Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increasingly difficult to justify... growing body of evidence of impressive results https://t.co/39vFZYI8n6 https://t.co/EA7H1xBFXv
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.
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Jan 2019 – Oct 2025Where it's discussed
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News449 articles
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What people are saying
The discussions reveal a strong consensus on the effectiveness and significance of the research, exemplified by mentions of the 2016 clinical trial, references to Johns Hopkins studies, and quotes highlighting the transformative effects on patients' mental health. The tone combines scientific appreciation with hope for broader clinical use, reflecting high engagement and perceived impact.
Most discussions strongly support the findings, emphasizing the positive and lasting effects of psilocybin on depression and anxiety in cancer patients.
Participants demonstrate high curiosity, referencing multiple studies, citing original papers, and discussing the implications for mental health treatment.
Many comments delve into scientific details, mention ongoing research, and debate the methods and significance, indicating deep involvement.
There's widespread recognition of the potential for psilocybin to revolutionize mental health care, with references to clinical trials, media coverage, and future applications.
Abstract in brief
- The study found that high doses of psilocybin significantly reduced depression and anxiety in patients with life-threatening cancer, and these positive effects lasted for up to six months.
- Participants experienced increased feelings of well-being, meaning in life, and optimism, along with decreased fear of death, with many attributing these improvements to their psilocybin experience.
- The results suggest that psilocybin could be a promising treatment for mental health issues related to serious illness, especially since the improvements were large, sustained, and linked to mystical-type experiences during the session.]
Top posts
Most liked on X and Bluesky@KissMyCarol Tried and true medicine.
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. https://t.co/M3Ijd62RUu
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - PubMed https://t.co/KWSbSbi7tb
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/izN5LTtRnJ
@SashaSisko Here's one that was buried in the supplemental materials for "Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial." https://t.co/KNO4eYgWJo https://t.co/kvSWPH6t59
All mentions
Synthetic Biology and Genetic Engineering of Psilocybin Producing E. coli
This video explores the biosynthesis and genetic modification of Escherichia coli to produce psilocybin, the psychoactive compound from magic mushrooms, and discusses the ethical implications of microbial genetic…
Psychedelics in Treating Mental Illness: Research Insights
This video delves into psychedelic-assisted therapy, focusing on ayahuasca, psilocybin, and LSD for depression and anxiety. It explores the neuroscience behind these substances, their psychological effects, and a review…
Therapeutic Potential of Psychedelic Mushrooms for Mental Health Treatment
Psychedelic mushrooms are showing promising results for mental health conditions, including depression, anxiety, and terminal illnesses. Studies demonstrate significant, lasting improvements, with increased well-being…
Psilocybin Effectively Reduces Depression and Anxiety in Cancer Patients
The study found that high doses of psilocybin significantly reduced depression and anxiety in patients with life-threatening cancer, with effects lasting up to six months. Participants experienced increased well-being…
Therapeutic Benefits of Psilocybin in Mental Health Treatment
Explore the potential therapeutic effects of psilocybin, highlighting its ability to reduce depression and anxiety in patients. This video discusses key studies showcasing the efficacy of psilocybin combined with…
Psychedelics in Psychiatry: Hope or Hype?
