Many discussions delve into methodological aspects like biopsy results and brain activity interpretations, exemplified by references to fMRI findings and alternative explanations, which reflect a moderate to high level of engagement and recognition of the study's significance in ongoing debates about persistent post-finasteride symptoms.
AgreementNeither agree nor disagree
The discussions show mixed opinions, with some referencing the study design and interpretations, indicating neither full agreement nor disagreement.
InterestModerate interest
Participants display moderate interest, mainly focusing on methodological debates and possible implications.
EngagementModerate engagement
The conversations involve some depth, referencing related studies like fMRI results and letters to editors, suggesting thoughtful engagement.
ImpactModerate impact
The discussions highlight the importance of the topic, considering the clinical and biological implications of persistent symptoms after finasteride use.
Abstract in brief
The study compared men with persistent symptoms, men who used finasteride without symptoms, and men who never used it, finding that symptom-positive men had worse sexual function, depression, and cognitive complaints, but similar hormone levels and genetic markers compared to others.
Overall, the findings suggest that persistent symptoms are not caused by decreased androgen levels or peripheral androgen action, but may involve altered brain function linked to sexual arousal and mood regulation.]
@SimonBreidert @AVFIN_asso @kumarasri @CosimoMelcangi @gesbarreto @AmyPearlman1 @JoshpBerta @JuhanaSakari @JDaviesPhD See also Basaria et al. which included fMRI results.
https://t.co/S5hMDlKybB
There were differences btw study group & controls. In interpretation, authors likened this to depressive activation patterns, but this is debatable. (See letter to editor in right column by J. Santmann.)
Aug 8, 2022 · 3 likes · 2 shares · 816 followersView post →
FW
Finasteride Watch
@FinasterideInfo · X
If biopsies had been from penile tissue (where symptoms occur and there is a high density of SRD5A2), results might have been different.
Basaria, et al. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. J Clin Endocrinol Metab.
This video examines how intradermal botulinum toxin injections may help treat androgenetic alopecia. It discusses ways the toxin might improve blood flow or reduce muscle tension around hair follicles, potentially…
Men using 5-reductase inhibitors for androgenic alopecia may experience persistent sexual, psychological, and vascular side effects, including penile vascular abnormalities. This study highlights the potential long-term…
If biopsies had been from penile tissue (where symptoms occur and there is a high density of SRD5A2), results might have been different.
Basaria, et al. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. J Clin Endocrinol Metab.
Aug 8, 2022 · 2 shares · 1,430 followersView post →
FW
Finasteride Watch
@FinasterideInfo · X
@SimonBreidert @AVFIN_asso @kumarasri @CosimoMelcangi @gesbarreto @AmyPearlman1 @JoshpBerta @JuhanaSakari @JDaviesPhD See also Basaria et al. which included fMRI results.
https://t.co/S5hMDlKybB
There were differences btw study group & controls. In interpretation, authors likened this to depressive activation patterns, but this is debatable. (See letter to editor in right column by J. Santmann.)
Aug 8, 2022 · 3 likes · 2 shares · 816 followersView post →
FW
PS
PW
AF