July 2016 PMID 27404185

Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy.

Alison J Rodger, Valentina Cambiano, Tina Bruun, Pietro Vernazza, Simon Collins, Jan van Lunzen, Giulio Maria Corbelli, Vicente Estrada, Anna Maria Geretti, Apostolos Beloukas, David Asboe, Pompeyo Viciana, Félix Gutiérrez, Bonaventura Clotet, Christian Pradier

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Mentions

Peak: 9 in Jun 2021

across 5 sources since Jul 2016

Extended reach

171,555

potential audience

Total likes

206

Video views

35,565

Mentions per month

Jul 2016 – Sep 2025

Where it's discussed

X / Twitter16 posts
News16 articles
Facebook6 posts
YouTube2 videos
Blogs1 articles

AI synopsis

What people are saying

Overall, the social discussions reveal high interest and agreement with the study’s conclusions, exemplified by references to key studies like HPTN052 and the phrase 'U=U' to underline the significance of undetectable viral loads for transmission prevention. The tone indicates that participants view this research as impactful for both scientific understanding and practical application in HIV prevention.

AgreementModerate agreement

Most discussions support the findings that condomless sex with a virally suppressed partner greatly reduces HIV transmission risk.

InterestHigh interest

Posts demonstrate high interest, referencing multiple studies like HPTN052 and PARTNER1, and discussing implications for HIV prevention strategies.

EngagementModerate engagement

Some comments engage deeply by referencing scientific terms and the significance of undetectable viral loads, indicating active participation in the topic.

ImpactHigh impact

The discussions highlight how the research could influence HIV prevention policies and personal behaviors, emphasizing its real-world importance.

Abstract in brief

The study examines the risk of HIV transmission among serodifferent couples (where one partner is HIV-positive and on suppressive ART, and the other is HIV-negative) during condomless sex when the HIV-positive partner has a viral load under 200 copies/mL.
Conducted across Europe with 1166 couples, the study found that the actual risk of HIV transmission in this scenario is very low, supporting the effectiveness of ART in reducing transmission risk.
Phylogenetic analysis confirmed that most new HIV infections in HIV-negative partners originated from within the couple, emphasizing that condomless sex with a virally suppressed HIV-positive partner poses minimal transmission risk.]

Read the full abstract

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Yuri

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HIV-1 trans. New England Journal of Medicine, 375(9), 830-839. •Rodger, A. J., Cambiano, V., Bruun, T., Vernazza, P., Collins, S., van Lunzen, J.,... & PARTNER Study Group. (2019). Sexual activity without condoms and risk of HIV transmission in serodifferent couples when

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