Psilocybin's Impact on Anxiety and Depression Treatment Advances
Psilocybin, the active component in magic mushrooms, is at the forefront of mental health research. This video explores how it affects brain chemistry, its potential to reduce anxiety and depression, and recent clinical…
@Jo_marchbhaer @20july1986 1. https://t.co/0bCwA2MiuI 2. https://t.co/dHFAE0AJx3 3. https://t.co/dHFAE0AJx3 4. https://t.co/lxQNwZi160 5. https://t.co/REwISsjPg0 6. https://t.co/1oz2Cn5Lav 7. https://t.co/OJBY9EU0Rg 8. https://t.co/XFbKgoAkZm 9. https://t.co/JEvoNuImcq 10. https://t.co/SoLgURQbc1
そんなとき、彼はある研究と出会います。 ジョンズ・ホプキンス大学が行った、がん患者とシロシビンに関する臨床試験。 その内容は「うつや不安の改善が認められた」というものでした。 https://t.co/aF2Vvb9Zvx
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/9UAFyeiFUI
یک کار آزمایی روی بیماران مبتلا به سرطان: دوز بسیار پایین (شبهدارونما) با دوز بالا (۲۵ میلیگرم) سیلوسایبین مقایسه شد. در شرایط حمایتی روانی، دوز بالا کاهش قابل توجه و سریعی در اضطراب (۸۳٪ پاسخ بالینی تا ۶ ماه) و بهبود کیفیت زندگی و پذیرش مرگ ایجاد کرد. https://t.co/ST0bJVbj1x
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - PMC https://t.co/6HkvdL0HEf
@vincristine @metcalph https://t.co/pDfyUYEYHQ Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial
https://t.co/x5YLL7IACI https://t.co/qtsYSCOzo3 https://t.co/1Vll7tS7tG https://t.co/UJkWqM9dn8 https://t.co/pirOczhzSb https://t.co/fjPzr4nyVQ https://t.co/ld1uHTr2IY https://t.co/bJ0ZTekJ55
@chloe21e8 Aren't psychedelics the chemical manifestation of the universe experiencing itself. Plus they induce neuroplasticity. https://t.co/Qv9fqC32JH https://t.co/hzLA1i2iOv https://t.co/PHS6JZFVx9 https://t.co/SKCrlHu52V https://t.co/pLs47IXSq6
@RLJ2DAY https://t.co/3dS0t4bBFW
@boxingscene @pugboxing Hope someone who with Martirosyan will read this. Double blind placebo study with psilocybin and life-threatening cancer. Study showed dramatic change in depression/anxiety, all around change of out look on life/death (significant changes for the better) https://t.co/3dS0t4bBFW
https://t.co/3dS0t4bBFW https://t.co/JJBTPyFpOX
@ColemanRidge Apparently the positive effect on mood/distress reduction is heavily mediated by whether a participant has a mystical experience. See e.g. https://t.co/0Cq7mbrYjk https://t.co/23av7PMFQ0
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - PMC… Psilocybin is making its rounds on media..article from 2016 why delay #Cancer #mushrooms https://t.co/9vFFj9rFBS
シロシビンが慢性疼痛にどう効くのか気になってたけど、痛みに関する否定的な考えや死への不安の減少させるっぽい 直接痛みを軽減するのではなく考え方や意識を変えるのすごい。 https://t.co/1RWjWdiLoI https://t.co/XRI1hDaSiY
@Ma_WuKong @Xonah_Brelan En 2016 se publicó algo bastante poco ortodoxo con resultados muy prometedores (enlace adjunto). Si la alternativa es la eutanasia, yo antes probaría la opción de la psilocibina (hongos del género Psilocybes). https://t.co/3VkGVfP6l2
Here is some additional material for your review & study: “Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial" by Griffiths et al. (2016) “Psilocybin-assisted treatment for
RT @TA920mx:
4/6 com és el càncer terminal. Griffiths et al (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer. Journal of Psychopharmacology, 30: 1181–1197. I les darreres entrevistes https://t.co/ybE1c8WpnK
3/6 Val la pena tenir present aquest treball que va publicar l'any 2016 i l'ajut que poden oferir aquests fàrmacs per alleujar una de les agonies més cruels, com és l'angoixa i la depressió que es deriva d'enfrontar-se a la inevitabilitat de la mort, https://t.co/c98Uagyx4C
RT @plantparadise7: @KissMyCarol Tried and true medicine.
RT @plantparadise7: @KissMyCarol Tried and true medicine.
RT @plantparadise7: @KissMyCarol Tried and true medicine.
RT @plantparadise7: @KissMyCarol Tried and true medicine.
@KissMyCarol Tried and true medicine.
https://t.co/qJ224pbZD0
https://t.co/MOw6YiDVqQ
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening… https://t.co/BVBTyCxVV1
@Randy_avila @whitezuelans Griffiths, R. R., et al. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of Psychopharmacology, 30(12), 1181-1197. Sorry toca que actualices te dejo este
References: 31/31 https://t.co/vSSlImWVLX https://t.co/HUDM6LcFSn https://t.co/JNlOyzEPH9 https://t.co/znxLnxVtwM https://t.co/LUoRrSG1Lv https://t.co/bXQX9VWYXB
@JulesEvans11 https://t.co/1O3m92Fcs7
@Jessicam6946 I've seen sources state that Depression/PTSD symptoms in terminal stage 4 cancer treatments were reduced completely through psilocyben treatments. https://t.co/tdqnaSr4c1
@Chr_Schoeps Zu Psilocybin gibt es einige Daten, zwar kleine, aber randomisierte Studien. Ähnliches zu MDMA und PTSD. Unabhängig davon wie man zu dem Freizeitgebrauch steht, in dem Kontext sollte das unkomplizierter erforscht werden können. https://t.co/C95zII75sM
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - Roland R Griffiths, Matthew W Johnson, Michael A Carducci, Annie Umbricht, William A Richards, … https://t.co/UhX9rGlxsM
Cell Reports (2018) Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. (10/11)
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/clOJct0Lfk
In a study conducted by Roland Griffiths featured in the National Library of Medicine, Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.
