Proc Natl Acad Sci U S A September 2016 PMID 27638206

Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes.

Ruiqi Huang, Andrew J O'Donnell, Jessica J Barboline, Todd J Barkman

Mentions

20
Peak: 2 in Feb 2019
across 4 sources since Feb 2019

Extended reach

316,553
potential audience

Total likes

6,576

Video views

271,451

Mentions per month

Feb 2019 – Aug 2025

Where it's discussed

  • News9 articles
  • X / Twitter5 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions emphasize caffeine's role as a plant defense mechanism and its convergent evolution across multiple species, using words like 'great example' and expressions of curiosity, which underscore a moderate but meaningful engagement with the study's findings and implications.

AgreementModerate agreement

Most discussions acknowledge and appreciate the significance of the research, with comments highlighting caffeine's evolutionary role and its diversity across species.

InterestModerate interest

Posts demonstrate moderate interest, especially in the idea of convergent evolution and the multiple plant sources of caffeine, which are intriguing to the audience.

EngagementModerate engagement

Participants engage by sharing insights about caffeine’s biological functions and suggesting educational discussions, indicating a meaningful level of engagement.

ImpactModerate impact

The discussions suggest that the article has educational and scientific importance, with potential to influence understanding of plant evolution and biochemical diversity.

Abstract in brief

  • Convergent evolution of caffeine in plants has occurred multiple times independently through different biochemical pathways, using either caffeine synthase or xanthine methyltransferase-like enzymes.
  • This process is driven by the cooption of ancient genes, some maintained for over 100 million years, which were repurposed for caffeine biosynthesis through minimal genetic mutations.
  • The study highlights that the specific enzymes and pathways used by different plant species are not predictable based on their evolutionary relatedness, indicating a high level of biochemical diversity in caffeine production.

Top posts

Most liked on X and Bluesky
Lyman Stone 石來民
@lymanstoneky · X

the weird thing about caffeine is that you can get it from so many places. like a dozen plant species all *independently evolved* their caffeine production capabilities! https://t.co/Ox9eXScQPT

Oct 19, 2022 · 38 likes · 37,768 followers View post →
Chris Graham
@DrCGraham · X

The evolution of caffeine in tea, coffee and chocolate is a great example of convergent evolution that students might be prompted to think about (or even discuss!) outside of lessons. Here's a link to the paper: https://t.co/OMIyQJlNn7.❓Does anyone have any other suggestions❓/5

Apr 21, 2023 · 6 likes · 584 followers View post →
Scientific Update
@SciUp · X

Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes https://t.co/FH8pNNNh3N https://t.co/UeI8908zdO

Feb 23, 2019 · 3 likes · 1 share · 2,224 followers View post →
Exaptive
@exaptive · X

RT @SciUp: Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes https://t.co/FH8pNNNh3N https://t.co/UeI890…

Feb 23, 2019 · 1 share · 4,366 followers View post →

All mentions

Being Human
@mr_being_human · X

@elonmusk @WallStreetSilv Caffeine is most likely meant to be a natural pesticide that plants use for defense and pollination. https://t.co/XKZuxJX9ve.

Apr 22, 2023 · 157 followers View post →
Chris Graham
@DrCGraham · X

The evolution of caffeine in tea, coffee and chocolate is a great example of convergent evolution that students might be prompted to think about (or even discuss!) outside of lessons. Here's a link to the paper: https://t.co/OMIyQJlNn7.❓Does anyone have any other suggestions❓/5

Apr 21, 2023 · 6 likes · 584 followers View post →
Lyman Stone 石來民
@lymanstoneky · X

the weird thing about caffeine is that you can get it from so many places. like a dozen plant species all *independently evolved* their caffeine production capabilities! https://t.co/Ox9eXScQPT

Oct 19, 2022 · 38 likes · 37,768 followers View post →
Exaptive
@exaptive · X

RT @SciUp: Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes https://t.co/FH8pNNNh3N https://t.co/UeI890…

Feb 23, 2019 · 1 share · 4,366 followers View post →
Scientific Update
@SciUp · X

Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes https://t.co/FH8pNNNh3N https://t.co/UeI8908zdO

Feb 23, 2019 · 3 likes · 1 share · 2,224 followers View post →