Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases liver fat: https://t.co/OjvSxpBS1K https://t.co/pJ76tYJyMS Decreases insulin sensitivity: https://t.co/uLDbEVIPLC Increases inflammation: https://t.co/ngWk15DTNr
Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials.
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AI synopsis
What people are saying
The discussions reflect a keen interest in the health effects of different fats, with many emphasizing the benefits of PUFAs over saturated fats supported by meta-analyses; for instance, references to improvements in insulin sensitivity and blood glucose control highlight how wording and tone underline the perceived importance of these findings in dietary recommendations.
Most participants acknowledge the findings that polyunsaturated fats improve glucose and insulin regulation, and some even support replacing saturated fats with PUFAs.
Discussions are highly engaged, with many analyzing specific details like insulin sensitivity, effects of seed oils, and meta-analyses, indicating strong interest.
Participants reference studies, question methods, and compare fats, demonstrating active involvement and deeper understanding.
While some users recognize the significance of the research findings for dietary choices, the overall impact appears moderate as debates persist and evidence is contested.
Abstract in brief
- The study analyzed how different types of dietary fats and carbohydrates impact glucose and insulin regulation, with findings based on multiple controlled feeding trials involving adults.
- Replacing 5% of energy from carbohydrates with saturated fat (SFA) slightly reduced fasting insulin but didn't significantly change fasting glucose levels; swapping carbs for monounsaturated fats (MUFA) improved several key markers like HbA1c and insulin sensitivity.
- Substituting carbohydrates with polyunsaturated fats (PUFA) generally lowered HbA1c, fasting insulin, and improved insulin resistance, while replacing SFA with PUFA led to decreased blood glucose, indicating healthier effects.]
Top posts
Most liked on X and BlueskyReplacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish, liquid veg oil) improves glucose, insulin, insulin resistance also improves lipids. same foods optimize all factors meta of >100 RCTs https://t.co/cvPd9dafLA
Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans fat, fiber ✔️ polyunsat fat (PUFA) beat carbs (mainly refined), saturated fat lowered fasting glucose, HbA1c, HOMA-IR, insulin secretion https://t.co/cvPd9dafLA
His other claim that linoleic acid decreases insulin sensitivity is not supported by human evidence… in fact the opposite may be true
Meta-analysis of 100 RCTs: "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity." h/t: @NutritionMadeS3 https://t.co/zH0xFndeYT
@Veganella_ Did he really expect swapping out carbs for saturated fat would reduce his fasting glucose? Why? Do these peeps do even basic research? Doi:10.1371/journal.pmed.1002087 https://t.co/X05Z7ly6Ry
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RT @cremieuxrecueil: As always, the best diet is just the one that works with you. Sources: https://t.co/UPOtwdeAbX https://t.co/Q7mCWKC…
RT @cremieuxrecueil: As always, the best diet is just the one that works with you. Sources: https://t.co/UPOtwdeAbX https://t.co/Q7mCWKC…
RT @cremieuxrecueil: As always, the best diet is just the one that works with you. Sources: https://t.co/UPOtwdeAbX https://t.co/Q7mCWKC…