@joanmahp hahahahhahahaha t'estim JM!!! pero no tot es blanc o negre!!! https://t.co/8EM4nPr0UK
Psilocybin kann die Angst vor dem Tod reduzieren. #psychologie #palliativ #onkologie https://t.co/746vQ8bc6T
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening #cancer #mipcc22 https://t.co/n8dBsZz8cU
@Hausverkur Það eru í alvörunni lygilegar rannsóknaniðurstöðurnar um hvað sílósýbín gerir fyrir fólk með þunglyndi. Dæmi: https://t.co/BOgiQXYhXI
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening ... https://t.co/b3w1sdiZzW
@DrCMBurritt @CLOSLER @JHPsychedelics @N_Gukasyan @drjanaway @michaelpollan I see evidence for some real risk of adverse effects - but "immense destruction"? No - that statement doesn't appear to be grounded in the available evidence... https://t.co/iIPFIMzmaR https://t.co/Mu61Clc2Aw https://t.co/ZcULnDCSzd https://t.co/T8xnOMGj9V https://t.co/1ef1pGCyNr
An earlier study- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/fTG5IpaGpt
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/UWdiRc0qcn
“Studies have shown that psilocybin produces substantial and sustained decreases in depression and anxiety among patients with life-threatening cancer,” 8/
placebo and ssri trt: https://t.co/4dq2sKnAYV psilocybin trt: https://t.co/6McBLPgWX3 and https://t.co/86MUM4sHn0 real life difference estimate: https://t.co/NXnWvrN8Su
This is from 2016 but important to know about: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer. https://t.co/8kZ0HaN6bi
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial #love #amazing @Athens4Cannabis #beautiful #lifestyle #motivation #business #work #hello #hi https://t.co/YuevbAaXxV
RT @crsnq: @wduyck Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening canc…
@wduyck Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial 988 keer geciteerd. https://t.co/TgodjTAY7e
@badrenergic @ACNPorg Just a few short years ago: https://t.co/yoad6Lsz7X
RT @dreamgbutterfly: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening ca…
RT @D__Nickles: @SashaSisko Here's one that was buried in the supplemental materials for "Psilocybin produces substantial and sustained dec…
@ColinOCarroll1 I’m missing the distinction between a low, intentionally ineffective dose and a placebo. 1mg used this way in Griffiths et al 2016 https://t.co/qiOGyr6CEs https://t.co/ZdFc2YQYN3
https://t.co/RGp6PCHcfr
RT @AliBliPCdoc: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer…
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/izN5LTtRnJ
(7) (DOC) Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial | Thomas Roberts - https://t.co/q5FAGVsKLJ https://t.co/UwpgTvKHBw
@SashaSisko Here's one that was buried in the supplemental materials for "Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial." https://t.co/KNO4eYgWJo https://t.co/kvSWPH6t59
@Wdenemy @DirkSchwenk https://t.co/7S4O8VCn0x This would be the strongest study in connection to internal validity and clinical utility I can see. It’s on 50 cancer patients. Sounds promising but would need to dig deeper into the methods. After 6 months, changes in cancer prognosis might be relevant.
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening… https://t.co/ycUsWsVzyK
RT @xactoknife1: @AndrewYang not just PTSD Psilocybin produces substantial and sustained decreases in depression and anxiety in patients w…
RT @theresaboyle: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cance…
@Marktheflow 専門家がセッションを行うんですが、概ねいい影響のようです。驚くべきは1回の治療で半年効果が続いていること。神秘体験の結果、人生の意味などをポジティブに捉えられるようになるとか。確かに20-30%で精神的不快、不安が出るようですが、重篤ではないみたいですね。 https://t.co/qikPPW7ail
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/8BkDZVHp04
#Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Link to original 2016 paper in article. https://t.co/31E9c9dOTv
RT @Ava_Mason_1: Hi all, I have decided to start a science channel! The first video looks at whether psychedelics could treat depression or…
Hi all, I have decided to start a science channel! The first video looks at whether psychedelics could treat depression or anxiety in the future. I talk about it from a neuroscience, psychology, and research perspective! https://t.co/M3eDpC4iBB
A good academic review of the physiological and psychological benefits of psychedelics-based medicine for depression/anxiety. Note that there is overlap/reinforcement of these benefits. #psychedelicstocks #LSD #ayahuasca #psilocybin #depression #anxiety https://t.co/v0NRxgpGEZ
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/Zmjy0iR3CQ
Psilocybin-assisted psychotherapy has also been shown to be effective in the treatment of depression and anxiety in cancer patients https://t.co/Q3SBnchjex
https://t.co/m9rxMaRCRX
@SkyNews @skrivebordskiwi So happy for them! And to those asking why this would be any good: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/nyyBmRD9ZI
@GidMK @CaulfieldTim @TheSciBabe @picardonhealth The paper you cite says the opposite of what you claim it does. https://t.co/hv0dost77d "At 6-month follow-up, these changes were sustained, with about 80% of participants continuing to show clinically significant decreases in depressed mood and anxiety."
