ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に摂取するように増加するとのこと。 https://t.co/mrVTaGRfGc
How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake.
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May 2020 – Sep 2025Where it's discussed
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AI synopsis
What people are saying
The discussions highlight critical insights from the article, such as the increase in appetite by approximately 100 kcal for every kilogram lost, with several participants emphasizing phrases like 'appetite counteracts weight loss' and 'a major challenge in maintaining weight'. The tone creates a sense of urgency about addressing long-term weight management, particularly illustrated by claims about the challenges of sustaining weight loss without altering behavioral patterns, pointing towards the substantial impact of appetite regulation on weight control.
Most discussions express a consensus with the publication's findings on appetite and weight loss.
The conversations showcase a high level of curiosity and relevance regarding how appetite influences weight management.
Many participants delve into specifics regarding methodology and implications, reflecting a profound consideration of the research.
Users generally perceive the findings to hold significant implications for understanding weight loss challenges.
Abstract in brief
- The study aimed to measure how appetite affects weight loss by manipulating energy balance in a group of 153 patients over 52 weeks while they were unaware of their energy deficit.
- It was found that for each kilogram of weight lost, appetite increased, leading individuals to consume about 100 extra calories per day, which is significantly more than the adjustments in energy expenditure.
- The results suggest that appetite has a stronger influence on weight regain than previously thought, making it challenging to maintain long-term weight loss.
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Most liked on X and Blueskyダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、エネルギー消費量は30kcal減少する可能性があるとのこと。 https://t.co/mrVTaH8iIc
For each kg weight loss appetite
Hypothesis: Sustained physical activity attenuates the feedback signal controlling appetite bc reduced RMR only partially compensates for increased activity expenditure & therefore allows for greater energy intake at a given level of sustained weight loss. https://t.co/chh0IMkBsV
For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
The model of energy intake assumed a constant effect of the calorie restriction intervention, but this was superimposed on the physiological system controlling appetite in proportion to lost weight resulting in increased intake until the weight plateau. https://t.co/chh0IMCKH3
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@KevinH_PhD I just read your study: 'How strongly does appetite counter weight loss? Quantification of the feedback control of human energy intake' Is there somewhere more to learn about how a person's 'baseline' 'energy intake' comes to be? I assume it's mostly genetic?
RT @UKLowCarb: @DikemanDave @raphaels7 I heard Kevin Hall on the radio saying that over 1 year a "deficit" is reduced to 20% of its intende…
@DikemanDave @raphaels7 I heard Kevin Hall on the radio saying that over 1 year a "deficit" is reduced to 20% of its intended value by appetite increase. https://t.co/RHkpfHZBbH https://t.co/6g5ThlsIGZ
RT @KevinH_PhD: For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
RT @KevinH_PhD: For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
RT @KevinH_PhD: For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
For details see the following papers: pubmed.ncbi.nlm.nih.gov/27804272/ pubmed.ncbi.nlm.nih.gov/29896621/ pubmed.ncbi.nlm.nih.gov/38644683/
RT @KevinH_PhD: For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
For details see the following papers: https://t.co/chh0IMCKH3 https://t.co/VV0ZWXZjLI https://t.co/oLyKjaJyF5
4) How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake (2016) onlinelibrary.wiley.com/doi/full/10....
@AreProjectors I don't know whether that model is correct. An alternative is that the strength of the homeostatic reaction is proportional to distance from setpoint. I think most people will have a homeostatic reaction from less wt loss than that, e.g. in this trial. https://t.co/135vb1xBuq
@DrEenfeldt That's one hypothesis, called the "settling point" hypothesis. I don't think it can explain the findings of this study though, and others reporting similar things. https://t.co/GoyTSCN7w0
@DrEenfeldt This study by @KevinH_PhD also provides direct evidence for a homeostatic reaction to weight loss https://t.co/GoyTSCN7w0
RT @allurionceo: For every kilo of weight you lose, appetite increases by 100 kcal / day. This is why without behavior change, weight maint…
For every kilo of weight you lose, appetite increases by 100 kcal / day. This is why without behavior change, weight maintenance is nearly impossible. This is why we do what we do at $ALUR. https://t.co/LfpRQqLK41
RT @DanielBerglind: For each kg weight loss appetite
RT @DanielBerglind: For each kg weight loss appetite
RT @DanielBerglind: For each kg weight loss appetite
RT @takumasa39: 論文リンク https://t.co/mrVTaGRfGc
RT @takumasa39: 論文リンク https://t.co/mrVTaGRfGc
RT @DanielBerglind: For each kg weight loss appetite
論文リンク https://t.co/mrVTaGRfGc
RT @DanielBerglind: For each kg weight loss appetite
RT @DanielBerglind: For each kg weight loss appetite
For each kg weight loss appetite
RT @sguyenet: @rustneversleepz I think this is the seminal paper on this. You might find it informative https://t.co/135vb1xBuq
@rustneversleepz I think this is the seminal paper on this. You might find it informative https://t.co/135vb1xBuq
Ref: Polidori D, et al. How Strongly Does Appetite Counter Weight Loss? Quantification of the Feedback Control of Human Energy Intake. Obesity (Silver Spring). 2016 Nov;24(11):2289-2295.