As always, the best diet is just the one that works with you. Sources: https://t.co/UPOtwdeAbX https://t.co/Q7mCWKCD51
@siobhan_huggins @dylanarmbruste3 @HHSGov @NBCNews @SecKennedy See also: https://t.co/FDN6NX6oEa
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
@ChrisMasterjohn Am I imagining something or is this study showing PUFAs increase insulin secretion??? https://t.co/EMV361ffIi
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
RT @BioLayne: Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases…
Yes, the data shows very clearly, replacing seed oils like canola, safflower, sunflower etc with saturated fat... Increases liver fat: https://t.co/OjvSxpBS1K https://t.co/pJ76tYJyMS Decreases insulin sensitivity: https://t.co/uLDbEVIPLC Increases inflammation: https://t.co/ngWk15DTNr
@Lacrisisdehoy @AriesTerron Ahí están todas las fuentes que pude encontrar del extracto https://t.co/aVwa3LkxoO https://t.co/ROUdTBQpjo https://t.co/DYTfv85ZTC https://t.co/HfGh52GwpN https://t.co/1oXPYHEuR3 https://t.co/hKfVVFXi1x https://t.co/0qpNg5ZcVy https://t.co/3T9WUBsNJ8
@krissasse @withered_haze @cneezy007 @MsMelChen More data ... * Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials https://t.co/HBbcxoVb1y
@therealjimbbq @MohammedAlo @calmdiscuss Relative to PUFAS he is right: https://t.co/tN8n08YCyv
@Mqsley @PrayTheRosary12 @nypost Seed oils are not associated with T2DM or obesity in humans: https://t.co/6EuJ6zpebq https://t.co/5nxffMW4cD https://t.co/q8nDFmsxVZ https://t.co/TxpdhdFGOx https://t.co/jh7eA6b6zi
@_coach_al @drcateshanahan Further, such a swap (adding in butter in place of seed oils), with everything else maintained, would most likely have a negative effect on metabolic health. https://t.co/vPyG2p728T https://t.co/tN8n08YCyv
Research shows that shifting 5% of dietary energy from carbs or saturated fats to polyunsaturated fats can reduce HbA1c by 0.1%, aiding in blood sugar control. https://t.co/Y20a2ljwC2 #Diabetes #HealthyFats #BloodSugar
@6mmHls @theproof @drcateshanahan This topic has been studied to death. The research on dietary fat goes back decades. As for insulin sensitivity, see this meta-analysis and the included studies. https://t.co/ESG48Vp2DN
@Bellin546367 @RMiller77489648 Inflammation: https://t.co/Wi9pgSWI0K Glycemia: https://t.co/KeHn0k1TF3 https://t.co/j4smiv0mOh https://t.co/Bwt6568I8D https://t.co/2Hgj5yQtN3 https://t.co/0VhhmLbmzB https://t.co/2o6SqeyTuq https://t.co/V3XOlqASvg https://t.co/8RN9yJ3Maa Cvd: https://t.co/qcxUyeG9RH
RT @Alan_Watson_: @Veganella_ Did he really expect swapping out carbs for saturated fat would reduce his fasting glucose? Why? Do these p…
@Veganella_ Did he really expect swapping out carbs for saturated fat would reduce his fasting glucose? Why? Do these peeps do even basic research? Doi:10.1371/journal.pmed.1002087 https://t.co/X05Z7ly6Ry
@thereal_truther If anything polyunsaturated fats seem to be protective for glucose homeostasis https://t.co/ESG48Vp2DN https://t.co/BGKw0YpHHt
@vniskasa @SentientBlobBob @stathitriadis @DavidMe17661988 @exfatloss @TraderMick_ @carnivorecringe But more LA is supposed to help insulin sensitivity. https://t.co/3BdioHGMcE https://t.co/Yh0dE9nGPf https://t.co/QzUp1NAzE6 https://t.co/QzUp1NAzE6 Furthermore it helps body composition: https://t.co/et3Zw7PhJp
@Jerwgar3 I'm not granting that humans ate a carnivore diet for 90% of history. Adding mechanistic speculation to an anecdote doesn't make the inference likely. I can speculate too. PUFA improves glucose tolerance compared to SFA (https://t.co/9pZDkwvtfy). Maybe this reduces sunburn risk.
