Curr Biol November 2016 PMID 27773569

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers.

Francisca Leal, Martin J Cohn

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Mentions

26
Peak: 4 in Apr 2022
across 4 sources since Nov 2016

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Nov 2016 – Aug 2025

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AI synopsis

What people are saying

The discussions reflect a balanced curiosity and acknowledgment of the article's importance, with users mentioning genetic elements like Sonic hedgehog and HOXD enhancers, and describing the study as revealing crucial insights into the genetic mechanisms behind limb loss and re-emergence in snakes. The tone and focus on specific genes and evolutionary processes suggest a meaningful engagement with the scientific content and its broader impact.

AgreementModerate agreement

Most discussions acknowledge the scientific findings about genetic factors influencing limb development in snakes, with some expressing surprise or approval.

InterestModerate interest

Posts demonstrate a moderate level of curiosity, with users showing interest in the genetic and evolutionary aspects of the study.

EngagementModerate engagement

Participants reference specific genes like Sonic hedgehog and HOXD enhancers, suggesting deeper engagement with the research details.

ImpactModerate impact

Several discussions highlight the significance of the research, indicating an appreciation for its implications in understanding evolutionary development and future scientific advancements.

Abstract in brief

  • The study explains how snakes lost their limbs through mutations affecting the Sonic hedgehog (SHH) gene enhancer, leading to weakened limb development, but some limb structures persisted in their ancestors.
  • Despite limb loss, certain genetic elements like HOXD enhancers remain conserved in snakes, allowing the potential reemergence of hindlimb structures during evolution.
  • The findings suggest that the loss and occasional reappearance of limbs in snakes involved modifications in specific genetic regulatory regions rather than complete de novo creation or total loss of limb development capabilities.]

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高遠 頼@生命科学VTuber(たかとー らい) 定期科学ニュース配信(日)
@takatoh_life · X

ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 8 likes · 4 shares · 14,371 followers View post →
Stephen Riffle, Ph.D.
@EyaSpectre · X

@JackDAshby https://t.co/ZHYntDzwsL

Oct 21, 2021 · 1 like · 1,206 followers View post →
きゃきらん
@kyakirun · X

RT @takatoh_life: ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 4 shares · 1,245 followers View post →
Maik Damm
@DammMaik · X

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers doi: 10.1016/j.cub.2016.09.020 Progressive Loss of Function in a Limb Enhancer During Snake Evolution doi: 10.1016/j.cell.2016.09.028

Jun 5, 2020 · 1,177 followers View post →
くろのーげん
@n0gen · X

RT @takatoh_life: ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 4 shares · 803 followers View post →
りん☆ちゃん
@Sarrink · X

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers: Current Biology - https://t.co/Doft2mUbjv ตั้งชื่อเหี้ยไรเนี่ย 555555555

Dec 2, 2019 · 592 followers View post →

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アームストロング=力丸 POWER 強(つよし)
@GachiMuchiPower · X

RT @takatoh_life: ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 4 shares · 128 followers View post →
くろのーげん
@n0gen · X

RT @takatoh_life: ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 4 shares · 803 followers View post →
きゃきらん
@kyakirun · X

RT @takatoh_life: ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 4 shares · 1,245 followers View post →
高遠 頼@生命科学VTuber(たかとー らい) 定期科学ニュース配信(日)
@takatoh_life · X

ヘビが脚を失ったメカニズムとかはソニックヘッジホッグ遺伝子の欠損が原因らしいです

Apr 22, 2022 · 8 likes · 4 shares · 14,371 followers View post →
Stephen Riffle, Ph.D.
@EyaSpectre · X

@JackDAshby https://t.co/ZHYntDzwsL

Oct 21, 2021 · 1 like · 1,206 followers View post →
trish!
@witchmagica · X

in fact, according to another article, it may be easier to turn it on in theory because the rudimentary bones needed for limbs still exist in some species of snakes where presence of limbs is not entirely eliminated https://t.co/I7OWi6wVU0

Dec 11, 2020 · 175 followers View post →
Maik Damm
@DammMaik · X

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers doi: 10.1016/j.cub.2016.09.020 Progressive Loss of Function in a Limb Enhancer During Snake Evolution doi: 10.1016/j.cell.2016.09.028

Jun 5, 2020 · 1,177 followers View post →
りん☆ちゃん
@Sarrink · X

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers: Current Biology - https://t.co/Doft2mUbjv ตั้งชื่อเหี้ยไรเนี่ย 555555555

Dec 2, 2019 · 592 followers View post →
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