Ann N Y Acad Sci March 2017 PMID 27750377

Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus.

Joshua J Joseph, Sherita H Golden

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Mentions

16
Peak: 2 in Aug 2024
across 4 sources since Jul 2019

Extended reach

348,975
potential audience

Total likes

3,949

Video views

348,171

Mentions per month

Jul 2019 – Aug 2025

Where it's discussed

  • News8 articles
  • X / Twitter3 posts
  • Facebook3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect both support and curiosity about the biological mechanisms linking stress to health issues, such as mentions of the HPA axis and cortisol's role in insulin resistance, with tone indicating a recognition of the publication's importance but also some focus on practical management tips.

AgreementModerate agreement

Most discussions acknowledge the connection between cortisol dysregulation and metabolic or cardiovascular risks, showing general support for the publication's conclusions.

InterestHigh interest

Participants show high curiosity about managing cortisol through lifestyle changes and its biological implications, indicating notable interest.

EngagementModerate engagement

Comments reflect some depth, with references to specific systems like the HPA axis and its role in stress and metabolism, demonstrating meaningful engagement.

ImpactModerate impact

The discussions suggest awareness of the clinical significance, especially in relation to cardiovascular health and insulin resistance, pointing to moderate impact.

Abstract in brief

  • The article discusses the complex relationship between stress, depression, and type 2 diabetes, highlighting that while depression is clearly linked to increased risk of diabetes, the role of stress is less certain due to varying research methods.
  • It explains that the body's stress response involves systems like the HPA axis, autonomic nervous system, and immune system, with depression often leading to changes in cortisol levels, such as a flattened diurnal cortisol curve, which is also associated with insulin resistance and diabetes.
  • The main focus is on how dysregulation of the HPA axis, which manages stress responses, may serve as a biological connection between stress, depression, and the development of type 2 diabetes.]

Top posts

Most liked on X and Bluesky
Nikos Noulezas
@NikosNoulezas · X

@coookwithchris HPA-axis dysfunction leads to abnormal cortisol secretion, followed by insulin resistance/type 2 diabetes. A greatly increased risk of CVD https://t.co/b5yZKEmF6K

Feb 2, 2022 · 704 followers View post →
AhmadHesam
@AhmadHe88222021 · X

Cortisol senken: Tipps zu Ernährung und Übungen gegen Stress | Dr. Julia... https://t.co/BmPrGHVwCo

Aug 29, 2024 · 95 followers View post →

All mentions

AhmadHesam
@AhmadHe88222021 · X

Cortisol senken: Tipps zu Ernährung und Übungen gegen Stress | Dr. Julia... https://t.co/BmPrGHVwCo

Aug 29, 2024 · 95 followers View post →
Nikos Noulezas
@NikosNoulezas · X

@coookwithchris HPA-axis dysfunction leads to abnormal cortisol secretion, followed by insulin resistance/type 2 diabetes. A greatly increased risk of CVD https://t.co/b5yZKEmF6K

Feb 2, 2022 · 704 followers View post →
Fazl e Haq
@fazalovais · X

Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus https://t.co/wzb9TmyuCY

Jul 23, 2019 · 6 followers View post →