Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content.

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Jonathan Laxton MD, FRCPC

@dr_jon_l · X

No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores, the actual amount of melatonin varied from -83% to +478% of what was stated on the bottle: https://t.co/Us95R43msA https://t.co/JL1uMPYeKH

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Maede

@Maede2024 · X

محتوای ملاتونین در بیش از ۷۱٪ از مکمل‌ها با ادعای روی برچسب مطابق نیست. ۲۶٪ از مکمل ها حاوی سروتونین هستند. پ.ن. مکمل های مورد بررسی در این مطالعه از فروشگاه‌های مواد غذایی و داروخانه‌های محلی در کانادا (انتاریو) خریداری شده اند. https://t.co/E4QGJnKDBD https://t.co/b4Wrt3v1Nl

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George Dawson

@dawso007 · X

Recent posts about melatonin: Open access article about significant product variability in terms of melatonin content and contaminants. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin C… https://t.co/mqYycxQ9Dv

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John Damianos, M.D.

@john_damianosMD · X

@SultanMahmoodMD @KewinSiah @drkeithsiau @RomeGastroPsych @TuesdayNightIBS @DrCalvinKoh @IBS_Maastricht @JohannahRuddy @AndrewOngML Cheap, yes, safe, theoretically... I'm always concerned about quality control, since melatonin concentration varies −83% to +478% of what's listed. I always recommend going for a reputable distributor! https://t.co/0G9Bbgq0oe https://t.co/TQu0Iuw7Ls

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Christina Pierpaoli Parker, PhD, DBSM

@ageambassador · X

@dianermacedo @Sleep_Strong @drcolleencarney @michaelgrandner @Dr_CLJackson @jadewuphd @ErichsenDaniel @SportSleepDoc @thesleepdoctor @ndwignall @theSBSM another common misconception/error = using melatonin as a sleep aid vs. phase-shifting tool. Most also probably don't recognize how variable doses run within and across supplements b/c of lack of regulation: https://t.co/O1JfIZezsE

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Ben Greenfield

@bengreenfield · X

Melatonin content varies widely in most supplements. Proceed with caution! Click here for the latest on this

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FD

@franke_dave · X

@BrandonLuuMD It’s probably inaccurate. Independent study of 31 brands - Actual melatonin content ranged from -83% to +478% compared to the labeled amount. https://t.co/5uFdErGsEw

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Maede

@Maede2024 · X

عصاره‌های گیاهی که معمولاً به این کپسول‌ها افزوده شده بودند شامل ریشه والریان، گل ساعتی، بابونه، اسکال‌کپ و هپس بودند. https://t.co/E4QGJnKDBD

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mhmazidi

@mhmazidi · X

RT @Maede2024: محتوای ملاتونین در بیش از ۷۱٪ از مکمل‌ها با ادعای روی برچسب مطابق نیست. ۲۶٪ از مکمل ها حاوی سروتونین هستند. پ.ن. مکمل های…

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Maede

@Maede2024 · X

محتوای ملاتونین در بیش از ۷۱٪ از مکمل‌ها با ادعای روی برچسب مطابق نیست. ۲۶٪ از مکمل ها حاوی سروتونین هستند. پ.ن. مکمل های مورد بررسی در این مطالعه از فروشگاه‌های مواد غذایی و داروخانه‌های محلی در کانادا (انتاریو) خریداری شده اند. https://t.co/E4QGJnKDBD https://t.co/b4Wrt3v1Nl

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Il potere forte è sempre più nelle mani di pochi

@iniziamoda0 · X

Prodotti e integratori naturali per la salute della melatonina: presenza di serotonina e variabilità significativa del contenuto di melatonina https://t.co/cv7lwWLBmT

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Inev May

@InevMay · X

@levelsio https://t.co/mBm9M7mSmL "Melatonin content was found to range from −83% to +478% of the labelled content. Additionally, lot-to-lot variable within a particular product varied by as much as 465%."

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The Crane Report 

@TheCraneReport · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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Doctor_David

@Doctor_David · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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(((Liz Ditz))). Mask up, y'all. Viruses are real.

