PubHawk
February 2017 PMID 27261203

Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo.

Y Shao, T He, G J Fisher, J J Voorhees, T Quan

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Mentions

33
Peak: 2 in Dec 2024
across 5 sources since Oct 2021

Extended reach

516,953
potential audience

Total likes

9,882

Video views

508,710

Mentions per month

Oct 2021 – Dec 2024

Where it's discussed

  • News24 articles
  • X / Twitter3 posts
  • Blogs3 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The collective discussions highlight doubts about the claims made by the research, with remarks questioning the validity of small-scale studies and emphasizing the limited real-world impact, as demonstrated by phrases like 'faux intuition' and references to minimal skin improvements. The tone is skeptical and dismissive, which affects the perceived overall importance and engagement with the findings.

AgreementLow agreement

Most posts express skepticism about the significance of the research, referencing anecdotal studies and criticizing the methodology.

InterestNeutral interest

Discussions show minimal curiosity, with some dismissing the topic as minor or exaggerated, indicating low engagement.

EngagementLow engagement

Comments are generally superficial or dismissive, lacking deep analysis or detailed discussion of mechanisms.

ImpactNeutral impact

The overall tone suggests the article is viewed as having limited practical influence or transformative potential.

Abstract in brief

  • Topical retinol (ROL) significantly improves aged human skin by increasing the thickness of the epidermis through stimulating keratinocyte growth and enhancing the activity of key transcription factors.
  • It also boosts the health of the dermis by promoting the proliferation of dermal endothelial cells and fibroblasts, leading to increased production of vital extracellular matrix components like collagen, fibronectin, and elastin.
  • These effects are mediated through activating the TGF-β/CTGF pathway, resulting in better skin structure and function similar to retinoic acid, but without noticeable side effects.
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Top posts

Most liked on X and Bluesky
Gilak!
@fall_north_ · X

@koku_Sabzi https://t.co/PuqU9JAxwW رتینول که توی روتین خودم هست و سرچ کردم. احتمالا مقاله هتی کامل تری هم باشه ... .

Oct 23, 2021 · 1 like · 7,963 followers View post →
美容論文チャンネル
@ragstoriches365 · X

@grass215234 https://t.co/2NXLv2MtWm Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo Y Shao et al. Int J Cosmet Sci. 2017 Feb. https://t.co/ZwtGd0dwqv

Dec 14, 2023 · 1 like · 267 followers View post →
Leo
@leoscosmeticos · X

Esse foram os artigos usados para esse post: Informações e imagem: Shao, Y et al. “Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo.” International journal of cosmetic science vol. 39,1 (2017): 56-65. doi:10.1111/ics.12348

Dec 8, 2024 · 12 followers View post →
Alexandra Delbot
@alexandradelbot.bsky.social · Bluesky

Honnêtement pour la vitamine A c’est pareil, fausse intuition aussi, et de très petites études pour montrer une amélioration de 7% de la peau des fesses pour un suivi de 2 jours et demi (j’exagère à peine, c’est ce que montre cette étude) pubmed.ncbi.nlm.nih.gov/27261203/

Dec 22, 2024 · 1 share View post →

All mentions

Alexandra Delbot
@alexandradelbot.bsky.social · Bluesky

Honnêtement pour la vitamine A c’est pareil, fausse intuition aussi, et de très petites études pour montrer une amélioration de 7% de la peau des fesses pour un suivi de 2 jours et demi (j’exagère à peine, c’est ce que montre cette étude) pubmed.ncbi.nlm.nih.gov/27261203/

Dec 22, 2024 · 1 share View post →
Leo
@leoscosmeticos · X

Esse foram os artigos usados para esse post: Informações e imagem: Shao, Y et al. “Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo.” International journal of cosmetic science vol. 39,1 (2017): 56-65. doi:10.1111/ics.12348

Dec 8, 2024 · 12 followers View post →
美容論文チャンネル
@ragstoriches365 · X

@grass215234 https://t.co/2NXLv2MtWm Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo Y Shao et al. Int J Cosmet Sci. 2017 Feb. https://t.co/ZwtGd0dwqv

Dec 14, 2023 · 1 like · 267 followers View post →
Gilak!
@fall_north_ · X

@koku_Sabzi https://t.co/PuqU9JAxwW رتینول که توی روتین خودم هست و سرچ کردم. احتمالا مقاله هتی کامل تری هم باشه ... .

Oct 23, 2021 · 1 like · 7,963 followers View post →