@realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial.
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Jan 2019 – Nov 2025Where it's discussed
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News218 articles
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X / Twitter84 posts
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Facebook42 posts
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YouTube3 videos
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Bluesky1 posts
AI synopsis
What people are saying
The overall tone reflects strong agreement and enthusiasm, with posts citing specific research studies like Frye et al.'s clinical trial and mentioning biological explanations such as folate receptor autoantibodies. The detailed references and discussion of potential treatment implications reveal active engagement and recognition of the research's importance for future therapies.
Most discussions strongly support the findings, using affirming phrases like 'really interesting,' 'promising,' and references to multiple studies, indicating widespread acceptance.
Posts show high interest, with many users mentioning the potential benefits, linking to studies, and discussing biological mechanisms, displaying active curiosity.
Several users cite detailed research, such as Frye et al.'s 2016 trial and mention of autoantibodies, demonstrating deep engagement and specific knowledge integration.
Multiple posts emphasize the significance of the research for treatment options, policy implications, and parental considerations, suggesting a high perceived impact.
Abstract in brief
- The study found that high-dose folinic acid significantly improved verbal communication in children with autism and language impairment, especially in those with FRAA positivity, indicating a potentially more effective response in this subgroup.
- Improvements were also observed in other behavioral measures, such as adaptive behavior and autism symptoms, with no increase in adverse effects, suggesting that folinic acid is generally safe and beneficial.
- The results support the idea that folinic acid could be a promising treatment to enhance communication in children with ASD, particularly for those with specific autoantibody profiles, though larger studies are needed for confirmation.]
Top posts
Most liked on X and Bluesky@dr_andrealove If only you were a real doctor https://t.co/77CrIGQOri https://t.co/77CrIGQOri
@Kozmocostello @zerohedge Here’s a few studies for you look through. Let me know when you’re done and I’ll send over some more. This is wonderful news for children and adults with autism. Who gets upset about this??! Jesus Folinic acid improves verbal communication in children with autism and language
Parents say son with autism was nonverbal until trying an off-label drug that treats chemo side effects https://t.co/aQP1QMqzzA Folinic acid front-and-centre. Here's some science: https://t.co/D8SogVyhad & some more: https://t.co/u7QDQ6KZlr There's your autism research targets.
14/ Frye RE, et al. Mol Psychiatry 2018. RCT: folinic acid improved language in FRAA-positive autistic children. https://t.co/GAuzN9T46O
@Juliesnark1731 Leucovorin is B9 folinic acid. Read up
All mentions
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Robots and Autism Spectrum Disorders: An Overview
This video introduces a series exploring literature on the intersection of autism spectrum disorders (ASD) and robotics to enhance communication skills. It covers key definitions, the role of social robots, and the need…
Understanding Tylenol's Link to Autism and Nutritional Support
In this episode of The Nourishing Autism Podcast, Brittyn discusses claims that Tylenol may cause autism, emphasizing that it's not the full story. The episode explores glutathione's role as a master antioxidant…
https://t.co/pCO3KiK6fy
@RealDrJaneRuby @US_FDA Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies
RT @MeeshFL: @thegarybrecka Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with auti…
@zbingeldac @Inversionism https://t.co/OWrWuLanJh
RT @MeeshFL: @stopvaccinating Vitamin B9 folinic acid (Leucovorin) Folinic acid improves verbal communication in children with autism and…
@IzabelTheodora @Inversionism Dr. Richard Frye is a good resource on this. Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial: https://t.co/i8Ynu3bHHN
@howelcb @Rightanglenews They have, and it’s very promising. 71% of people with ASD symptoms have a problem where antibodies prevent folate from getting to the brain. This active forms of folate bypasses that and is able to pass the blood brain barrier. https://t.co/J8wIxsSkMV https://t.co/qexPNK4fpl
@LTrain5407 @disillusioned0x @Rightanglenews Just in case grok doesn't get to it: Frye et al. (2016, USA) RCT: https://t.co/hZJeRfk0b1 Ramaekers et al. (2020, France) EFFET Trial: https://t.co/bvI2ROcxqE Ghaleiha et al. (2020, Iran): https://t.co/xXr3gzJEiM Panda et al. (2024, India): https://t.co/Bmvu45gmvY Wang et
