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Eur J Nutr November 2016 PMID 27900447

Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes.

Tauseef A Khan, John L Sievenpiper

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Mentions

43
Peak: 4 in Feb 2021
across 4 sources since Jan 2019

Extended reach

643,190
potential audience

Total likes

6,105

Video views

435,746

Mentions per month

Jan 2019 – Jul 2025

Where it's discussed

  • Facebook16 posts
  • X / Twitter15 posts
  • News8 articles
  • YouTube4 videos

AI synopsis

What people are saying

The overall tone reflects a strong interest in scientific evidence, as seen in posts citing systematic reviews and high-quality studies, such as Sievenpiper's work, which argue that fructose isn't more harmful than other sugars when calorie intake is matched. The words and tone highlight a critical, evidence-based approach that encourages re-evaluating common assumptions about sugars and health, fostering deep engagement among participants.

AgreementModerate agreement

Most discussions support the article's main conclusion that sugars, including fructose, are not uniquely harmful when caloric intake is controlled, showing alignment with the publication's findings.

InterestHigh interest

The discussions demonstrate high interest, with many posters referencing detailed studies and engaging in nuanced debates about sugar's health effects.

EngagementHigh engagement

Posts include references to specific research and methodological critiques, indicating deep engagement with the topic.

ImpactModerate impact

The discussions could influence opinions about dietary sugar, especially by challenging common perceptions, though they may have limited immediate influence beyond academic and health-conscious communities.

Abstract in brief

  • Systematic reviews and high-quality studies have not proven that fructose-containing sugars are more harmful than other digestible carbohydrates when it comes to obesity, heart disease, or diabetes; their effects are primarily linked to the excess calories they provide.
  • Observational studies suggest a connection between sugary drinks and health risks like obesity and diabetes, but this is likely because these drinks are part of an overall unhealthy lifestyle, not solely because of the sugar content.
  • Focusing solely on sugar content isn't enough for a healthy diet; it's important to consider the entire dietary pattern and lifestyle, including nutrient quality and calorie balance, rather than just restricting specific sugars.
Read the full abstract

Top posts

Most liked on X and Bluesky
Mauricio Gonzalez MD.
@DrMauricioGon · X

Sugary drinks and chronic disease Khan TA, Sievenpiper JL. Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes. Eur J Nutr. 2016 Nov;55(Suppl 2):25-43

Feb 22, 2021 · 11 likes · 3 shares · 149,382 followers View post →
Danny Lennon
@NutritionDanny · X

Now consider this MA of isocaloric substitution trials: https://t.co/yxft6jPPI0 Fructose was exchanged for other CHO under energy-matched conditions. We can see that fructose has no uniquely harmful effect, when it’s substituted in place of other sugars and carbohydrates

Apr 3, 2023 · 7 likes · 8,898 followers View post →
Oscar Medina C.
@omedinacruz · X

@arodriguezllach Le añado info al debate: 1.El azúcar añadido a las bebibas es más perjudicial que en comidas https://t.co/dTwVa9A8Ex 2. Se puede mejorar el diseño del impuesto https://t.co/OyL10STsjS 3. Casi toda la región tiene algún tipo de impuesto, menos Colombia https://t.co/TU1HR0QrVa https://t.co/fcZfCM2mH2

Sep 2, 2021 · 7 likes · 1 share · 2,848 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@ascentovalhalla @CakeNutrition @edgefitnessper1 @Caveman_1975 @CanenePhd @ahhite @rustnutrition @Wendi_Irlbeck @StephHfitness @RDValerie @BioLayne @DNSatUofI Fructose on it own is only supported by ecological studies, animal models of overfeeding and select human intervention studies with supraphysiological doses or lack of control for energy. Read this (science vs uncontrolled "DocSci" (sim to BroSci

Sep 10, 2020 · 4 likes · 1 share · 10,517 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@ACShilton @6thsensemoment In that case I will tell you that there is no evidence fructose is any worse than other sugars when ingested in excess (or in moderation). UofT prof Sievenpiper has done a dozen studies on this. All sugar is equally as bad - major data here: https://t.co/K5rcRnFd7S

Apr 26, 2022 · 1 like · 10,517 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@MyNutritionSci @MattMadore576 @Alecsplaining @NutritionMadeS3 @krosenque @ScepticalDoctor @drmatthewnagra @fumimamu @JohnG_UK @TheVeganRD @JackNorrisRD @deirdre_tobias Similar to the fructose story: robust evidence from SR & MA of controlled trials doesnt show a "unique" fructose risk (obesity/T2DM) ie fructose-containing sugars don't behave any diff from other forms of carbohydrtaes {when in surplus} https://t.co/K5rcRnnBJi

Jun 7, 2021 · 1 like · 10,517 followers View post →

All mentions

The Truth About Sugar and Weight Management

This video explores the relationship between dietary sugar intake and body weight. It highlights findings from systematic reviews indicating that reducing sugar consumption can lead to weight loss in adults, while…

Metoda 3F · Jul 12, 2025 1,271 views
Danny Lennon
@NutritionDanny · X

Now consider this MA of isocaloric substitution trials: https://t.co/yxft6jPPI0 Fructose was exchanged for other CHO under energy-matched conditions. We can see that fructose has no uniquely harmful effect, when it’s substituted in place of other sugars and carbohydrates