RT @KevinH_PhD: Hypothesis: Sustained physical activity attenuates the feedback signal controlling appetite bc reduced RMR only partially c…
@exfatloss There are many well-documented examples of homeostatic regulation that can't be explained by the settling point model. Here are two https://t.co/GoyTSCNFly https://t.co/LqGotujGIx
Fuente
@RodolfoJGalindo I got this statistic from this Obesity review article: https://t.co/XUvtNTA9zP Original work was from: https://t.co/6sOkEMB93Y
RT @KevinH_PhD: The model of energy intake assumed a constant effect of the calorie restriction intervention, but this was superimposed on…
The model of energy intake assumed a constant effect of the calorie restriction intervention, but this was superimposed on the physiological system controlling appetite in proportion to lost weight resulting in increased intake until the weight plateau. https://t.co/chh0IMCKH3
Evidence indicates that appetite increases 100kcal for every 1kg of weight loss and energy expenditure may drop 15% for a 10% decrease in body weight. So what does this look like in practice! Increasing #satiety has to be the answer https://t.co/pTVSXJzo35 https://t.co/pUQYTzXuMT https://t.co/8gmbZ75o8F
9) ¿Hasta qué punto contrarresta el apetito la pérdida de peso? Cuantificación del control de retroalimentación de la ingesta energética humana https://t.co/teQF5gVfFx #ActualizateconFINUT
RT @KevinH_PhD: @AbdTahrani @dr_kevinlee @drteohsh @BevTchangMD @ObesityAction @SCOPEObesity @OMAsocial @WorldObesity @AaronKelly_PhD @Obes…
@AbdTahrani @dr_kevinlee @drteohsh @BevTchangMD @ObesityAction @SCOPEObesity @OMAsocial @WorldObesity @AaronKelly_PhD @ObesitySociety Right, so maybe it’s not surprising that people report no significant changes in appetite because they are eating more calories?
@AbdTahrani I’m sure you are aware of Polidori et al., 2016, which suggests the appetite change is the most relevant adaptation leading to weight recurrence. https://t.co/etoQob7Bn1
場合はもう少しゆるやかな数値になる可能性大 https://t.co/cF08gfO6eg #自分用メモ
RT @NutritionXenia: fuente: https://t.co/3qUrGDmgI5
RT @NutritionXenia: fuente: https://t.co/3qUrGDmgI5
fuente: https://t.co/3qUrGDmgI5
RT @MichaelAlbertMD: @DavidMacklinMD @DrNadolsky @ClemmensenC @JohnSpeakman4 Are all these individuals near LIP? https://t.co/e4mZDFfSK7 ht…
@DavidMacklinMD @DrNadolsky @ClemmensenC @JohnSpeakman4 Are all these individuals near LIP? https://t.co/e4mZDFfSK7 https://t.co/06TUvOy4Sf
RT @KevinH_PhD: In other words, the authors assumed that the estimated reduction in calorie intake due to their intervention would persist…
RT @KevinH_PhD: In other words, the authors assumed that the estimated reduction in calorie intake due to their intervention would persist…
RT @KevinH_PhD: In other words, the authors assumed that the estimated reduction in calorie intake due to their intervention would persist…
In other words, the authors assumed that the estimated reduction in calorie intake due to their intervention would persist at a constant level for 12 months. This neglects the likely increase in appetite that occurs as weight is lost: https://t.co/chh0IMCcRv
RT @dwrowland: Weight control and management can be challenging and feedback control could make it even more difficult: "weight loss leads…
Weight control and management can be challenging and feedback control could make it even more difficult: "weight loss leads to a proportional increase in appetite resulting in eating above baseline by ∼100 kcal/day per kilogram of lost weight" https://t.co/qAz9nQkR7g
@AlexJLeaf I think it's probably not correct that people with obesity are simply floating upward, independently of homeostasis. The reason is that the setpoint (or whatever) appears to rise with them, opposing even modest wt loss. https://t.co/GoyTSD4Iny
RT @KevinH_PhD: @RossWollen @ScepticalDoctor @KetoCarnivore This kind of exponential pattern of energy intake is what would be predicted fo…
