PubHawk
Neurosci Bull December 2016 PMID 27696179

Long-Term Cognitive Improvement After Benfotiamine Administration in Patients with Alzheimer's Disease.

Xiaoli Pan, Zhichun Chen, Guoqiang Fei, Shumei Pan, Weiqi Bao, Shuhua Ren, Yihui Guan, Chunjiu Zhong

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Mentions

12
Peak: 2 in Sep 2025
across 5 sources since Sep 2020

Extended reach

14,827
potential audience

Total likes

166

Video views

4,541

Mentions per month

Sep 2020 – Sep 2025

Where it's discussed

  • X / Twitter3 posts
  • Facebook3 posts
  • YouTube2 videos
  • Reddit2 posts
  • News2 articles

AI synopsis

What people are saying

The discussions collectively convey positive reactions, with posts emphasizing that benfotiamine shows promise for Alzheimer's treatment, such as noting it is inexpensive and available over the counter. The tone and wording reflect curiosity and cautious optimism, with some users awaiting larger studies to confirm effects, indicating moderate engagement and perceived impact.

AgreementStrong agreement

Most discussions express support for the findings, highlighting benefits like cognitive improvements and accessibility.

InterestModerate interest

While some posts show curiosity about the treatment, overall interest remains moderate, focusing mainly on basic implications.

EngagementModerate engagement

Posts briefly mention mechanisms and potential, but do not deeply analyze the research details, indicating moderate engagement.

ImpactModerate impact

Comments suggest a belief that the research could influence treatment approaches, though this is not depicted as groundbreaking.

Abstract in brief

  • The study suggests that long-term use of benfotiamine, a supplement, can improve cognitive function in patients with mild to moderate Alzheimer's disease, even though it doesn't reduce brain amyloid deposits.
  • Over 18 months, patients taking benfotiamine showed an average rise of 3 points in their MMSE scores, indicating better cognitive abilities, and some showed increased brain activity on PET scans.
  • This research hints that benfotiamine might be a potential avenue for developing treatments that modify the course of Alzheimer's, addressing cognition directly rather than just symptoms.
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Top posts

Most liked on X and Bluesky
LynneN
@nightsong53 · X

https://t.co/cK0DDtBIZl improvements in Alzheimer's when Benfotiamine (fat soluble thiamine) is taken.

Sep 8, 2025 · 5 likes · 1 share · 7,056 followers View post →
LaurieEndicottThomas
@LaurieEThomas · X

@AllenFrancesMD Benfotiamine (a lipid-soluble form of thiamine) seems to be useful in treating Alzheimer's disease. It is also cheap and available over the counter. We are waiting for results from a larger study in the US. https://t.co/UmJtxD6kYV

Sep 24, 2020 · 1 like · 1,534 followers View post →

All mentions

Robert Olney
@boretrol · X

RT @nightsong53: https://t.co/cK0DDtBIZl improvements in Alzheimer's when Benfotiamine (fat soluble thiamine) is taken.

Sep 8, 2025 · 1 share · 1,693 followers View post →
LynneN
@nightsong53 · X

https://t.co/cK0DDtBIZl improvements in Alzheimer's when Benfotiamine (fat soluble thiamine) is taken.

Sep 8, 2025 · 5 likes · 1 share · 7,056 followers View post →
LaurieEndicottThomas
@LaurieEThomas · X

@AllenFrancesMD Benfotiamine (a lipid-soluble form of thiamine) seems to be useful in treating Alzheimer's disease. It is also cheap and available over the counter. We are waiting for results from a larger study in the US. https://t.co/UmJtxD6kYV

Sep 24, 2020 · 1 like · 1,534 followers View post →