Psilocybin produces substantial and sustained decreases in #depression and #anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/BYwaBBjz8C #mentalhealth #psilocybinresearch
@Gorman_JG @RichardJGrant They’re already doing this work MDMA-assisted psychotherapy for PTSD: https://t.co/4H5eJDxOaz Ketamine for depression: https://t.co/mg7G3Mm5aa Psilocybin for depression and anxiety: https://t.co/biiPy4Ajr0 Etc Johns Hopkins leads a lot of this kind of work
RT @md_frost: Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increas…
RT @pdiamandisii: Today on NeuroscIQ we are talking about the Therapeutic Potential of #Psychedelics for #neurology disorders including #de…
Today on NeuroscIQ we are talking about the Therapeutic Potential of #Psychedelics for #neurology disorders including #depression #cancer #addiction. Come check it out! #psychiatry #neuroscience #inflammation #neuropath https://t.co/b7BZZemgED
RT @md_frost: Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increas…
RT @theresaboyle: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cance…
RT @theresaboyle: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cance…
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - PubMed https://t.co/KWSbSbi7tb
RT @md_frost: Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increas…
RT @md_frost: Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increas…
RT @md_frost: Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increas…
Restricting the use of psychedelics at end of life (and possibly in other settings- depression, addiction, others) is increasingly difficult to justify... growing body of evidence of impressive results https://t.co/39vFZYI8n6 https://t.co/EA7H1xBFXv
“A single dose of psilocybin produced substantial and enduring decreases in depressed mood and anxiety along with increases in quality of life and decreases in death anxiety in patients with a life-threatening cancer diagnosis.” https://t.co/2JxKvZlwxf #mentalhealth #depresion
@Wickedscosplay @Eleine_Sun yknow both of you girls can be right? https://t.co/JneAUhyziF https://t.co/M1zHVp8Eun https://t.co/Xo6gqPNQ9g
@Myob_Myob @PyramidRealm You don’t get “medical papers” from a university study. But you do get the entire 2016 John Hopkins Trial to read. But we both know you’re too stubborn to read FACTS. https://t.co/bia9L1h4C0
@psych_wijchen Maar kijk alleen eens naar de onderzoeken die op het Johns Hopkins lopen over psilocybine en depressie. Hier heb je er een: https://t.co/uQIL6HDHWX
@iam_687 @geoffblades They've been shown in some controlled settings to give a non-trivial percentage of patients longterm relief from ruminating anxiety and/or depression. I wouldn't necessarily advise it because I can't guarantee safe replication. Bad trips can worsen it. https://t.co/bZoNralC6Z
RT @drrickbarnett: https://t.co/w2YZeD94aL @JohnsHopkins #psychedelicstudies
https://t.co/w2YZeD94aL @JohnsHopkins #psychedelicstudies
@Duncan76921685 @AlexWodak Psilocybin for depression: https://t.co/hmEfUvGyF0
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/sr3kNh6OvQ
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/WefvOtPI58
@AndrewYang not just PTSD Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-bli... - PubMed - NCBI https://t.co/VpL740bMjZ
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/WefvOtPI58
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/QkZNYdJtvZ
https://t.co/UUxjeX7wKp
RT @puddleg: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A…
RT @puddleg: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A…
RT @puddleg: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A…
RT @puddleg: Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A…
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. https://t.co/M3Ijd62RUu
https://t.co/f91Ff9vv5b https://t.co/f91Ff9vv5b
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial https://t.co/WefvOtPI58
@DavidLe60561687 https://t.co/qVnmZ0VqWi