January 2010 PMID 27713248

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity.

Alexander Panossian, Georg Wikman

Download social card

Mentions

286
Peak: 5 in Jul 2025
across 7 sources since Mar 2019

Extended reach

234,940
potential audience

Total likes

1,184

Video views

43,721

Mentions per month

Mar 2019 – Nov 2025

Where it's discussed

  • News227 articles
  • Facebook22 posts
  • Blogs15 articles
  • X / Twitter14 posts
  • YouTube3 videos
  • Reddit3 posts
  • Bluesky2 posts

AI synopsis

What people are saying

The overall tone suggests a balance between curiosity and skepticism, with posts referencing specific adaptogens and their effects, such as 'Ashwagandha and Rodiola Rosea', alongside mentions of the need for more research. This reflects moderate interest and engagement, driven by scientific details and cautious optimism about their potential benefits.

AgreementNeither agree nor disagree

Discussions acknowledge the potential benefits of adaptogens but also note limitations and the need for further research, reflecting cautious support rather than full agreement.

InterestModerate interest

Most posts express curiosity about adaptogens, mentioning specific substances like Ashwagandha and Rodiola, indicating moderate interest.

EngagementModerate engagement

Several contributions delve into molecular mechanisms and clinical implications, showing active engagement and deeper understanding.

ImpactNeutral impact

The discussions are primarily informational, with some indicating a general belief that adaptogens could influence stress management, but the overall societal impact remains uncertain.

Abstract in brief

  • Adaptogens are substances that help the body's resistance to stress and have various beneficial effects on the nervous system, such as neuroprotection, reducing fatigue, and improving mood and cognitive function.
  • Clinical and animal studies show that adaptogens increase mental capacity and reduce mental exhaustion, especially under stress, by supporting attention and reducing fatigue.
  • Research indicates that adaptogens work at the molecular level by regulating the body's stress response systems, including the hypothalamic-pituitary-adrenal axis and key molecules like HSP70, JNK1, FOXO, DAF16, cortisol, and nitric oxide.

Top posts

Most liked on X and Bluesky
La Jefita
@soylajefita · X

Ese artículo publicado por Panossian en MDPI es una revisión muy citada, pero incluso ahí reconocen que la mayoría de los estudios son preclínicos o con humanos en muestras muy pequeñas. https://t.co/UPA7gVAIcl 8/

Jul 19, 2025 · 53 likes · 4 shares · 78,727 followers View post →
Dr. Jay Wrigley
@hormonedietdoc · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity Ashwagandha and Rodiola Rosea would be at the top of the list. #stress #adaptogen #anxiety https://t.co/hej2QaSseu https://t.co/m9dwjfE8jk

Sep 7, 2021 · 18 likes · 5 shares · 106,332 followers View post →
Richard S
@Richard01173388 · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity https://t.co/Tr0bNDKZmX

Jan 16, 2025 · 1 like · 168 followers View post →
Cindy Bee
@SweetBNetwork · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. https://t.co/Nc8bocCL1R #SweetBNetwork #Business #health #holistichealth #holistic #Soulera #stress #stressfree

Mar 11, 2019 · 1 like · 104 followers View post →
Douglas Bailey
@dbail36 · X

RT @hormonedietdoc: Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protectiv…

Sep 8, 2021 · 5 shares · 1,459 followers View post →
MEET VACCINERESEARCH
@libertylives277 · X

Effects of #Adaptogens on the #Central #Nervous System and the Molecular Mechanisms Associated with Their #Stress—Protective Activity #pubmed #health https://t.co/v8mugh0Fjy

Oct 17, 2020 · 1,379 followers View post →

All mentions

Alberto Fatticcioni
@WildProton · X

RT @hormonedietdoc: Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protectiv…

Nov 12, 2025 · 5 shares · 1,277 followers View post →
Iulian Gudumac
@iuliangudumac.bsky.social · Bluesky

Sources: 637. Gudumac, I. (2025). Brainwave Alchemy. Neuro Spiritual Advantage R&D Team. 638. Panossian, A., Seo, E. J., & Efferth, T. (2020). Effects of adaptogens on the central nervous system. Pharmaceuticals, 13(8), 156. ...