Probably not. We have since quantified how long-term weight loss results in increased appetite and energy intake over time, even when the intervention has a constant effect. This explains why SGLT2i doesn't result in substantial long-term weight losses. https://t.co/chh0IMCKH3
RT @KevinH_PhD: @angryhacademic Unfortunately, the existing NIH body weight planner doesn’t account for the changes in appetite that occurs…
@angryhacademic Unfortunately, the existing NIH body weight planner doesn’t account for the changes in appetite that occurs with weight loss. See below: https://t.co/chh0IMCcRv https://t.co/VV0ZWXYLWa
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
RT @takumasa39: ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に…
ダイエットしても多くの人がリバウンドしてしまいます。 https://t.co/QNZJKcyhYS これは失った脂肪を取り戻そうとする恒常性によるものであり、Obesityの報告では、体重を1kg減らすと、食欲は1日あたり100kcal余分に摂取するように増加するとのこと。 https://t.co/mrVTaGRfGc
RT @KevinH_PhD: Hypothesis: Sustained physical activity attenuates the feedback signal controlling appetite bc reduced RMR only partially c…
Hypothesis: Sustained physical activity attenuates the feedback signal controlling appetite bc reduced RMR only partially compensates for increased activity expenditure & therefore allows for greater energy intake at a given level of sustained weight loss. https://t.co/chh0IMkBsV
RT @doctorarrietam: Parte importante del problema es que la atención se enfoca en el corto plazo y no en el mantenimiento. Cambio tu atenci…
Parte importante del problema es que la atención se enfoca en el corto plazo y no en el mantenimiento. Cambio tu atención a lo importante y verás como cambia tu vida (3/3). https://t.co/lasUdMjrcU
RT @KevinH_PhD: @AbdTahrani @Mpmok @FionaQuigs Her appetite conclusion is based primarily on subjective measures & lack of significant corr…
@AbdTahrani @Mpmok @FionaQuigs Her appetite conclusion is based primarily on subjective measures & lack of significant correlation between ghrelin changes after weight loss and subsequent weight regain. IMO, this doesn't justify the conclusion. Rather, see: https://t.co/VXrrgFqt0U https://t.co/chh0IMkBsV
RT @whsource: Let's look at some studies. One of my favorites was conducted by @KevinH_PhD group. Negative energy balance was *covertly*…
Let's look at some studies. One of my favorites was conducted by @KevinH_PhD group. Negative energy balance was *covertly* induced in humans and energy intake and expenditure responses were estimated. https://t.co/GoyTSD4Iny
Excellent thread. Reading Hall's paper on energy imbalance induced by SGLT2 inhibition is an eye-opener, and a magnificent proof of concept. https://t.co/YGd9yhQ35x https://t.co/LjSPXgs8BR
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
RT @takumasa39: ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、…
ダイエットをすると脳の視床下部は食欲を増やし、エネルギー消費量を減らします。これがリバウンドのメカニズムとされています。 https://t.co/QNZJKcPl0S Obesityの報告では、体重が1kg減ると食欲は1日100kcal増え、エネルギー消費量は30kcal減少する可能性があるとのこと。 https://t.co/mrVTaH8iIc
@LuaWilkinson @DaveHPT @FoodFirst_Ty https://t.co/3bGxXNFLQV
@FusionProgGuy The following paper describes how we estimated that appetite increases by ~95kcal/d above baseline for every kg of lost weight. https://t.co/chh0IMCcRv
@erik_arnesen I'm pretty sure the overall hypothesis advanced by that author is wrong though-- see this study by Kevin Hall, which is a pretty clean test of the hypothesis based on data from a double blind RCT. https://t.co/135vb1g05Q
RT @whsource: This paper by @KevinH_PhD is one of the most informative I've ever read about what happens when people lose weight. https:/…
@astridwilde1 @lisaquestions She doesn’t think internalised racism and fat phobia is a thing https://t.co/ZX0PLJ2jzx
@Benteov Appetitt øker også proporsjonalt med vekttap: https://t.co/WLr8CIIYCk
@ben_r_hoffman @jimrandomh It was not designed to study subjects as they "reach their new equilibria" which takes many months due to the operation of parallel negative feedback control circuits regulating expenditure and iintake: https://t.co/mkRSi4ztO3