1 like · 2,476 followers View post →
ニュース報道伝言板
@dai1kibou · X

ヨーグルトと○○の組み合わせがとんでもなかった!【乳製品|効果|レシピ|メーカー|牛乳|発酵食品|朝|モーニング|ルーティン】 https://t.co/hwC4f0JGC5 @YouTubeより

May 19, 2023 · 9,037 followers View post →

All mentions

Kashiwagi| 研究紹介
@kinniku0P · X

健康な時はプロバイオティクスではなく、プレバイオティクスで腸内フローラを豊かにするという科学的なアプローチ。知っておくと便利だと思います。 ?参考論文:[Systematic review on probiotics in healthy adults](https://t.co/pBg1AC1NZD)

Oct 1, 2026 · 3,447 followers View post →
ラッキー
@ay9lz · X

整腸剤と○○の組み合わせがとんでもなかった!ごっそり痩せて腸内環境改善【ビオフェルミン|ビオスリー|ミヤリサン|効果|ビフィズス菌】 https://t.co/Q20XFuo08s @YouTubeより

Jan 24, 2025 · 4 likes · 2,663 followers View post →
勝@多発性硬化症(2013/1~)
@popeye_4869 · X

整腸剤のあれやこれや 良い動画です https://t.co/UaYiyB1mLs

Sep 21, 2024 · 394 followers View post →
ナカセ|ダイエットコーチ|YouTube37万人
@nakase_22_mr · X

今回の動画は、 【腸活】1番いい整腸剤はどれか? https://t.co/4MV3Cr1oNI https://t.co/4i5pGQYarp

Sep 10, 2024 · 1,702 followers View post →
ゆりー
@bombom202207 · X

https://t.co/O1Zr4cI6Y4

Nov 21, 2023 · 2,426 followers View post →
井之頭五郎指揮官
@inogashiraGoro0 · X

ヨーグルトと○○の組み合わせがとんでもなかった!ヨーグルトの食べ方2選 https://t.co/bGoGUUDF42 @oishinbo_ch オリゴ糖は意識的に接種するか

Jul 7, 2023 · 678 followers View post →
乱世 ケシンロウ求めてる
@reo45197262 · X

ヨーグルトと○○の組み合わせがとんでもなかった!【乳製品|効果|レシピ|メーカー|牛乳|発酵食品|朝|モーニング|ルーティン】 https://t.co/W7ObVxTcbe @YouTubeより

Jun 5, 2023 · 104 followers View post →
ニュース報道伝言板
@dai1kibou · X

ヨーグルトと○○の組み合わせがとんでもなかった!【乳製品|効果|レシピ|メーカー|牛乳|発酵食品|朝|モーニング|ルーティン】 https://t.co/hwC4f0JGC5 @YouTubeより

May 19, 2023 · 9,037 followers View post →
ナカセ|ダイエットコーチ|YouTube37万人
@nakase_22_mr · X

今回の動画は、 ヨーグルトと○○の組み合わせがとんでもなかった! https://t.co/jFjdUMexSo @YouTubeより https://t.co/JCJUQEK8QZ

May 19, 2023 · 5 likes · 1,807 followers View post →
Dev
@Dev70318434 · X

RT @raphaels7: #probiotics systematic review https://t.co/dbVABrjRf0 "In terms of richness, evenness, or α-diversity measures, no effects…

Nov 21, 2021 · 3 shares · 40 followers View post →
Ted Clark
@tedrsa · X

RT @raphaels7: #probiotics systematic review https://t.co/dbVABrjRf0 "In terms of richness, evenness, or α-diversity measures, no effects…

Sep 16, 2021 · 3 shares · 181 followers View post →
Raphael Sirtoli
@raphaels7 · X

#probiotics systematic review https://t.co/dbVABrjRf0 "In terms of richness, evenness, or α-diversity measures, no effects were observed on the fecal microbiota composition in any of the included studies when compared to placebo [...]"

Sep 15, 2021 · 7 likes · 3 shares · 8,597 followers View post →
Daisy_
@djanetz · X

@anaffontelles Quando puderes, leia este artigo:https://t.co/OMko8gqkLe.

Feb 7, 2020 · 1 like · 2,476 followers View post →
Flor Romanial
@romanial_flor · X

RT @ligero999: @jujoalmu @martinfd78 @DocFico @verona5ber @elblogdepills @jvicenteprieto @AngelesRzvz @ElenaSaiz63 @farmagemma @microBIOblo…

Nov 30, 2019 · 9 shares · 1,172 followers View post →
ASAGAYA
@SAKURA79767971 · X

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials https://t.co/NWWLngLz4o #genomemedicine

Jul 2, 2019 · 21 followers View post →
L. Amber O'Hearn
@KetoCarnivore · X

@jeronymod @MactatorMaximus @AlexAndreasen2 @shunyata2000 @thinkin_gas @drnickgreiner @mrssjbuchanan @jordanbpeterson See also: https://t.co/8ndAlyJFq6

Apr 30, 2019 · 1 like · 59,924 followers View post →
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