@disillusioned0x @Rightanglenews Frye et al. (2016, USA) RCT: https://t.co/hZJeRfk0b1 Ramaekers et al. (2020, France) EFFET Trial: https://t.co/bvI2ROcxqE Ghaleiha et al. (2020, Iran): https://t.co/xXr3gzJEiM Panda et al. (2024, India): https://t.co/Bmvu45gmvY Wang et al. (2025, China):
@SwiftKardia @RepMTG @SecKennedy Orange man bad!!!! Meanwhile in science world: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
@tajhokenf @RepMTG @SecKennedy Orange man bad!!!! Meanwhile in science world: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
@Patti78746960 @RepMTG @SecKennedy Orange man bad!!!! Meanwhile in science world: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
@ICONemily1999 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@UniverseCommon @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@soughtgod @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp2pAZ Cerebral Folate Deficiency, Folate
@gypsyluc @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@GatorNature @RepMTG @SecKennedy Trust the science bro: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp2pAZ Cerebral
@Terrytoo69 @RepMTG @SecKennedy Trust the science bro: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral
@The38Super @RepMTG @SecKennedy It did for many. Not all but many. Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr
@AmandaE73788354 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@wiguy45 @RepMTG @SecKennedy Ok: Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency,
RT @ftxclone: @AllahJesusXenu @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid…
@LindaCo13916874 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@dayquiljones2 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@NickK51654981 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@BurtMaclin_FBI @RepMTG @mtgreenee @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@1776x_com @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@AllahJesusXenu @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@JosephMothers2 @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@MikeRunsMiles @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
@jimstewartson @RepMTG @SecKennedy Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr Cerebral Folate Deficiency, Folate
RT @ultimape: "Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placeb…
@tazer_blazer @RepMTG @SecKennedy You an autism researcher? Or you just assuming it doesn’t make sense? Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind
@ChilloutVille @RepMTG @SecKennedy MTG is whacky but so are you. Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/J97ERp1RLr
@MargaretSusanM6 @KupoPewPew @RepMTG @SecKennedy You are playing politics with your child’s wellbeing. Sad. Studies about folinic acid: Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
@DwanePorter @RepMTG @SecKennedy How about there are studies!
@thegarybrecka Vitamin B9 folinic acid (Leucovorin) studies Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies
#AutismAwareness Leucovorin Calcium. Folinic acid improves verbal communication in children with autism and language impairment. https://t.co/Gns0tkAVXq https://t.co/AZGQI2NOZV
More concerns: 2018 paper: 48 subjects, positive results pubmed.ncbi.nlm.nih.gov/27752075 Clinical trial: 0 subjects, terminated by FDA and sponsor for PI non-compliance. www.clinicaltrials.gov/study/NCT016... Yes, this is the same trial. Scroll down to Publications to confirm.
@stopvaccinating Vitamin B9 folinic acid (Leucovorin) Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and
@MAHA_Action Folinic acid Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid)
@Dtownfanman @TheChiefNerd @MartyMakary Folinic acid Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid)
@NYPoliticalMom https://t.co/STVs2PABJg Here’s the link if you’re interested. I think they’re jumping the gun but I hope this will stop desperate parents from ordering it online because their peds won’t prescribe it or give any kind of guidance.
@HHSGov @DrOzCMS @US_FDA @NIH Folinic acid Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid)
@maideninthewood @C2665Michelle @Denver4VA https://t.co/d6m0GUD7UK
RT @MeeshFL: @realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized doubl…
RT @MeeshFL: @realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized doubl…
@Mollyploofkins Study from 2016 Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/lUIPwLAyMv
RT @MeeshFL: @realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized doubl…
RT @MeeshFL: @realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized doubl…
@stopvaccinating I just read that study. It’s really interesting. I don’t think I saved it but I’ll look. Here’s some other information Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
@dr_andrealove If only you were a real doctor https://t.co/77CrIGQOri https://t.co/77CrIGQOri
@Craig_A_Spencer Yes folinic acid (leucovorin) can help improve autism. I bet they would find 75% of these children have MTHFR. Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial.