@Jackson_Haen84 @TavisPiattoly This is why I can't take dieticians seriously. Reposting research from those who've admitted research fraud. It's basically an industry advertisement. Your claim: "PUFAs improve HbA1c... HOMAIR [sic]" from 27434027 (https://t.co/VNoHpnaJqH) Their statement: "Our investigation https://t.co/hKSpEYnYph
@fellowshipnate @LORASHIEL @ScepticalDoctor That’s not true bc there’s research isolating the effects of different fats. Effects of different fats & oils on cardiovascular risk factors https://t.co/TsQczqg4LR Effects of fat type (PUFA, MUFA, SFA) and carbohydrate on glucose homeostasis https://t.co/ESG48Vp2DN
RT @mikepaulwill: @paulsaladinomd This guy talks more
@paulsaladinomd This guy talks more
@TarbuckSam @brian_t_muldoon @BenBikmanPhD Lol the seed oils. It’s funny bc PUFA seems to improve glucose homeostasis when replaced isocalorically w SFA. https://t.co/ESG48Vp2DN
@TuckerGoodrich @foundmyfitness @AnthonyLewayne @fmfclips @WHO Looks like you’re not familiar with the meta-analytic data: https://t.co/hIqUQlB1kr ”In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity.”
@SamaHoole Yea, because saturated fats hinder glucose homeostasis (which is of clinical importance to people w/ diabetes) particularly in comparison to PUFA, calorie for calorie. https://t.co/ESG48Vp2DN
@LowCarbEyeDoc @SentientBlobBob @DoctorTro I didn’t disagree with Tro about his original post above about replacing carbs with saturated fat because there is evidence of small benefits from certain isocaloric substitutions. But what he left out is that PUFA appears even better than saturated fat: https://t.co/9PkIHum7YR
@thalesnemo @kevtharris @shelly_187 Is that why swapping red meat for legumes lowers fasting blood glucose and fasting insulin https://t.co/viu3V1C9lL why swapping saturated fat with polyunsaturated fat reduces fasting blood glucose? https://t.co/ESG48Vp2DN
@paulsaladinomd Significant negative effects like reductions in cardiovascular events https://t.co/CTbEzOUEm7 and improvements in glucose homeostasis? https://t.co/ESG48Vp2DN
@Reed_Frost1990 @SeedOilDsrspctr Is that why PUFA improves glucose homeostasis compared to SFA https://t.co/ESG48VpAtl why vegetable oils improve lipids https://t.co/TsQczqgCBp and why intakes & tissue representation of linoleic acid predict lower mortality of all sorts of diseases? https://t.co/6DGPUWKnaB
@BioLayne Here are the results. You can see everything is just PUFA. Study link here: https://t.co/wyKyPzmCk7 Fun fact about this study. MUFA leads to higher fasting insulin than SFA or PUFA. Which is great, since I’ve been banging on MUFA. https://t.co/LCoUALETXm
@raphaels7 But if you want to try, you can peruse some material: https://t.co/uNTPrOebi9 https://t.co/9Xo0DwCZKd https://t.co/0VhhmLaOK3 (Not a true clinical trial) https://t.co/gqzLerGoOw https://t.co/3SlaK0xEa5 https://t.co/j7Yoe55ID0
@Bittner5Edward @ScepticalDoctor @VectorBosonX (3/5) Regarding insulin, SFA is categorically the worst fat: https://t.co/EVPHSFpgh6.
