September 2016 PMID 27324808

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease.

Josep M Argilés, Nefertiti Campos, José M Lopez-Pedrosa, Ricardo Rueda, Leocadio Rodriguez-Mañas

Mentions

87
Peak: 18 in Mar 2020
across 4 sources since Mar 2020

Extended reach

129,432
potential audience

Total likes

160

Video views

8,990

Mentions per month

Mar 2020 – Sep 2025

Where it's discussed

  • X / Twitter54 posts
  • Facebook27 posts
  • YouTube3 videos
  • News3 articles

AI synopsis

What people are saying

Overall, discussions show a balanced recognition of the article's importance, with participants referencing its role in diseases, immune support, and metabolic regulation using words like 'supports,' 'critical,' and 'role,' which convey moderate agreement and engagement. For example, posts highlight muscle as a 'critical physiological reserve' and discuss its involvement in immune and endocrine functions, reflecting a shared understanding of its health impact.

AgreementModerate agreement

Most discussions acknowledge the significance of skeletal muscle in regulating metabolism and its relevance to health, showing general agreement on the article's conclusions.

InterestModerate interest

The posts reflect a moderate level of interest by highlighting key points like muscle's role as a physiological reserve and its impact on immune and metabolic functions.

EngagementModerate engagement

Several posts reference the study directly, emphasizing its importance and implications, which indicates a fair level of detailed engagement.

ImpactModerate impact

Participants emphasize the relevance of muscle in disease contexts and health outcomes, suggesting they see its significant influence.

Abstract in brief

  • Skeletal muscle plays a crucial role beyond movement by regulating energy and protein metabolism throughout the body, acting as a store for glucose and amino acids, which are released during times of increased demand or illness.
  • Muscle loss due to diseases or aging, such as sarcopenia and cachexia, leads to decreased muscle protein and energy, resulting in negative health outcomes like delayed recovery, reduced metabolic rate, disability, and increased healthcare costs.
  • Interventions such as exercise, high-protein diets, and supplements like leucine or HMB can help maintain or restore muscle mass and function, thereby improving health, physical performance, and reversing some of the adverse effects caused by muscle loss.]

Top posts

Most liked on X and Bluesky
es-mig
@esumi_uoeh · X

これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 65 likes · 21 shares · 2,898 followers View post →
Strength For Life
@Strength4_Life · X

Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function! ‘Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease’

Mar 14, 2020 · 30 likes · 21 shares · 11,548 followers View post →
Chris Hattersley
@hattersley4 · X

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https://t.co/h9oLZZ9CcF

Oct 27, 2020 · 29 likes · 6 shares · 1,958 followers View post →
Strength For Life
@Strength4_Life · X

@saeboukglyn @logan_angie @LaterLifeTrain @thecsp @JonRyanCSP @PalingClaire @Claire_Minshull 1. https://t.co/DppjcsHdWS 2. https://t.co/Fl9yr6fqBK 3. https://t.co/vScyNetMke. https://t.co/0wbC8lA7TT

Dec 13, 2022 · 11 likes · 2 shares · 11,548 followers View post →
Strength For Life
@Strength4_Life · X

2a. Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/U7q1w1z9AF https://t.co/nL9Ob9Ocz3

May 15, 2022 · 8 likes · 1 share · 11,548 followers View post →
Strength For Life
@Strength4_Life · X

RT @Strength4_Life: @saeboukglyn @logan_angie @LaterLifeTrain @thecsp @JonRyanCSP @PalingClaire @Claire_Minshull 1. https://t.co/DppjcsHdWS…

Dec 13, 2022 · 2 shares · 11,548 followers View post →

All mentions

Muscle Mass: Critical for Health and Longevity

Muscle is not just aesthetics; it is a strong indicator of health and longevity. More muscle correlates with reduced cardiovascular risk, better sugar and cholesterol regulation, improved mental health, and reduced…

dra.carlafont · May 15, 2025 1,901 views
せきねとよこ
@toyochin · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 25, 2025 · 21 shares · 1,850 followers View post →
行田瑠魔⛄(化学屋さん)⛄
@yukidaruma358 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 23, 2025 · 21 shares · 998 followers View post →
松崎哲郎(
@nagaragawa79 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 23, 2025 · 21 shares · 1,613 followers View post →
花海澪(はなかいみお)♥️
@08hanakai · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 23, 2025 · 21 shares · 1,393 followers View post →
Mt.Fuji
@32_1_Maestoso · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 22, 2025 · 21 shares · 409 followers View post →
es-mig
@esumi_uoeh · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 21, 2025 · 21 shares · 2,898 followers View post →
xingchariot
@xingchariot · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Sep 1, 2025 · 21 shares · 251 followers View post →
クロエ@雑多垢
@yamagishi097654 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Aug 30, 2025 · 21 shares · 371 followers View post →
どらごん
@doragon113300 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 141 followers View post →
法匪の放屁⭐️
@KpFhd7WSalOp7ov · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 1,161 followers View post →
( ゚д゚) T A M A 産
@yastomohalumisa · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 1,727 followers View post →
がちゃん!⭐️
@SamuelA53340543 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 1,160 followers View post →
むし
@Hi_neu · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 1,243 followers View post →
籠入猫
@trashcantiglets · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 508 followers View post →
行田瑠魔⛄(化学屋さん)⛄
@yukidaruma358 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jul 1, 2025 · 21 shares · 998 followers View post →
薄花桜
@Usuha07 · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 21 shares · 79 followers View post →
波
@nami_haipho · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 21 shares · 162 followers View post →
あん肝 LOVE
@ankimolove_ · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 21 shares · 3,258 followers View post →
原 拓史
@haltaq · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 21 shares · 3,536 followers View post →
Kazuhiro Shiozaki
@KAZ_shiozaki · X

