6. How quickly will spermatogenesis return after going off of testosterone? Very patient dependent with ranges reported between 110 days to 2 years. In one study 30% of men studied failed to achieve a sperm count > 5million/ml at the 1 year mark. https://t.co/SlSRuYZw9r
Age and duration of testosterone therapy predict time to return of sperm count after human chorionic gonadotropin therapy.
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Nov 2021 – Jul 2025Where it's discussed
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AI synopsis
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The discussions highlight the variability in spermatogenesis recovery times, with statements like the return being 'patient dependent' and a study noting '30% of men failed to achieve a sperm count > 5 million/ml at one year,' indicating a moderate level of engagement with the topic. The tone is informative, emphasizing individual differences and the complexity of recovery, rather than broad consensus or controversy.
The discussion reflects general acknowledgment of the study's findings, with some noting variability in recovery times.
Comments indicate moderate curiosity about the topic, especially regarding recovery timelines.
Participants are engaging by sharing specific details and open questions, but not deeply analyzing the study's methodology.
The discussion touches on practical considerations for patients and doctors, but does not highlight broad societal effects.
Abstract in brief
- The study found that older age and longer duration of testosterone (T) use delay the return of sperm count after treatment with high-dose hCG and SERM, with age being a more consistent factor.
- About 70% of the men achieved a sperm motile count over 5 million within 12 months, but only 64.8% of azoospermic men and 91.7% of cryptozoospermic men reached this goal, yet this did not necessarily predict treatment success.
- The findings suggest that physicians should be cautious about long-term testosterone therapy in men wanting to preserve fertility, and these results help inform counseling on the likelihood of sperm recovery after therapy.]
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6. How quickly will spermatogenesis return after going off of testosterone? Very patient dependent with ranges reported between 110 days to 2 years. In one study 30% of men studied failed to achieve a sperm count > 5million/ml at the 1 year mark. https://t.co/SlSRuYZw9r
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