Apr 3, 2023 · 7 likes · 8,898 followers View post →
たから＠腸活薬剤師｜日本腸活協会 代表理事
@takara_root · X

砂糖に関する論争: 肥満、心血管代謝疾患、糖尿病に関するシステマティック レビューControversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease a… https://t.co/B91E37RTrZ

Aug 18, 2022 · 1 like · 2,018 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@ACShilton @6thsensemoment In that case I will tell you that there is no evidence fructose is any worse than other sugars when ingested in excess (or in moderation). UofT prof Sievenpiper has done a dozen studies on this. All sugar is equally as bad - major data here: https://t.co/K5rcRnFd7S

Apr 26, 2022 · 1 like · 10,517 followers View post →
Alejandro Rodriguez Llach
@arodriguezllach · X

RT @omedinacruz: @arodriguezllach Le añado info al debate: 1.El azúcar añadido a las bebibas es más perjudicial que en comidas https://t.c…

Sep 2, 2021 · 1 share · 2,081 followers View post →
Oscar Medina C.
@omedinacruz · X

@arodriguezllach Le añado info al debate: 1.El azúcar añadido a las bebibas es más perjudicial que en comidas https://t.co/dTwVa9A8Ex 2. Se puede mejorar el diseño del impuesto https://t.co/OyL10STsjS 3. Casi toda la región tiene algún tipo de impuesto, menos Colombia https://t.co/TU1HR0QrVa https://t.co/fcZfCM2mH2

Sep 2, 2021 · 7 likes · 1 share · 2,848 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@MyNutritionSci @MattMadore576 @Alecsplaining @NutritionMadeS3 @krosenque @ScepticalDoctor @drmatthewnagra @fumimamu @JohnG_UK @TheVeganRD @JackNorrisRD @deirdre_tobias Similar to the fructose story: robust evidence from SR & MA of controlled trials doesnt show a "unique" fructose risk (obesity/T2DM) ie fructose-containing sugars don't behave any diff from other forms of carbohydrtaes {when in surplus} https://t.co/K5rcRnnBJi

Jun 7, 2021 · 1 like · 10,517 followers View post →
Daniel Courtney
@iambatdan · X

@MrFibbers I tried to find something specifically on sugar. This says sugar isn't really different from any other carbohydrate, but that on an individual level removing sugary drinks from your diet is good strategy: https://t.co/XGMlhNs1gI

May 30, 2021 · 152 followers View post →
José Alonso Sagundo Rodríguez
@JoseSagundo · X

RT @DrMauricioGon: Sugary drinks and chronic disease Khan TA, Sievenpiper JL. Controversies about sugars: results from systematic reviews…

Feb 23, 2021 · 3 shares · 132 followers View post →
Liliana
@Liliana58480629 · X

RT @DrMauricioGon: Sugary drinks and chronic disease Khan TA, Sievenpiper JL. Controversies about sugars: results from systematic reviews…

Feb 22, 2021 · 3 shares · 78 followers View post →
Raquel García✨
@_raqgarcia_ · X

RT @DrMauricioGon: Sugary drinks and chronic disease Khan TA, Sievenpiper JL. Controversies about sugars: results from systematic reviews…

Feb 22, 2021 · 3 shares · 1,812 followers View post →
Mauricio Gonzalez MD.
@DrMauricioGon · X

Sugary drinks and chronic disease Khan TA, Sievenpiper JL. Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes. Eur J Nutr. 2016 Nov;55(Suppl 2):25-43

Feb 22, 2021 · 11 likes · 3 shares · 149,382 followers View post →
Chef Ty, RDN, CNSC
@FoodFirst_Ty · X

@Bjorn_the_Beefy @BioPhysChemMark @rdbsmiles @DaveKeto @DoctorTro @BioLayne https://t.co/wPucklQN8B https://t.co/H9UXBRyOlJ https://t.co/qg6ZeD5iLZ https://t.co/3Z7QBgxCeb https://t.co/MOgl2emqFU https://t.co/Xj4R5fPqrz

Sep 20, 2020 · 1 like · 1 share · 2,137 followers View post →
con H de heterótrofo
@NutriRebel · X

RT @NanciGuestRDPhD: @ascentovalhalla @CakeNutrition @edgefitnessper1 @Caveman_1975 @CanenePhd @ahhite @rustnutrition @Wendi_Irlbeck @Steph…

Sep 10, 2020 · 1 share · 5,952 followers View post →
Nanci Guest PhD, RD, CSCS
@NanciGuestRDPhD · X

@ascentovalhalla @CakeNutrition @edgefitnessper1 @Caveman_1975 @CanenePhd @ahhite @rustnutrition @Wendi_Irlbeck @StephHfitness @RDValerie @BioLayne @DNSatUofI Fructose on it own is only supported by ecological studies, animal models of overfeeding and select human intervention studies with supraphysiological doses or lack of control for energy. Read this (science vs uncontrolled "DocSci" (sim to BroSci

Sep 10, 2020 · 4 likes · 1 share · 10,517 followers View post →
Darren Delaney, MSc ASCC
@DarDelFitness · X

Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes https://t.co/mc1IFoHWKp

Jan 27, 2019 · 371 followers View post →