RT @esumi_uoeh: これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 21 shares · 3,063 followers View post →
es-mig
@esumi_uoeh · X

これは「高度侵襲・ストレス状態においては、全身の筋肉が分解されて各臓器の機能維持が行われる」という Figure これを見れば「サルコペニア(筋肉量減少)」で侵襲に対する生存率が低下するというのも一目瞭然です

Jun 30, 2025 · 65 likes · 21 shares · 2,898 followers View post →
Jon Ryan
@JonRyanCSP · X

RT @Strength4_Life: @saeboukglyn @logan_angie @LaterLifeTrain @thecsp @JonRyanCSP @PalingClaire @Claire_Minshull 1. https://t.co/DppjcsHdWS…

Dec 13, 2022 · 2 shares · 1,949 followers View post →
Strength For Life
@Strength4_Life · X

RT @Strength4_Life: @saeboukglyn @logan_angie @LaterLifeTrain @thecsp @JonRyanCSP @PalingClaire @Claire_Minshull 1. https://t.co/DppjcsHdWS…

Dec 13, 2022 · 2 shares · 11,548 followers View post →
Strength For Life
@Strength4_Life · X

@saeboukglyn @logan_angie @LaterLifeTrain @thecsp @JonRyanCSP @PalingClaire @Claire_Minshull 1. https://t.co/DppjcsHdWS 2. https://t.co/Fl9yr6fqBK 3. https://t.co/vScyNetMke. https://t.co/0wbC8lA7TT

Dec 13, 2022 · 11 likes · 2 shares · 11,548 followers View post →
Health Space Academia
@HS_Academia · X

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease. ¡A leer! https://t.co/IX1pdm0SuF ---

Jun 8, 2022 · 429 followers View post →
Strength For Life
@Strength4_Life · X

RT @Strength4_Life: 2a. Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/U7q1w1z9AF…

May 26, 2022 · 1 share · 11,548 followers View post →
Strength For Life
@Strength4_Life · X

2a. Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/U7q1w1z9AF https://t.co/nL9Ob9Ocz3

May 15, 2022 · 8 likes · 1 share · 11,548 followers View post →
歌島大輔@日本一の整形外科医YouTube(22万人)
@pedro0507 · X

■筋肉が多いと死亡率が低い理由はグリコーゲンの貯蔵が関係している? 骨格筋は臓器間クロストークを介して代謝を制御する。健康と疾病における役割 https://t.co/R6kdS6Dj5O

Jan 25, 2022 · 10,266 followers View post →
Solin L.R.
@SolinLujanRuz · X

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease - Journal of the American Medical Directors Association https://t.co/YelTOmjGJx

May 11, 2021 · 210 followers View post →
Prof. Biology
@ResearchBiology · X

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease: https://t.co/gX06PEim0x

May 8, 2021 · 614 followers View post →
Lalo Zavala
@Zedduardo1 · X

RT @hattersley4: Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https:…

Nov 8, 2020 · 6 shares · 170 followers View post →
Toppform Oslo
@Toppform_gym · X

RT @hattersley4: Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https:…

Oct 27, 2020 · 6 shares · 244 followers View post →
Kineblasto
@Kineblasto · X

RT @hattersley4: Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https:…

Oct 27, 2020 · 6 shares · 111 followers View post →
Ирина Баринова
@DAZy81 · X

RT @hattersley4: Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https:…

Oct 27, 2020 · 6 shares · 34 followers View post →
Milos Djuric
@FizioEdu · X

RT @hattersley4: Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https:…

Oct 27, 2020 · 6 shares · 316 followers View post →
Chris Hattersley
@hattersley4 · X

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease https://t.co/Z8n5H0JorF https://t.co/h9oLZZ9CcF

Oct 27, 2020 · 29 likes · 6 shares · 1,958 followers View post →
Histology
@histocasino · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 19, 2020 · 21 shares · 3,334 followers View post →
Pablo J. Marcos PhD.
@pablojmarcos · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 18, 2020 · 21 shares · 1,783 followers View post →
CMaxwell
@MitoFitNurse · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 18, 2020 · 21 shares · 262 followers View post →
PrAISED research team
@PrAISEDUoN · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 16, 2020 · 21 shares · 430 followers View post →
SHU_PAWPH
@SHU_PAWPH · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 15, 2020 · 21 shares · 466 followers View post →
Strength Training As You Age
@strengthANDage · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 1 followers View post →
Madhan Ramanathan
@sportsphysiouk · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 1,144 followers View post →
Koushik
@koushikphysio · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 523 followers View post →
Gustavo Humeres
@LicHumeres · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 371 followers View post →
Bhanu Ramaswamy OBE
@BhanuPhysio · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 1,188 followers View post →
María #SaldráElSol
@w3myrem · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 1,964 followers View post →
Scotty Butcher PhD
@TheStrengthJedi · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 2,065 followers View post →
Israel Garcia Z
@isgazu · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 269 followers View post →
Ирина Баринова
@DAZy81 · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 34 followers View post →
Sue Bridge
@Bridge1Sue · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 349 followers View post →
Hélène PhD
@HelenePhd · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 248 followers View post →
Dr VP Lakshmikanth
@doctorlaksh · X

RT @Strength4_Life: Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function!…

Mar 14, 2020 · 21 shares · 529 followers View post →
Strength For Life
@Strength4_Life · X

Muscle is a a critical physiological reserve in diseased states that supports immune, endocrine & metabolic function! ‘Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease’

Mar 14, 2020 · 30 likes · 21 shares · 11,548 followers View post →