@Lunatic__Fringe @TamarHaspel oops. https://t.co/H6rlukcup9
@lcmail2 @TamarHaspel https://t.co/H6rlukcup9
@robertlufkinmd This review study looks interesting https://t.co/gNtEw3uJH2
Unsaturated Fats cause Insulin Resistance?? #shorts https://t.co/rpHAKXzNa9 via @YouTube
@AnimalEndurance Same thing with insulin sensitivity: https://t.co/tN8n08Zao3
@DimitriRadoux @richcollins @ZahcM @Gearoidmuar @DIY_Tardis @ScepticalDoctor So you think only food intervention studies are convincing. meta-analysis of RCTs has shown that substituting PUFAs for SFA/carbs and fructose for glucose can lower hba1c. So enjoy PUFAs & fructose. https://t.co/8qvINjYGcw https://t.co/ZExqZayArc
@Olicsa06 @sciencebyjae Another meta-analysis for you. https://t.co/Cu4JcoI3iZ
RT @theproof: @tvc310 @Drlipid Probably because there is a common denominator. Saturated fats raise ApoB and reduce insulin sensitivity. T…
RT @theproof: @tvc310 @Drlipid Probably because there is a common denominator. Saturated fats raise ApoB and reduce insulin sensitivity. T…
@tvc310 @Drlipid Probably because there is a common denominator. Saturated fats raise ApoB and reduce insulin sensitivity. This is widely established. https://t.co/tN8n08Zao3
@ChrispLMarshall @sos_intern @jonnyob @Crzy_Diamond @holmanm https://t.co/qRqH1Gmz3D We also see beneficial effects on glucose & insulin with polyunsaturated fats
The modern boogie-man of the dogmatic keto people and the carnivore dieters is that seed oils are the problem. This meta-analysis of human control trials concludes polyunsaturated fats (like seed oils) can actually be shown to improve insulin sensitivity. https://t.co/sPNQ1MOPsD
@iwantthescience @ReynardtDeminey @ScepticalDoctor Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials https://t.co/tN8n08Zao3
@PeterAttiaMD Why don’t you ever talk about the role saturated fatty acids play in insulin resistance? https://t.co/40ux85hq47
@raphaels7 @Tom_Babington1 Do you think that's better than this one on hard outcomes in humans showing PUFA is better than SFA for insulin sensitivity? https://t.co/nnyTbcd0dU By the way, even in rodents, this one found saturated fat & not omega 6 caused IR: https://t.co/wjvEe326Ui
@DimitriRadoux Saturated fats increasing insulin resistance is not a new learning. Summarised by this meta analysis of RCTs. “Replacing SFA with PUFA significantly lowered glucose, HbA1c, C-peptide, and HOMA.” https://t.co/tN8n08Zao3
@nicknorwitz Be better off swapping calories from SFA with PUFAS https://t.co/lJp7cbzT0G https://t.co/NvNkTFf5II https://t.co/X4Nq3IK83g
@krosenque @ProfTimNoakes Or here: "Replacing carbohydrate with PUFA significantly lowered HbA1c (-0.11%; -0.17, -0.05) and fasting insulin (-1.6 pmol/L; -2.8, -0.4)." https://t.co/5wBY2lUZpr
@Af_donnerwetter @303Magnus @skaggandreas @hammerotass @Gummitarzan81 @KarlbergErik @AgnesWold @modiri_navid Byte av mättat det mot fleromättade fetter höjer insulinkänsligheten https://t.co/jUxrAeJLW6 https://t.co/reTw1HDruQ
@italia_gus Yep both. PUFAs seem better for IR https://t.co/tN8n08Zao3
Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials - PubMed https://t.co/udDDI7yv3P
@raphaels7 Interestingly insulin sensitivity increases in these models, which is what causes the obesity to occur. You can do the same to insulin sensitivity in people using linoleic acid, as in https://t.co/3IZjZFeafe I wonder what that will cause?
