PubHawk
November 2016 PMID 27351678

Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain.

Pavel Rodriguez, Wei Zhou, Douglas W Barrett, Wilson Altmeyer, Juan E Gutierrez, Jinqi Li, Jack L Lancaster, Francisco Gonzalez-Lima, Timothy Q Duong

Full text PDF Download social card

Mentions

148
Peak: 10 in Feb 2022
across 6 sources since Oct 2016

Extended reach

133,126
potential audience

Total likes

3,039

Video views

84,728

Mentions per month

Oct 2016 – Sep 2025

Where it's discussed

  • News102 articles
  • X / Twitter22 posts
  • Facebook11 posts
  • YouTube6 videos
  • Blogs5 articles
  • Reddit2 posts

AI synopsis

What people are saying

The discussion expresses positivity and curiosity, citing examples like the '7% memory improvement' and MRI results showing increased brain activity, with words such as 'genuinely curious' and phrases like 'worth reposting' that demonstrate both interest and engagement. The tone balances skepticism with recognition of potential, reflecting moderate impact overall.

AgreementModerate agreement

The posts generally support the study’s findings about methylene blue's potential cognitive benefits, with some recognizing its promise but noting the limited research scope.

InterestHigh interest

Discussions show high interest, as many posts mention specific cognitive improvements like memory and attention, and reference detailed MRI findings.

EngagementModerate engagement

Posts reflect moderate engagement, with references to scientific terms, questions about implications, and some sharing of related studies.

ImpactModerate impact

The overall discussion suggests a modest impact, primarily raising awareness about the research rather than advocating immediate application or widespread change.

Abstract in brief

  • The study aimed to examine how low-dose methylene blue affects sustained attention and memory in healthy adults, using MRI scans to track brain activity.
  • Twenty-six participants underwent attention and memory tasks before and after taking either methylene blue or a placebo, with results showing significant brain activity in regions related to these tasks.
  • Methylene blue administration improved response rates during memory retrieval by 7%, suggesting its potential benefits for cognitive enhancement in healthy individuals.
Read the full abstract

Top posts

Most liked on X and Bluesky
fdzaraf
@fdzaraf · X

健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した。 Pub 2016/6/28 https://t.co/tTY7T2ojCJ

Feb 13, 2022 · 46 likes · 11 shares · 13,080 followers View post →
京大魑魅魍魎大図鑑
@kyodai_meltdown · X

@Ig_A_ 本来の用途以外の使用は自己責任の範囲で！ https://t.co/BCNC1IUChh

Apr 16, 2021 · 1 like · 11,607 followers View post →
Travis Smith, D.O. FAAEM
@RosenelliEM · X

There are not a lot of human studies on Methylene Blue in humans for inflammation and memory. But here is one Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain - PubMed https://t.co/g5ewCXSVdR

Mar 5, 2025 · 1 like · 5,111 followers View post →
Nasser
@nasserdev · X

@nootroplanet @timesup_man https://t.co/oPMrVY7p9p Je viens de voir, effectivement je me suis trompé concernant la mémoire, y a une amélioration de 7% de la mémoire à faible dose, mais attention y a aucune mention d'énergie dans l'étude.

Jun 6, 2024 · 1 like · 3,097 followers View post →
Robert Raeder
@RobertRaeder · X

@whereisdaz Genuinely curious what your thoughts/opinions on this paper are… “methylene blue increased response in the bilateral insular cortex during a psychomotor vigilance task…associated with a 7% increase in correct responses during memory retrieval” https://t.co/WLPBQ67Hyw

Mar 14, 2022 · 1 like · 345 followers View post →
Agbnerh3
@Agbnerh3 · X

@AkrSakr 思い出しましたがメチレンブルーが短期記憶改善機能があるという，こんなタイトルの論文が数年前にありました。Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain https://t.co/2PV5sRhZ7T　わたしゃ評価不能なんでずかしさんに登場頂きたいです。

Jun 10, 2021 · 1 like · 141 followers View post →

All mentions

Travis Smith, D.O. FAAEM
@RosenelliEM · X

There are not a lot of human studies on Methylene Blue in humans for inflammation and memory. But here is one Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain - PubMed https://t.co/g5ewCXSVdR

Mar 5, 2025 · 1 like · 5,111 followers View post →
n/a
@pblover229 · X

Methylene blue smoothie. https://t.co/GCZrvp262U https://t.co/ow1WO0Zi8p https://t.co/p41dMMbWUt

Feb 19, 2025 · 65 followers View post →
Nasser
@nasserdev · X

@nootroplanet @timesup_man https://t.co/oPMrVY7p9p Je viens de voir, effectivement je me suis trompé concernant la mémoire, y a une amélioration de 7% de la mémoire à faible dose, mais attention y a aucune mention d'énergie dans l'étude.

