The discussions reflect a generally positive outlook on the article, with comments praising early trial data and the potential benefits of viscoelastic testing, such as in statements like 'In the first 17 RCTs, TEG/ROTEM decreased mortality,' and references to authoritative reviews and references on the topic. This tone and choice of wording reveal optimism about the clinical value of these methods and suggest they may influence future guideline changes.
AgreementModerate agreement
Most comments recognize the promising results of viscoelastic testing like TEG/ROTEM, especially noting early data suggesting mortality reduction.
InterestModerate interest
The discussions show a moderate level of interest, with users engaging in meaningful conversations about the evidence and potential applications.
EngagementModerate engagement
Posts demonstrate active engagement, referencing studies, highlighting the significance of the results, and citing additional sources.
ImpactModerate impact
Participants believe that TEG/ROTEM could have a notable impact on clinical practice, particularly in reducing blood product use and improving patient outcomes.
Abstract in brief
This review evaluates whether using Thromboelastography (TEG) or Thromboelastometry (ROTEM) to guide blood transfusions improves outcomes like mortality and bleeding in patients with severe bleeding and coagulopathy, compared to standard care or clinical judgment.
The researchers analyzed data from multiple randomized controlled trials (RCTs) up to January 2016, including studies from various medical databases, focusing on the effectiveness and potential harms of TEG/ROTEM-guided transfusions.
Overall, the review aims to determine if TEG or ROTEM provides a significant benefit over traditional methods by examining trial results, considering bias, performing statistical analyses, and updating previous findings from 2011 and 2016.
Perhaps the most damning argument against 1:1:1 is the success of viscoelastic testing
Early data make TEG/ROTEM look good
Its not definitive, but in the first 17 RCTs, TEG/ROTEM decreased mortality
https://t.co/Q0y3wzdYMM
Cochrane Anaesthesia & Emergency and Critical Care
@Cochrane_ACE · X
Our top-cited Emergency and Critical Care review of 2️⃣0️⃣1️⃣8️⃣ assessed TEG and ROTEM-guided transfusion in pt with bleeding https://t.co/5cLvgwGD9w
These strategies may ⬇️ need for blood products+improve morbidity, but further evidence on broader populations is needed #CochraneACE
This review evaluates whether using Thromboelastography (TEG) or Thromboelastometry (ROTEM) to guide blood transfusions improves outcomes like mortality and bleeding in patients with severe bleeding and coagulopathy…
This review assesses whether Thromboelastography (TEG) or Thromboelastometry (ROTEM) guide blood transfusions better than standard care in bleeding patients, analyzing multiple RCTs up to 2016 for effectiveness and…
This presentation examines whether thromboelastography (TEG) and Rotem improve blood transfusion outcomes in bleeding patients, comparing these methods to standard care based on randomized controlled trials and recent…
Perhaps the most damning argument against 1:1:1 is the success of viscoelastic testing
Early data make TEG/ROTEM look good
Its not definitive, but in the first 17 RCTs, TEG/ROTEM decreased mortality
https://t.co/Q0y3wzdYMM
Cochrane Anaesthesia & Emergency and Critical Care
@Cochrane_ACE · X
Our top-cited Emergency and Critical Care review of 2️⃣0️⃣1️⃣8️⃣ assessed TEG and ROTEM-guided transfusion in pt with bleeding https://t.co/5cLvgwGD9w
These strategies may ⬇️ need for blood products+improve morbidity, but further evidence on broader populations is needed #CochraneACE
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