We also have evidence that replacing SFA with unsaturated fat (especially PUFA) improves blood-glucose control, insulin secretion, and insulin sensitivity https://t.co/0k76Mw4myn
@robertlufkinmd https://t.co/S8zqgD5bvP
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
@kafakullanin @kardiyobey https://t.co/iSHFKidLTQ
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @Nutradvance: Meta-analysis of 100 RCTs: "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen wi…
RT @Nutradvance: Meta-analysis of 100 RCTs: "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen wi…
RT @Nutradvance: Meta-analysis of 100 RCTs: "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen wi…
Meta-analysis of 100 RCTs: "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity." h/t: @NutritionMadeS3 https://t.co/zH0xFndeYT
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
@SeedOilDsrspctr Not sure what to make of this ...' these findings support benefits of increasing consumption of vegetable oils and spreads, nuts, fish, and vegetables rich in unsaturated fats (e.g., avocado), in place of either animal fats ...' https://t.co/HtDWEKGZZM
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
@TuckerGoodrich @JayneReesBuxton @SeedOilDsrspctr How would you critque this? '...these findings support benefits of increasing consumption of vegetable oils and spreads, nuts, fish, and vegetables rich in unsaturated fats, in place of either animal fats ...' https://t.co/HtDWEKGZZM
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
RT @NutritionMadeS3: Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish,…
Replacing any macro incl. saturated fat (fatty meat, butter, lard) with polyunsaturated fat (nuts, seeds, fatty fish, liquid veg oil) improves glucose, insulin, insulin resistance also improves lipids. same foods optimize all factors meta of >100 RCTs https://t.co/cvPd9dafLA
@AsarCadyn @NutritionMadeS3 Zero? Maybe 3 reviews can make you change your mind. https://t.co/gJGoAiQoFW https://t.co/gOxatksiWJ https://t.co/9UYlfsxVkH
RT @BioLayne: His other claim that linoleic acid decreases insulin sensitivity is not supported by human evidence… in fact the opposite may…
His other claim that linoleic acid decreases insulin sensitivity is not supported by human evidence… in fact the opposite may be true
@PenelopeFigtree Calorie for calorie swaps with dietary saturated fat, dietary monounsaturated fat and dietary PUFAs depending on the study. The meta-analysis looked at several different isocaloric substitutions. https://t.co/tN8n08Zao3
@TariroAnton @MathieuChiasson Very. https://t.co/tN8n08Zao3
@connected_dad @MasalaFry69 @fire_bottle https://t.co/zkX9aFBRTW
@AlexJLeaf Calories equated, are you of the view that different types of fat (saturated, MUFAS, PUFAS) affect insulin resistance equally? https://t.co/g9KMDEua75
@EinAuf @BenRavenPDF @sirpushalot @EricG1247 @DataDrivenMD I'll show you mine if you show me yours. "substituting carbohydrate and saturated fat with a diet rich in unsaturated fat, particularly polyunsaturated fat, was beneficial for the regulation of blood sugar" https://t.co/pkWWE7JU8a
@healthcoachkait Having said that, if one of your goals is to reduce insulin resistance & improve overall health, maybe you could do an article on which spreads are highest in PUFAs. https://t.co/nnyTbcd0dU https://t.co/9OxoW0RMsN
RT @theproof: @ScepticalDoctor Weight loss seems to be the most important factor when it comes to managing T2D. However, there is data to s…
RT @theproof: @nucleifitness @DoctorTro For data on saturated fat read this meta analysis of intervention studies. https://t.co/tN8n08H19V
https://t.co/nnyTbbVXbU
@ScepticalDoctor @theproof https://t.co/nnyTbbVXbU
@ScepticalDoctor Weight loss seems to be the most important factor when it comes to managing T2D. However, there is data to suggest saturated fat consumption can exacerbate insulin resistance (independent of calories compared to other fats). https://t.co/tN8n08H19V
RT @theproof: @nucleifitness @DoctorTro For data on saturated fat read this meta analysis of intervention studies. https://t.co/tN8n08H19V
@nucleifitness @DoctorTro For data on saturated fat read this meta analysis of intervention studies. https://t.co/tN8n08H19V
@DoctorTro @andyswarbs Not sure about that! Greger is as much as your colleague as he is mine. I’ve never met him. Anyhow - you’re cascading into different territory now. Re: dietary fats, as that seems to be where you’re going, I’ll leave this here: https://t.co/tN8n08H19V
@TuckerGoodrich @bruno_crocco @MrBillyBob2 @virtahealth @davidludwigmd @DikemanDave Thanks — and for any unbiased people out there, if that is even a thing, allow me to present the entirety of the medical literature which says the exact opposite in regards to PUFA vs saturated fat.
