December 2016 PMID 28025528

Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in Adult Patients at Nutritional Risk.

Silvia Cappello, Emanuele Cereda, Mariangela Rondanelli, Catherine Klersy, Barbara Cameletti, Riccardo Albertini, Daniela Magno, Marilisa Caraccia, Annalisa Turri, Riccardo Caccialanza

Mentions

13
Peak: 9 in Oct 2025
across 4 sources since Nov 2017

Extended reach

1,287
potential audience

Total likes

23

Video views

707

Mentions per month

Nov 2017 – Oct 2025

Where it's discussed

  • YouTube9 videos
  • Facebook2 posts
  • X / Twitter1 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions show a general recognition of the importance of vitamin levels, with posts mentioning clinicians should be cautious about supplementing vitamin B12 and noting its potential as a warning marker for mortality risk. The tone is cautious and reflective, indicating interest in the real-world application of the research findings, even as some broaden the discussion to related topics like cognitive decline and aging.

AgreementModerate agreement

Most discussions acknowledge the potential significance of high vitamin B12 levels as predictors of patient outcomes, suggesting some level of agreement on its clinical importance.

InterestModerate interest

The discussions demonstrate moderate interest, touching on broader topics like aging and cognitive decline, which are relevant but not directly focused on the study's specifics.

EngagementModerate engagement

Participants reference the publication and related research, indicating a moderate depth of engagement, especially in understanding implications for patient care.

ImpactModerate impact

Since the discussions highlight possible impacts on clinical practices and future research, they suggest a moderate perceived influence on health strategies.

Abstract in brief

  • Elevated plasma vitamin B12 concentrations (above 1000 pg/mL) are linked to higher inhospital mortality among adult patients at nutritional risk, regardless of factors like age, gender, body weight, or existing health conditions.
  • Patients with high vitamin B12 levels tend to stay longer in the hospital (median of 25 days vs. 23 days), and these elevated levels are also independently associated with longer hospital stays.
  • The study suggests that high vitamin B12 levels may be a warning marker for increased risk of death and longer hospital stays in this patient group, but the exact reasons for this association are still unclear, so doctors should be cautious about unnecessary vitamin B12 supplementation.]

Top posts

Most liked on X and Bluesky
cinnamonization
@cinnamonization · X

@krosenque @MyNutritionSci @ScepticalDoctor @JulietteNYRO @ExcelYourself "Although the underlying mechanisms are still unknown [...] , clinicians should be aware of the potential negative impact of high vitamin B12 concentrations in hospitalized patients at nutritional risk and avoid inappropriate vitamin supplementation" ➡️

Jun 6, 2021 · 582 followers View post →
Allen Tien, MD, MHS mdlogix.com 94,698 田一彦
@allentien.bsky.social · Bluesky

#Aging and #Dementia: Lower vitamin B6 status associated with 3.5 times higher risk of accelerated cognitive decline http://www.mdpi.com/2072-6643/9/1/53

Nov 6, 2017 View post →

All mentions

cinnamonization
@cinnamonization · X

@krosenque @MyNutritionSci @ScepticalDoctor @JulietteNYRO @ExcelYourself "Although the underlying mechanisms are still unknown [...] , clinicians should be aware of the potential negative impact of high vitamin B12 concentrations in hospitalized patients at nutritional risk and avoid inappropriate vitamin supplementation" ➡️

Jun 6, 2021 · 582 followers View post →
Allen Tien, MD, MHS mdlogix.com 94,698 田一彦
@allentien.bsky.social · Bluesky

#Aging and #Dementia: Lower vitamin B6 status associated with 3.5 times higher risk of accelerated cognitive decline http://www.mdpi.com/2072-6643/9/1/53

Nov 6, 2017 View post →