@lizditz · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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Frank Han MD

@han_francis · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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Jonathan Laxton MD, FRCPC

@dr_jon_l · X

@GeorgeHuxl @rencar130 @doritmi @gorskon Do you not believe that your supplements should contain the amounts indicated on the bottle? That's pretty basic regulation. https://t.co/Us95R43msA

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Greedwashing StuffyCat

@greedwashing · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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Ellen

@Elle_Ham06 · X

RT @dr_jon_l: No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores…

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Jonathan Laxton MD, FRCPC

@dr_jon_l · X

No one is banning them - they are trying to improve regulation. This study showed that of 30 melatonin brands sold in stores, the actual amount of melatonin varied from -83% to +478% of what was stated on the bottle: https://t.co/Us95R43msA https://t.co/JL1uMPYeKH

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ソーラ@me/cfs

@OMwvw · X

参考② Erland LA, Saxena PK. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content. J Clin Sleep Med. 2017 Feb 15;13(2):275-281. doi: 10.5664/jcsm.6462. PMID: 27855744; PMCID: PMC5263083.

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echo

@somedayspeacee · X

@BeyzBetelgeuse Bu da içinde Melatonin'den başka şeyler bulunabileceği anlamına geliyor, ki bulunuyor; https://t.co/4iY3RZeVV4 conclusion kısmında açıklanmış, etiket ile pazarlanışında söylenilen şeyler uyuşmuyor, ekstra malzemeler var ve bu bilgimiz dışında vücudu etkiliyor. +

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Eve Beavers Fain is espacetimeCO

@espacetimeCO · X

@DorissLoh https://t.co/tzOlNIXQe2

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sagar

@schopsss · X

@RMB @robgo True. A study showed variance -83% to +478% than the concentration labeled. also found variability within a particular product varied by as much as ~460%. While it’s a hormone, it’s classified as a “supplement” so it’s less scrutinized https://t.co/hAExk326pc

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Brendan Chan

@chanpapas · X

RT @JCedernaes: A 2017 analysis of Canadian product found similar deviations in 31 supplements: #Melatonin content ranged -83% to +478% of…

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Jonathan Cedernaes

@JCedernaes · X

A 2017 analysis of Canadian product found similar deviations in 31 supplements: #Melatonin content ranged -83% to +478% of the labelled (mg) content. And lots of (!) lot-to-lot variability within a product: 465% And (!): Also often had herbal extracts https://t.co/olMtjmxyu6 https://t.co/U5p1B8Odoy

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I am

@atreasure_trove · X

@vwdouchebag Supplements aren't regulated in Canada, you're likely taking to much unexpectedly. "content was found to range from −83% to +478% of the labelled content" https://t.co/R3Nz5DtiGO

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George Dawson

@dawso007 · X

@evolutionarypsy @Duderichy Don't forget melatonin: https://t.co/cHEJVHZslE

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Miguel Angel Grullon C.

@miguel78910 · X

Productos y suplementos naturales para la salud de melatonina: presencia de serotonina y variabilidad significativa del contenido de melatonina. https://t.co/GJMdw6pYBE

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Medical Xpress

@physorg_health · X

Sleep experts advise parents to seek medical advice before giving #melatonin to #children @aasmorg https://t.co/Q0BQP9P5FE https://t.co/2fFmWMfliX

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Michael Sikorski

@mckorki · X

@SatchinPanda A classic example: 31 over-the-counter melatonin products had between -83% to +478% of labeled melatonin content. A pinch of Serotonin was found in 8. https://t.co/g8ndc9ZCg0

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Hans Collin

@HansCollin2 · X

@whotookPaigette @MrsWaldbrook @mildanalyst It could hurt! A lot! Melatonin can cause toxicity, like any other drug. https://t.co/MDQxiG5otJ One of the reasons is that the actual content of melatonin in OTC products varies between less than 83% to more than 478% (!) of what's declared on the label. https://t.co/erMZIofB7R

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Hans Collin

@HansCollin2 · X

En 2021 la melatonina fue el producto medicinal más consumido por niños, a pesar de que puede ser MUY tóxico. https://t.co/MDQxiFNN59 El contenido real de melatonina de esos productos varía de <83% a >478% (!) con respecto de lo que señala la etiqueta. https://t.co/erMZInXZJh