Jun 6, 2024 · 1 like · 3,097 followers View post →
Robert Raeder
@RobertRaeder · X

@whereisdaz Genuinely curious what your thoughts/opinions on this paper are… “methylene blue increased response in the bilateral insular cortex during a psychomotor vigilance task…associated with a 7% increase in correct responses during memory retrieval” https://t.co/WLPBQ67Hyw

Mar 14, 2022 · 1 like · 345 followers View post →
マナマロン
@mmaarroonn1608 · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 16, 2022 · 11 shares · 814 followers View post →
Matsuineko
@matsuneko25 · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 16, 2022 · 11 shares · 1,940 followers View post →
マイ君
@maikun27 · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 14, 2022 · 11 shares · 2,711 followers View post →
せお®️
@theodore_1028 · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares · 158 followers View post →
pyokotan
@kotoranoshimobe · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares · 44 followers View post →
オレンジママ（脱原発に1票）
@HappyOrangeMama · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares · 1,609 followers View post →
石田修司☆
@hoikita7 · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares · 1,928 followers View post →
_24_com
@_24_com · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares · 1,497 followers View post →
宮島正
@yasuokajihei · X

RT @fdzaraf: 健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した…

Feb 13, 2022 · 11 shares View post →
fdzaraf
@fdzaraf · X

健康な人の脳において,経口メチレンブルーによる持続的な注意力と記憶力増強の神経相関を調べた。(前向きHIPAA準拠無作為化二重盲検プラセボ対照臨床試験) 低用量メチレンブルーは,持続的注意と短期記憶課題中の機能的MR画像活動を増加させ記憶検索を増強した。 Pub 2016/6/28 https://t.co/tTY7T2ojCJ

Feb 13, 2022 · 46 likes · 11 shares · 13,080 followers View post →
Agbnerh3
@Agbnerh3 · X

@AkrSakr 思い出しましたがメチレンブルーが短期記憶改善機能があるという，こんなタイトルの論文が数年前にありました。Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain https://t.co/2PV5sRhZ7T　わたしゃ評価不能なんでずかしさんに登場頂きたいです。

Jun 10, 2021 · 1 like · 141 followers View post →
京大魑魅魍魎大図鑑
@kyodai_meltdown · X

@Ig_A_ 本来の用途以外の使用は自己責任の範囲で！ https://t.co/BCNC1IUChh

Apr 16, 2021 · 1 like · 11,607 followers View post →
Maurice Preter MD
@DrMauricePreter · X

RT @DrMauricePreter: Worth reposting/rereading! Multimodal randomized Functional MR imaging of the effects of Methylene Blue in https://t.c…

Aug 1, 2020 · 2 shares · 990 followers View post →
5thAveConciergeMed
@PrivatHealth · X

RT @DrMauricePreter: Worth reposting/rereading! Multimodal randomized Functional MR imaging of the effects of Methylene Blue in https://t.c…

Jul 27, 2020 · 2 shares · 300 followers View post →
Maurice Preter MD
@DrMauricePreter · X

Worth reposting/rereading! Multimodal randomized Functional MR imaging of the effects of Methylene Blue in https://t.co/KKDuBA0beG #aging

Jul 27, 2020 · 2 shares · 990 followers View post →
R
@Caldodegalets · X

RT @caloriasvacias: Buscando info sobre el azul de metileno he encontrado este estudio doble ciego. AM (280 mg) ⬆️ la memoria a corto plazo…

Feb 23, 2020 · 1 share · 1,585 followers View post →
祝祥伝
@candrasan254 · X

備忘メモ 「頭がよくなる薬」が見つかる：米大学https://t.co/bXkW5JgXP8 　↓　元ネタ Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain https://t.co/gf1Botgzpf

Sep 10, 2019 · 29 followers View post →
constantpoesia
@constantpoesia · X

pesquisa de neurorradiologia feita com o azul de metileno comprovando a melhora da memória e da atenção no cérebro humano saudável. https://t.co/zCbM8IS8pe

Jan 20, 2019 · 126 followers View post →