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Int J Radiat Oncol Biol Phys October 2016 PMID 27478165

Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials.

Jayant S Vaidya, Max Bulsara, Frederik Wenz, Nathan Coombs, Julian Singer, Stephen Ebbs, Samuele Massarut, Christobel Saunders, Michael Douek, Norman R Williams, David Joseph, Jeffrey S Tobias, Michael Baum

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Mentions

11
Peak: 1 in May 2016
across 4 sources since May 2016

Extended reach

2,676
potential audience

Total likes

2

Video views

384

Mentions per month

May 2016 – Jul 2021

Where it's discussed

  • Facebook5 posts
  • X / Twitter3 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a recognition of the promising results, with comments like 'Reduced mortality with targeted radiotherapy' indicating awareness of the article's key findings, and users referencing the potential for safer, more effective treatments. Words like 'reduced mortality' and phrases such as 'targeted radiotherapy' demonstrate a focus on clinical benefits, contributing to the overall moderate positive stance and engagement with the research's implications.

AgreementModerate agreement

Most discussions seem to acknowledge the positive findings regarding mortality reduction, indicating general agreement with the study's implications.

InterestModerate interest

While the discussions are brief, mentioning reductions and targeted therapy suggests moderate interest in the potential clinical impact.

EngagementModerate engagement

Participants reference the core concepts of the publication and use phrases like 'reduced mortality' and 'targeted radiotherapy,' showing some depth of engagement with the topic.

ImpactModerate impact

The emphasis on mortality reduction and treatment safety points to a meaningful impact in future treatment considerations, although the discussion remains somewhat superficial.

Abstract in brief

  • The meta-analysis of nine randomized trials found that partial breast irradiation (PBI) is associated with lower non-breast cancer and overall mortality rates at 5 years compared to whole-breast irradiation (WBI), with a roughly 25% reduction in relative terms.
  • There was no significant difference in breast cancer-specific mortality between PBI and WBI, indicating that PBI does not increase the risk of cancer recurrence or death from breast cancer.
  • Overall, the results suggest that for selected patients, using PBI instead of WBI may be a safer treatment option that reduces the risk of mortality without compromising cancer control.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Prof Jayant Vaidya
@jsvaidya · X

@drkevinknopf @PhilosopherMD1 @SorenBentzen Reduced mortality with targeted radiotherapy https://t.co/DOkY431f1o

Apr 9, 2020 · 1 like · 1,084 followers View post →
Prof Jayant Vaidya
@jsvaidya · X

RT @radoncpub: Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials https://t.c…

Jul 1, 2021 · 1 share · 1,084 followers View post →

All mentions

Prof Jayant Vaidya
@jsvaidya · X

RT @radoncpub: Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials https://t.c…

Jul 1, 2021 · 1 share · 1,084 followers View post →
Rad Onc Commentary
@radoncpub · X

Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials https://t.co/dt97wjJcu0

Jun 30, 2021 · 1 share · 120 followers View post →
Prof Jayant Vaidya
@jsvaidya · X

@drkevinknopf @PhilosopherMD1 @SorenBentzen Reduced mortality with targeted radiotherapy https://t.co/DOkY431f1o

Apr 9, 2020 · 1 like · 1,084 followers View post →