Aug 7, 2025 View post →
Astrid Schilmann
@aschilmann · X

RT @soylajefita: Ese artículo publicado por Panossian en MDPI es una revisión muy citada, pero incluso ahí reconocen que la mayoría de los…

Jul 20, 2025 · 4 shares · 255 followers View post →
Wimen
@1a31551c566e43d · X

RT @soylajefita: Ese artículo publicado por Panossian en MDPI es una revisión muy citada, pero incluso ahí reconocen que la mayoría de los…

Jul 19, 2025 · 4 shares · 670 followers View post →
BereNice Ⓜ️©
@BereMCoronel · X

RT @soylajefita: Ese artículo publicado por Panossian en MDPI es una revisión muy citada, pero incluso ahí reconocen que la mayoría de los…

Jul 19, 2025 · 4 shares · 132 followers View post →
La Jefita
@soylajefita · X

Ese artículo publicado por Panossian en MDPI es una revisión muy citada, pero incluso ahí reconocen que la mayoría de los estudios son preclínicos o con humanos en muestras muy pequeñas. https://t.co/UPA7gVAIcl 8/

Jul 19, 2025 · 53 likes · 4 shares · 78,727 followers View post →
Furious Femme
@terrifiedintersex.bsky.social · Bluesky

Imagine: Your slow heart arrhythmia becomes a fast heart arrhythmia and the only medicine you can find to fix it is estradiol. “Guess I gotta be trans.” Then they find your right ovary. Oh shit. Now we redouble our efforts. Oh shit. There’s a uterus. OH SHIT! So you learn. And then share.

Jul 14, 2025 · 1 share View post →
Richard S
@Richard01173388 · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity https://t.co/Tr0bNDKZmX

Jan 16, 2025 · 1 like · 168 followers View post →
Erin Taylor
@ParaNerdox · X

A 2018 review found that adaptogens may help reduce symptoms of stress, anxiety, and depression. However, more research is needed to confirm these effects. #scientificresearch #mentalhealth 2/ https://t.co/vVv8IZ5Iyu

Mar 29, 2023 · 255 followers View post →
Douglas Bailey
@dbail36 · X

RT @hormonedietdoc: Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protectiv…

Sep 8, 2021 · 5 shares · 1,459 followers View post →
Tony McFadden
@tony_mcfadden65 · X

RT @hormonedietdoc: Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protectiv…

Sep 7, 2021 · 5 shares · 66 followers View post →
Rirende
@rirende · X

RT @hormonedietdoc: Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protectiv…

Sep 7, 2021 · 5 shares · 104 followers View post →
Dr. Jay Wrigley
@hormonedietdoc · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity Ashwagandha and Rodiola Rosea would be at the top of the list. #stress #adaptogen #anxiety https://t.co/hej2QaSseu https://t.co/m9dwjfE8jk

Sep 7, 2021 · 18 likes · 5 shares · 106,332 followers View post →
MEET VACCINERESEARCH
@libertylives277 · X

Effects of #Adaptogens on the #Central #Nervous System and the Molecular Mechanisms Associated with Their #Stress—Protective Activity #pubmed #health https://t.co/v8mugh0Fjy

Oct 17, 2020 · 1,379 followers View post →
Heather Constance
@heathencc · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity More random stuff I’m reading today. https://t.co/8gxSdy3pLG

Aug 8, 2020 · 208 followers View post →
Cindy Bee
@SweetBNetwork · X

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. https://t.co/Nc8bocCL1R #SweetBNetwork #Business #health #holistichealth #holistic #Soulera #stress #stressfree

Mar 11, 2019 · 1 like · 104 followers View post →