Cell Mol Neurobiol August 2017 PMID 27832395

mitoLUHMES: An Engineered Neuronal Cell Line for the Analysis of the Motility of Mitochondria.

Tomasz M Stępkowski, Sylwia Męczyńska-Wielgosz, Marcin Kruszewski

Mentions

4
Peak: 3 in Sep 2016
across 2 sources since Sep 2016

Extended reach

23,745
potential audience

Total likes

84

Video views

14,640

Mentions per month

Sep 2016 – Dec 2022

Where it's discussed

  • YouTube3 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

Discussions typically praise the article for introducing mitoLUHMES as a promising tool to study mitochondrial dynamics, with posts highlighting phrases like 'valuable model' and 'real-time visualization.' The tone is generally positive and interested, especially in how this model could revolutionize research into neurodegenerative diseases, reflecting a balanced view of its potential and its current significance.

AgreementModerate agreement

Most discussions express support or approval for the research, highlighting its potential benefits, especially in neurodegenerative studies.

InterestHigh interest

Many posts show high curiosity, often mentioning the innovative techniques and the importance of mitochondrial visualization in neurons.

EngagementModerate engagement

Several comments delve into methodological details or implications, indicating active engagement with the research's significance.

ImpactModerate impact

Participants recognize the model's potential to advance understanding of mitochondrial behavior, suggesting moderate recognition of its impact on neurobiology.

Abstract in brief

  • The study introduces mitoLUHMES, a modified neuronal cell line that expresses fluorescent proteins to allow real-time visualization of mitochondrial movement and behavior, which is useful for studying neurodegenerative diseases.
  • Researchers demonstrated that mitoLUHMES can differentiate into neurons and be used to observe processes like mitochondrial fission, fusion, and movement reversal, providing detailed insights into mitochondrial dynamics.
  • Treatment with neurotoxins caused significant changes in mitochondrial morphology and dynamics, highlighting mitoLUHMES as a valuable model system for investigating mitochondrial function and dysfunction in neurobiology research.

Top posts

Most liked on X and Bluesky
Nicole Laurent, LMHC
@KetoCounselor · X

Vroom Vroom https://t.co/F3n2Q3SLAl

Dec 24, 2022 · 1 like · 9,106 followers View post →

All mentions

Nicole Laurent, LMHC
@KetoCounselor · X

Vroom Vroom https://t.co/F3n2Q3SLAl

Dec 24, 2022 · 1 like · 9,106 followers View post →