@SamiViik @hsfi @ValioFi https://t.co/RVSIPXlNY8
@Chandle74418127 @MichelleHurnRD Even if we forget epidemiology,we have RCT data showing that PUFA improves blood glucose, HbA1c, and insulin sensitivity when replacing SFA https://t.co/n4lkb5EQzy Then there's the beneficial effects of PUFA vs SFA on liver fat accumulation. https://t.co/o9je3sV2XU
@Meritorious_L @Mia_Tortilla007 @JohnConstas Doesn't appear to be the case https://t.co/n4lkb5EQzy
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
This recent meta analysis and systematic review suggest replacing carbohydrates with SUFA does NOT really lower blood glucose levels. However, replacing SFA with PUFA significantly lowered glucose, HbA1c, C-peptide, and HOMA. https://t.co/UiVzSjqQFI
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
RT @NutritionMadeS3: Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans f…
Best nutrient for glucose metabolism/diabetes? ▶️ meta-analysis of 109 RCTs ▶️ isocaloric ▶️ matched protein, trans fat, fiber ✔️ polyunsat fat (PUFA) beat carbs (mainly refined), saturated fat lowered fasting glucose, HbA1c, HOMA-IR, insulin secretion https://t.co/cvPd9dafLA
RT @Plant_proof: @MichaelMindrum I would posit it’s neither. It’s driven by an excess of calories and if we were to pin it on any particula…
@CarnivoreMD @drmarkhyman Funny that in clinical intervention studies (in humans not rats) replacing polyunsaturated fat with saturated fat increases insulin resistance. https://t.co/tN8n08H19V
@MichaelMindrum I would posit it’s neither. It’s driven by an excess of calories and if we were to pin it on any particular nutrient - it would be saturated fat. https://t.co/tN8n08H19V
@thealexmarquis Seed oils and obesity/ diabetes: https://t.co/dFSrzcCexy https://t.co/iKw0LIum6G https://t.co/aq12iPE3Jd https://t.co/cSsKPv34ki https://t.co/piLplZ6kTI
RCT SRMA, regarding macronutrients and insulin-glucose homeostasis. SFA and CHO about equivalent, PUFA better, small effects overall. https://t.co/tB4CEnyPWD
He then quotes a paper that is so bad that it's actually funny. Just the usual garbage about PUFA causing inflammation (nope) https://t.co/hVLEhvTzwv https://t.co/FXMjhE78sb https://t.co/Tg1TKfdeIb and insulin resistance (nope) https://t.co/n4lkb5EQzy https://t.co/SDCHzvDnQh
@twitevit @DaveKeto Key is sat fats super low with good amounts of PUFas - walnuts, flax , chia etc. That really helps insulin sensitivity. https://t.co/tN8n08H19V
RT @The_Nutrivore: LA/PUFA and glycemic control: RCTs https://t.co/kUrqZzbjOO Epi https://t.co/iQbXQPem5i LA/PUFA wins outright, and is…
@fbrown2014 @juliannejtaylor @DrPaulMason PUFA (seed oils) also decrease insulin resistance. https://t.co/JYvBnpFUUY
@Alecsplaining @kevinnbass @The_Nutrivore Mainly saturated fat. Good meta analysis comparing differential effect of fats here : https://t.co/tN8n08H19V
RT @The_Nutrivore: LA/PUFA and glycemic control: RCTs https://t.co/kUrqZzbjOO Epi https://t.co/iQbXQPem5i LA/PUFA wins outright, and is…
@MyNutritionSci If saturated fat, MUFA, starch and sugar collectively count as "a particular nutrient", then, at least when compared to PUFA, yes
LA/PUFA and glycemic control: RCTs https://t.co/kUrqZzbjOO Epi https://t.co/iQbXQPem5i LA/PUFA wins outright, and is preferable to MUFA or SFA for glycemic control and/or T2DM incidence. 3/n
@FoodFirst_Ty https://t.co/n4lkb5EQzy BuT PuFaS CaUsE InSuLiN ReSiStAnCe
@Bjorn_the_Beefy https://t.co/dFSrzckD8Y https://t.co/iKw0LIcKI6 https://t.co/aq12iPVEAL https://t.co/cSsKPuLsVI https://t.co/piLplZnVLg
@MarkBski @nutritionclari1 @SideHstleLife @BreatheLesss @tednaiman https://t.co/Glz8DSHYo3 https://t.co/HMNO2k8YEq https://t.co/uXrH0081Ce https://t.co/mQL933bk8x https://t.co/RP4F6hfh68
@CarnivoreMD Lol https://t.co/0k76Mw4myn
@CarnivoreMD https://t.co/tN8n08H19V Translated to foods, these finding support increased consumption of vegetable oils and spreads, nuts, fish, and vegetables rich in unsaturated fats (e.g., avocado), in place of either ani- mal fats or refined grains, starches, and sugars.