RT @MeeshFL: @realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized doubl…
@Juliesnark1731 Leucovorin is B9 folinic acid. Read up
@realdefender45 Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in
@politicalFF @realdefender45 Here’s some studies and other reading material ♥️ best of luck to your little boy! I have two boys, 5 & 8 ☺️ Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/xR2njEzhfk
@Kozmocostello @zerohedge Here’s a few studies for you look through. Let me know when you’re done and I’ll send over some more. This is wonderful news for children and adults with autism. Who gets upset about this??! Jesus Folinic acid improves verbal communication in children with autism and language
@tokintroll @EricLDaugh Here you go https://t.co/eTrxDCuvqF https://t.co/YyfA81Qk8z https://t.co/E0iNb1vLsd https://t.co/w5gyCRQoBY
@A86Spez @zerohedge @RobertKennedyJr https://t.co/NP3tKmyluZ https://t.co/cU96NML8zc https://t.co/pWjoUhMFT0 https://t.co/C9kyLd66mR https://t.co/ftDZP8xLlw I put the links into grok and have it and have it summarize it for me. These are just a few of many particles on PubMed
@cuntycatlady @simonmaechling This one has an additional 38 https://t.co/6rmbODGoP1
RT @kinziefur: @EricLDaugh For 9 yrs they've known that folinic acid can help autistic kids. This is the first time I've heard of it. Fol…
@EricLDaugh For 9 yrs they've known that folinic acid can help autistic kids. This is the first time I've heard of it. Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/eSWQo8MnOB
RT @IntegralAnswers: 14/ Frye RE, et al. Mol Psychiatry 2018. RCT: folinic acid improved language in FRAA-positive autistic children. htt…
14/ Frye RE, et al. Mol Psychiatry 2018. RCT: folinic acid improved language in FRAA-positive autistic children. https://t.co/GAuzN9T46O
@theliverdr What about this https://t.co/Jd05MX6AYs
@Autism @MailOnline https://t.co/AfMEwnS8tA
Parents say son with autism was nonverbal until trying an off-label drug that treats chemo side effects https://t.co/I0eb1OCy9P… Folinic acid front-and-centre. Here's some science: https://t.co/xi5h1JqiBU & some more: https://t.co/EGf0PDrUKl https://t.co/zN5zSlwGPJ
Parents say son with autism was nonverbal until trying an off-label drug that treats chemo side effects https://t.co/aQP1QMqzzA Folinic acid front-and-centre. Here's some science: https://t.co/D8SogVyhad & some more: https://t.co/u7QDQ6KZlr There's your autism research targets.
@BeAVoice4Autism Another tough question. I'd like to believe there was some common mechanism, something that 'all roads lead to', but the sheer complexity of the brain, central nervous system and other biology makes this look unlikely. There's clues: https://t.co/u7QDQ6LxaZ however...
https://t.co/c0E3p0w4Aq
@drdenwalker Yes thankfully I did this a decade ago. Also “enriched flour” has folic acid in it which I avoid. Also very important for those with autism and consider folinic acid instead: https://t.co/JoktL5kDL1 https://t.co/2Z0nc5Gemw
@SethUnderwood56 Possibly. The trials on folinic acid in the context of autism have tended to include this group e.g. https://t.co/HiK1Zuq8SV
Folinic acid improves verbal communication in children with autism and language impairment: https://t.co/4C9HZBc9ri
"Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial" https://t.co/s7jUPiqQ9p Citation 69? about mTOR. https://t.co/yjzhdfWijD Nice. https://t.co/gPfBFAe9r7
@faustosette @Sean_Great_C137 @Babygravy9 no… folonic acid. https://t.co/OdyOiFCvON
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/TGoBPadsNn
Speech Development Across Subgroups of Autistic Children: A Longitudinal Study https://t.co/EC2QF9C2Y2 Various trajectories. Possible biological intervention for some e.g. https://t.co/HiK1Zuq8SV
@MxOolong Indeed. But where there is an identified biological issue (e.g. folate autoantibodies & use of folinic acid), denial of medical action is akin to acceptance of health inequality. And if it affects presentation e.g. https://t.co/HiK1Zuq8SV
RT @PaulWhiteleyPhD: New U.S. autism guidelines call for early treatment https://t.co/YOjEuCm8Lg Further to last tweet. Note that 'treatmen…
New U.S. autism guidelines call for early treatment https://t.co/YOjEuCm8Lg Further to last tweet. Note that 'treatment' does not just solely include psychological/behavioural. For example: https://t.co/7A3jiKyfYK
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/rBKkY6p8oK #Autism #Science #Health #FolicAcid #Methylation #MTHFR #Supplements #Diet #Nutrition
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial https://t.co/iIjfwrE1Ev
Helped most with folate receptor antibody positive patients: Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial. - PubMed - NCBI https://t.co/PzbIT6sOVa
RT @IliadFRATtest: Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind pl…
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