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Naftali Kaminski

@KaminskiMed · X

RT @DrCanapari: (Source: https://t.co/sJ8L06Gdyi ) (15/20)

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CC

@doccan18 · X

(Source: https://t.co/sJ8L06Gdyi ) (15/20)

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Joan Dalgleish

@JoanDalgleish · X

Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content https://t.co/8XSuNNcW68

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Ash Paul

@pash22 · X

RT @dawso007: Recent posts about melatonin: Open access article about significant product variability in terms of melatonin content and co…

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George Dawson

@dawso007 · X

Recent posts about melatonin: Open access article about significant product variability in terms of melatonin content and contaminants. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin C… https://t.co/mqYycxQ9Dv

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Tope Time

@DTope · X

RT @bengreenfield: Melatonin content varies widely in most supplements. Proceed with caution! Click here for the latest on this

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Dr Vaseem

@DrVaseemredux · X

RT @bengreenfield: Melatonin content varies widely in most supplements. Proceed with caution! Click here for the latest on this

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Ben Greenfield

@bengreenfield · X

Melatonin content varies widely in most supplements. Proceed with caution! Click here for the latest on this

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Jake Adler

@jakeradler · X

@MadhavMalhotra_ Here are a few

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Laura E Flores, MD, PhD

@LauraFlowersE · X

RT @DrDanielGih:

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sam

@sammy_ide · X

https://t.co/wUyDR8VAxy

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mel

@mlemth · X

i don't wanna just link a webMD article, but also probably no one will read through a whole ass journal of medicine (hint, ctrl+f 'melatonin') i don't mean these posts as like a warning against using melatonin, but there seems to be a lot of misuse. https://t.co/k8ji5JqNFa

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dr weimarstaja 2.0

@0_weimar2 · X

@ergasster @BowTiedOx 2/2 …but here is a link stating most products do not contain the labeled amount (-83% to +478%) and 26% contain serotonin, which should not be supplemented. https://t.co/QvOVFbbAyk

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Dr Celestino Gutiérrez González MD

@CelestinoGutirr · X

RT @john_damianosMD: @SultanMahmoodMD @KewinSiah @drkeithsiau @RomeGastroPsych @TuesdayNightIBS @DrCalvinKoh @IBS_Maastricht @JohannahRuddy…

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John Damianos, M.D.

@john_damianosMD · X

@SultanMahmoodMD @KewinSiah @drkeithsiau @RomeGastroPsych @TuesdayNightIBS @DrCalvinKoh @IBS_Maastricht @JohannahRuddy @AndrewOngML Cheap, yes, safe, theoretically... I'm always concerned about quality control, since melatonin concentration varies −83% to +478% of what's listed. I always recommend going for a reputable distributor! https://t.co/0G9Bbgq0oe https://t.co/TQu0Iuw7Ls

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L_ N___

@sqL_handLe · X

Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content 2017 February 15 https://t.co/v3fLZGEDT2

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はぎ

@hagi220 · X

「メラトニン含有量は、71％以上のサプリメントでラベル表示の10％のマージン内でラベルを満たしておらず、さらに26％がセロトニンを含んでいる」Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin C… https://t.co/DGklocQEdf

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Christina Pierpaoli Parker, PhD, DBSM

@ageambassador · X

@dianermacedo @Sleep_Strong @drcolleencarney @michaelgrandner @Dr_CLJackson @jadewuphd @ErichsenDaniel @SportSleepDoc @thesleepdoctor @ndwignall @theSBSM another common misconception/error = using melatonin as a sleep aid vs. phase-shifting tool. Most also probably don't recognize how variable doses run within and across supplements b/c of lack of regulation: https://t.co/O1JfIZezsE

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xmojigangax

@xMojigangax · X

@Artur95tov @ZecNutrition 3/3 Regierungsorganen auf der ganzen Welt, wie z.B. der FDA, reguliert wird. Wissenschaftliche Auswertungen von OTC-Marken haben ergeben, dass die Bandbreite von 83% weniger als auf dem Etikett angegeben bis zu 478% mehr als angegeben reicht! https://t.co/g6CO5bRisi #melatonin

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wukousen

@wukousen · X

RT @JCSMJournal: The #3 most read article in #JCSM in 2017 was #Melatonin Natural Health Products and Supplements: Presence of Serotonin an…