RT @Plant_proof: RCT feeding trials looking at different fats and insulin resistance. @CarnivoreMD please share a higher form of evidence t…
RT @Plant_proof: RCT feeding trials looking at different fats and insulin resistance. @CarnivoreMD please share a higher form of evidence t…
RCT feeding trials looking at different fats and insulin resistance. @CarnivoreMD please share a higher form of evidence that susbatntiates your theory that PUFAs cause insulin resistance. https://t.co/tN8n08H19V
@CarnivoreMD is back peddling on carbohydrates causing insulin resistance. A noble thing to say he got wrong. But he’s now trying to find another scapegoat - PUFAs? Where’s the human evidence Paul? https://t.co/lJp7cbQW2G
@kevinnbass @CarnivoreMD I’ll get ball rolling: https://t.co/lJp7cbQW2G
@lowcarbGP https://t.co/dFSrzckD8Y https://t.co/iKw0LIcKI6 https://t.co/aq12iPVEAL https://t.co/cSsKPuLsVI https://t.co/piLplZnVLg
@EAllen0417 That’s a lot of absolute saturated fat and would be a weird diet for a human. Other studies show polyunsaturated fats are able to increase insulin sensitivity. https://t.co/lJp7cbQW2G
Cool story. https://t.co/XywkNMf1kN https://t.co/pNPSliud2c https://t.co/RTAyJ4x7r0 https://t.co/uGqRFmgACv https://t.co/SIHBzp9kX7 https://t.co/9n5YlY88hR https://t.co/OgfHMYp5DE https://t.co/psnyrsOJZv https://t.co/smAr08Bn2T https://t.co/YKzsfUEroL https://t.co/cpr92VImOk
@oddvarsandvin @larsms @kariannesve Nei, det snakkes om både lipotoksisitet og glukotoksisitet. Type fett spiller også en rolle. https://t.co/yNyRp9B4zE
RT @Nutrirojo: @Somatotropina2 @drgorka_vazquez @MarcoGomezMD No creo que sea un demonio pero si parece que cuando se sobrealimenta(algo mu…
@Somatotropina2 @drgorka_vazquez @MarcoGomezMD No creo que sea un demonio pero si parece que cuando se sobrealimenta(algo muy común actualmente) genera más perjuicio en grasa hepática y en sensibilidad a la insulina: https://t.co/nnCuH4dqdJ https://t.co/SBDA7o37sP https://t.co/8y7mw7DSvv
@PeterFaberSP @Meat_Matter_Pod If you avoid highly processed food,you also avoid SFAs.Yes,that are unrealistic conditions but the point is that SFAs seem to be worse than UFAs,at least when you overconsume it https://t.co/nnCuH4dqdJ And in isocaloric conditions: https://t.co/8y7mw7DSvv
Efectos de la sustitución isoenergetica de CHO,PUFAs,MUFAs y SFAs en el control glucemico y la sensibilidad a la insulina,metaanalisis https://t.co/8y7mw7DSvv https://t.co/tUc1CXEAJ3
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